Comparison of Barium Enema, Computed Tomographic Colonography, and Colonoscopy in Detecting Colon Cancer
Colorectal Cancer
About this trial
This is an interventional diagnostic trial for Colorectal Cancer focused on measuring colon cancer, rectal cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: One of the following must be present: At least 1 positive fecal occult blood test within the past 6 months Iron deficiency anemia, defined as: Hemoglobin less than 13 g/dL (males) Hemoglobin less than 12 g/dL (females) Ferritin less than 45 g/dL Episode of bright red blood per the rectum Family history of colon cancer or adenoma One first-degree relative diagnosed with colon cancer or adenoma at age 60 or under OR Two first-degree relatives diagnosed with colon cancer or adenoma at any age No active gastrointestinal hemorrhage, including any of the following: Reported or witnessed hematemesis Melenic stools Melenemesis Multiple episodes of hematochezia within the past 2 months PATIENT CHARACTERISTICS: Age: 18 and over Performance status: Not specified Life expectancy: Not specified Hematopoietic: See Disease Characteristics Hepatic: Not specified Renal: Not specified Cardiovascular: No myocardial infarction or cerebrovascular accident within the past 6 weeks Pulmonary: No respiratory failure within the past 6 weeks Other: No serious medical disorder (e.g., sepsis) within the past 6 weeks Weight less than 300 pounds Willing and able to undergo endoscopic or radiologic procedures No need for special precautions in performing endoscopic procedures (e.g., antibiotic prophylaxis or complicated anticoagulation reversal) No prisoners Not pregnant Negative pregnancy test Fertile patients must use effective contraception PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: Not specified Endocrine therapy: Not specified Radiotherapy: Not specified Surgery: Not specified Other: No other concurrent clinical trial participation involving drugs, medical devices, and/or biologics
Sites / Locations
- Rebecca and John Moores UCSD Cancer Center
- California Pacific Medical Center - Pacific Campus
- California Pacific Medical Center - California Campus
- Veterans Affairs Medical Center - San Francisco
- Indian River Radiology
- University of Chicago Cancer Research Center
- Troy Internal Medicine, P.C.
- Robert Wood Johnson Medical School
- NYU School of Medicine's Kaplan Comprehensive Cancer Center
- Veterans Affairs Medical Center - Durham
- Duke Comprehensive Cancer Center
- Simmons Cancer Center - Dallas
- University of Texas Medical Branch
- Massey Cancer Center