search
Back to results

Community Intervention Trial for Youth (CITY) Study

Primary Purpose

HIV Infections

Status
Completed
Phase
Phase 2
Locations
United States
Study Type
Interventional
Intervention
Community-Level Intervention
Sponsored by
Centers for Disease Control and Prevention
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional prevention trial for HIV Infections focused on measuring Homosexuality, Male, Adolescents, Minority Groups, Community Participation, Community Surveys, HIV Seronegativity, HIV

Eligibility Criteria

15 Years - 25 Years (Child, Adult)MaleAccepts Healthy Volunteers

Inclusion Criteria: 15-25 years of age reports having sexual contact with another man in the past year meets the race/ethnicity eligibility criteria for the particular community Exclusion Criteria:

Sites / Locations

  • University of Alabama - Birmingham
  • Childrens Hospital Los Angeles
  • University of California-San Francisco, Center for AIDS Prevention Studies
  • Georgia State University
  • University of Illinois at Chicago
  • Education Development Center
  • University of Minnesota Youth and AIDS Projects
  • Medical College of Wisconsin, Center for AIDS Intervention Research

Outcomes

Primary Outcome Measures

1) unprotected anal intercourse with a male partner in the past 3 months
2) unprotected anal intercourse at last sex with a main male partner (among participants with a male sex partner in the past 3 months and in the past year)
3) unprotected anal intercourse at last sex with the most recent non-main male partner (among participants with a male sex partner in the past 3 months and in the past year)

Secondary Outcome Measures

Full Information

First Posted
September 9, 2005
Last Updated
September 26, 2012
Sponsor
Centers for Disease Control and Prevention
search

1. Study Identification

Unique Protocol Identification Number
NCT00164580
Brief Title
Community Intervention Trial for Youth (CITY) Study
Official Title
Prevention of HIV Infection in Youth at Risk: Developing Community-Level Intervention Strategies That Work (Community Intervention Trial for Youth (CITY) Study)
Study Type
Interventional

2. Study Status

Record Verification Date
September 2012
Overall Recruitment Status
Completed
Study Start Date
October 1996 (undefined)
Primary Completion Date
August 2002 (Actual)
Study Completion Date
August 2004 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Centers for Disease Control and Prevention

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
The purpose of this study is to test whether a multi-component, community-level, HIV-prevention intervention is more effective than existing HIV prevention activities in reducing unprotected anal intercourse (UAI) among men ages 15-25 who have sex with men.
Detailed Description
In recent years, there have been increases in the rates of unprotected anal intercourse (UAI) reported by men who have sex with men (MSM) and in the numbers of newly diagnosed HIV infections among MSM. Surveys of young MSM (ages 15-29) in numerous U.S. cities from 1994-2000 found an HIV prevalence of 2.2% to 18%, however, HIV prevalence was higher among young MSM of color than among white men. In a survey of 23-29 year-old MSM,nearly 1/3 of African-American men and 15% of Hispanic/Latino men were infected with HIV. The Community Intervention Trial for Youth (CITY) study is a 13-community randomized control trial designed to evaluate a multi-component, community-level intervention for MSM ages 15-25 (i.e., young MSM or YMSM). All 13 communities have some form of HIV-prevention activities naturally occurring in their jurisdiction, but 6 of the 13 communities were randomly assigned to also receive the multi-component intervention (1 additional city served as a case study and also received the intervention). This intervention includes 4 components: 1) community health advisor network (CHAN) consisting of YMSM who conduct outreach to their peers, including linking other YMSM to community services and conducting other parts of the intervention; 2) social marketing, to include the use media to disseminate HIV risk-reduction messages and promote positive norms for safer sex; 3) large group events with an HIV prevention theme; and 4) small group activities/workshops that focus on increasing HIV prevention skills and enhancing a positive self-identity. The study population varies by site based on the specific racial or ethnic groups of YMSM that are targeted. African-American YMSM are the study population in Atlanta, Georgia (comparison site); Birmingham, Alabama (intervention site); and Chicago, Illinois (intervention site). Hispanic/Latino YMSM are the study population in Washington Heights/South Bronx, New York (intervention site); Jackson Heights/Queens, New York (comparison site); Orange County, California (intervention site); and San Gabriel Valley, California (comparison site). Asian and Pacific Islander YMSM are the study population in Seattle, Washington (intervention site) and San Diego, California (comparison site). YMSM regardless or race/ethnicity are the study population in Milwaukee, Wisconsin (intervention site); Detroit, Michigan (comparison site), Minneapolis, Minnesota (comparison site); and West Hollywood, California (intervention site). The primary goals of the intervention are to 1) decrease UAI with any male partners; 2) decrease UAI with main male partners; and 3) decrease UAI with non-main (i.e., casual) male partners. Using a venue-based, time/space sampling strategy in each community, cross-sectional samples of YMSM were interviewed from May-August across 4 years (1999-2002). Data collected in 1999 and 2000 were prior to the implementation of the multi-component intervention, and data collected in 2001 and 2002 were during the implementation of the intervention.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
HIV Infections
Keywords
Homosexuality, Male, Adolescents, Minority Groups, Community Participation, Community Surveys, HIV Seronegativity, HIV

