Comparison of Back-loaded vs Preloaded Fiducial Needles in EUS-guided Fiducial Marker Placement in Pancreatic Cancer.
Pancreatic Cancer
About this trial
This is an interventional treatment trial for Pancreatic Cancer focused on measuring Pancreatic cancer, Image guided radiation therapy, Fiducial marker placement, Endoscopic ultrasound
Eligibility Criteria
Inclusion Criteria:
• Patients with pathologically confirmed pancreatic cancer referred for image guided radiation therapy (IGRT)
Exclusion Criteria:
- Age <18
- Inability to consent
- Known coagulopathy/thrombocytopenia (INR >1.5, platelets <75)
- Patients on antiplatelet/anticoagulant medication that cannot safely be discontinued 5-7 days prior to the procedure
- Gold allergy
- Current infection
- EUS evidence of vessel interfering with path of fiducial marker
- Pregnancy
Sites / Locations
- University of Colorado Hospital
- Moffitt Cancer Center
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Back-loaded needle
Preloaded Needle
The patients will undergo Linear EUS and have fiducial marker placement via a traditional 22G back-loaded needle. CRFs will be used to record data for primary and secondary endpoints.
The patients will undergo Linear EUS and have fiducial marker placement via a traditional 22G preloaded needle. CRFs will be used to record data for primary and secondary endpoints.