Collagen Treatment in Facial Nerve Palsy
Facial Nerve Palsy
About this trial
This is an interventional treatment trial for Facial Nerve Palsy focused on measuring Facial nerve palsy, Kabat method, Collagen injections, Electromyography
Eligibility Criteria
Inclusion Criteria:
- patients with a medical diagnosis of long-term unilateral peripheral axonotmesis of the facial nerve
Exclusion Criteria:
- patients with facial palsy caused by central nerve disease;
- patients with a history of recurrent facial palsy;
- patients with a facial skin disease hampering the possibility of injecting the drug; - patients with difficulty in moving their face due to previous plastic surgery or facial surgery;
- patients with systemic diseases that can affect facial electromyography;
- patients deemed inappropriate by the researchers.
- patients with a history of hypersensitivity to any collagen solution constituent or showing pregnancy, lactation, neuromuscular junction disorders (myastenia gravis), peripheral motor neuropathies, or active infections will be also excluded.
Sites / Locations
- UNITER ONLUS for balance and rehabilitation research
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
kabat
collagen injection
Rehabilitation will be started in both groups of patients and it will be carried out according to Kabat et al., i.e. a proprioceptive neuromuscular facilitation procedure, twice a week for 8 weeks, by an experienced physioptherapist
Injections of an equally-balanced solution of MD Neural, MD Matrix and MD Muscle (Guna S.p.a., Milan-Italy), containing collagen of porcine origin, will be administered subcutaneously after applying lidocaine/prilocaine cream on the affected side, by a skilled otonaryngologist in the field of injection treatments, twice a week for 8 weeks