7. Study Design

Primary Purpose
Prevention
Study Phase
Phase 2, Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
12000 (false)

8. Arms, Groups, and Interventions

Intervention Type
Behavioral
Intervention Name(s)
Community-Level Intervention
Primary Outcome Measure Information:
Title
1) unprotected anal intercourse with a male partner in the past 3 months
Title
2) unprotected anal intercourse at last sex with a main male partner (among participants with a male sex partner in the past 3 months and in the past year)
Title
3) unprotected anal intercourse at last sex with the most recent non-main male partner (among participants with a male sex partner in the past 3 months and in the past year)

10. Eligibility

Sex
Male
Minimum Age & Unit of Time
15 Years
Maximum Age & Unit of Time
25 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: 15-25 years of age reports having sexual contact with another man in the past year meets the race/ethnicity eligibility criteria for the particular community Exclusion Criteria:
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Carolyn A Guenther-Grey, M.A.
Organizational Affiliation
Centers for Disease Control and Prevention
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Alabama - Birmingham
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35294
Country
United States
Facility Name
Childrens Hospital Los Angeles
City
Los Angeles
State/Province
California
ZIP/Postal Code
90027
Country
United States
Facility Name
University of California-San Francisco, Center for AIDS Prevention Studies
City
San Francisco
State/Province
California
ZIP/Postal Code
94105
Country
United States
Facility Name
Georgia State University
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30303
Country
United States
Facility Name
University of Illinois at Chicago
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60607
Country
United States
Facility Name
Education Development Center
City
Newton
State/Province
Massachusetts
ZIP/Postal Code
02158
Country
United States
Facility Name
University of Minnesota Youth and AIDS Projects
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
55403
Country
United States
Facility Name
Medical College of Wisconsin, Center for AIDS Intervention Research
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53202
Country
United States

