Combination Chemotherapy With or Without Darbepoetin Alfa in Treating Women With Stage III Breast Cancer
Breast Cancer
About this trial
This is an interventional treatment trial for Breast Cancer focused on measuring stage IIIA breast cancer, stage IIIC breast cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: Histologically confirmed breast cancer Stage III disease (pT1, N2-3, M0) No metastatic disease by thoracic x-ray, full-body bone scan, and liver sonography No inflammatory disease or Paget's disease Disease completely resected (R0) and ≥ 10 axillary lymph nodes removed Underwent surgery approximately 42 days ago At least 9 positive lymph nodes No prior sequential mastectomy Hormone receptor status not specified PATIENT CHARACTERISTICS: Female Menopausal status not specified ECOG performance status 0-1 WBC ≥ 3,500/mm^3 Creatinine ≤ 1.4 mg/dL Platelet count ≥ 100,000/mm^3 Bilirubin ≤ 2.0 mg/dL No pre-existing symptomatic peripheral neuropathy Not pregnant or nursing No hypersensitivity to darbepoetin alfa, epoetin alfa, or any of their components No other malignancy except curatively treated basal cell skin cancer or carcinoma in situ of the cervix PRIOR CONCURRENT THERAPY: See Disease Characteristics No participation in another clinical study No prior therapies that would preclude study participation
Sites / Locations
- Kreiskrankenhaus AurichRecruiting
- Maria-Hilf-KrankenhausRecruiting
- Evangelisches Krankenhaus - Bergisch GladbachRecruiting
- Knappschaft KrankenhausRecruiting
- Praxis fuer Haematologie - OnkologieRecruiting
- Johanniter-Krankenhaus BonnRecruiting
- Onkologische GemeinschaftspraxisRecruiting
- St. Rochus HospitalRecruiting
- Praxis Fuer Haematologie Internistische OnkologieRecruiting
- Medizinische Universitaetsklinik I at the University of CologneRecruiting
- St. Elisabeth-Krankenhaus - KoelnRecruiting
- Klinikum DeggendorfRecruiting
- Universitaetsklinikum DuesseldorfRecruiting
- Onkologische SchwerpunktpraxisRecruiting
- Alfried Krupp KrankenhausRecruiting
- Universitaetsklinikum EssenRecruiting
- II Medizinische Klinik - Klinikum FuerthRecruiting
- Evangelische Kliniken Gelsenkirchen GmbHRecruiting
- Wilhelm-Anton-Hospital gGmbH, GochRecruiting
- Maria-Josef-Hospital Greven GmbHRecruiting
- Allgemeines Krankenhaus HagenRecruiting
- Evangelisches Krankenhaus Hagen-Haspe GmbHRecruiting
- Henriettenstiftung KrankenhausRecruiting
- Praxisgemeinschaft fuer Gynaekologische OnkologieRecruiting
- Universitaetsklinikum des SaarlandesRecruiting
- Klinikum Kaufbeuren OstallgaeuRecruiting
- Katholisches Klinikum Koblenz MarienhofRecruiting
- Frankenwald KlinikRecruiting
- Internistische Onkologische Praxis - KronachRecruiting
- St. Marien Hospital - LuenenRecruiting
- St. Vincenz und Elisabeth HospitalRecruiting
- Klinikum MemmingenRecruiting
- Klinikum MindenRecruiting
- Krankenhaus BethanienRecruiting
- Marienhaus Klinikum St. Elisabeth NeuwiedRecruiting
- Evangelisches Krankenhaus OberhausenRecruiting
- Internistische Gemeinschaftspraxis - OffenbachRecruiting
- Praxis fuer Haematologie und OnkoligieRecruiting
- Klinikum Suedstadt RostockRecruiting
- Marienkrankenhaus Schwerte gem. GmbHRecruiting
- Staedtisches Klinikum SolingenRecruiting
- Praxis Fuer Internistische Haematologie / OnkologieRecruiting
- Katherinen-Hospital gGmbHRecruiting
- Marien-Hospital Wesel gGmbHRecruiting
- Marien-Hospital WittenRecruiting
- Bethesda Krankenhaus Wuppertal gGmbHRecruiting
- Haematologie / Onkologische SchwerpunktpraxisRecruiting