Colonizing Neurogenic Bladders With Benign Flora
Spinal Cord Injury, Urinary Tract Infection
About this trial
This is an interventional prevention trial for Spinal Cord Injury focused on measuring biofilm, clinical trial, Escherichia coli, urinary catheter
Eligibility Criteria
Inclusion Criteria:
Patients followed at the MEDVAMC who have sustained spinal cord injury > 12 months earlier, suffer from neurogenic bladder, practice intermittent bladder catheterization, and who have had at least 1 symptomatic UTI in the past will be enrolled.
Exclusion Criteria:
Exclusion criteria will include obstructive urolithiasis, indwelling bladder or nephrostomy catheters, supravesical urinary diversion, vesicoureteral reflux, active malignancy, uncontrolled diabetes mellitus, AIDS, requirement for immunosuppressive medication, or current antibiotic therapy. Women of childbearing age must have a negative pregnancy test before enrolling in the study, and they must utilize effective birth control methods during the study and for 3 months after the study is concluded.
Sites / Locations
- Michael E DeBakey VA Medical Center
Arms of the Study
Arm 1
Other
Arm 1
insertion of E. coli coated catheter