12. IPD Sharing Statement

Citations:
PubMed Identifier
15187480
Citation
Agronick G, O'Donnell L, Stueve A, Doval AS, Duran R, Vargo S. Sexual behaviors and risks among bisexually- and gay-identified young Latino men. AIDS Behav. 2004 Jun;8(2):185-97. doi: 10.1023/B:AIBE.0000030249.11679.d0.
Results Reference
background
PubMed Identifier
9642428
Citation
Choi KH, Yep GA, Kumekawa E. HIV prevention among Asian and Pacific Islander American men who have sex with men: a critical review of theoretical models and directions for future research. AIDS Educ Prev. 1998 Jun;10(3 Suppl):19-30.
Results Reference
background
Citation
Choi KH, Kumekawa E, Dang Q, Kegeles SM, Hays RB, Stall R. Risk and protective factors affecting sexual behavior among young Asian and Pacific Islander men who have sex with men: Implications for HIV prevention. Journal of Sex Education and Therapy, 24(1&2): 47-55, 1999.
Results Reference
background
PubMed Identifier
12512848
Citation
Choi KH, Han CS, Hudes ES, Kegeles S. Unprotected sex and associated risk factors among young Asian and Pacific Islander men who have sex with men. AIDS Educ Prev. 2002 Dec;14(6):472-81. doi: 10.1521/aeap.14.8.472.24114.
Results Reference
background
PubMed Identifier
16080456
Citation
Guenther-Grey CA, Varnell S, Weiser JI, Mathy RM, O'Donnell L, Stueve A, Remafedi G; Community Intervention Trial for Youth Study Team. Trends in sexual risk-taking among urban young men who have sex with men, 1999-2002. J Natl Med Assoc. 2005 Jul;97(7 Suppl):38S-43S.
Results Reference
background
PubMed Identifier
15226130
Citation
Hart T, Peterson JL; Community Intervention Trial for Youth Study Team. Predictors of risky sexual behavior among young African American men who have sex with men. Am J Public Health. 2004 Jul;94(7):1122-4. doi: 10.2105/ajph.94.7.1122.
Results Reference
background
Citation
Mashburn AJ, Peterson JL, Bakeman R, Miller RL, Clark LF, and the Community Intervention Trial for Youth Study Team. Influences on HIV testing among young African-American men who have sex with men and the moderating effect of the geographic setting. Journal of Community Psychology 32(1): 45-60, 2004.
Results Reference
background
PubMed Identifier
14582599
Citation
Miller RL, Bedney BJ, Guenther-Grey C; CITY Project Study Team. Assessing organizational capacity to deliver HIV prevention services collaboratively: tales from the field. Health Educ Behav. 2003 Oct;30(5):582-600. doi: 10.1177/1090198103255327.
Results Reference
background
PubMed Identifier
11889287
Citation
Muhib FB, Lin LS, Stueve A, Miller RL, Ford WL, Johnson WD, Smith PJ; Community Intervention Trial for Youth Study Team. A venue-based method for sampling hard-to-reach populations. Public Health Rep. 2001;116 Suppl 1(Suppl 1):216-22. doi: 10.1093/phr/116.S1.216.
Results Reference
background
PubMed Identifier
12512847
Citation
O'Donnell L, Agronick G, San Doval A, Duran R, Myint-U A, Stueve A. Ethnic and gay community attachments and sexual risk behaviors among urban Latino young men who have sex with men. AIDS Educ Prev. 2002 Dec;14(6):457-71. doi: 10.1521/aeap.14.8.457.24109.
Results Reference
background
Citation
Peterson JL, Bakeman R, Stokes J, and the Community Intervention Trial for Youth Study Team. Racial/ethnic patterns of HIV sexual risk behaviors among young men who have sex with men. Journal of the Gay and Lesbian Medical Association 5(4): 155-162, 2001.
Results Reference
background
PubMed Identifier
12359375
Citation
Remafedi G. Suicidality in a venue-based sample of young men who have sex with men. J Adolesc Health. 2002 Oct;31(4):305-10. doi: 10.1016/s1054-139x(02)00405-6.
Results Reference
background
PubMed Identifier
10709789
Citation
Seal DW, Bloom FR, Somlai AM. Dilemmas in conducting qualitative sex research in applied field settings. Health Educ Behav. 2000 Feb;27(1):10-23. doi: 10.1177/109019810002700102.
Results Reference
background
PubMed Identifier
10716014
Citation
Seal DW, Kelly JA, Bloom FR, Stevenson LY, Coley BI, Broyles LA. HIV prevention with young men who have sex with men: what young men themselves say is needed. Medical College of Wisconsin CITY Project Research Team. AIDS Care. 2000 Feb;12(1):5-26. doi: 10.1080/09540120047431.
Results Reference
background
PubMed Identifier
11392935
Citation
Stueve A, O'Donnell LN, Duran R, San Doval A, Blome J. Time-space sampling in minority communities: results with young Latino men who have sex with men. Am J Public Health. 2001 Jun;91(6):922-6. doi: 10.2105/ajph.91.6.922.
Results Reference
background
PubMed Identifier
12512849
Citation
Stueve A, O'Donnell L, Duran R, San Doval A, Geier J; Community Intervention Trial for Youth Study Team. Being high and taking sexual risks: findings from a multisite survey of urban young men who have sex with men. AIDS Educ Prev. 2002 Dec;14(6):482-95. doi: 10.1521/aeap.14.8.482.24108.
Results Reference
background

Learn more about this trial

Community Intervention Trial for Youth (CITY) Study

We'll reach out to this number within 24 hrs