Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture
Patients Undergoing Puncture of the Bone Marrow
About this trial
This is an interventional prevention trial for Patients Undergoing Puncture of the Bone Marrow focused on measuring Bone marrow puncture, Pain
Eligibility Criteria
Inclusion Criteria: Patients scheduled for both first or repeated punction of the bone marrow Age between 18 and 85 years Written informed consent Exclusion Criteria: Contraindication for a punction of the bone marrow Administration of benzodiazepines or analgetic drugs prior to the bone marrow punction Known hypersensitivity to benzodiazepines or Piritramid Known contraindication to benzodiazepines (Myasthenia gravis in particular) or Piritramid (Pheochromocytoma or conditions affecting the consciousness) Poor general condition (ECOG Performance Status 3,4; Karnofsky Index < 50%) Addictive disorders Administration of antidepressive drugs Administration of drugs that potentially depress the respiratory function Severe cardio-circulatory or respiratory insufficiency, sleep apnea syndrome Known bradycardia History of syncope(s) of unclear etiology Pregnancy or lactation
Sites / Locations
- Medizinische Klinik und Poliklinik I, University Clinic Carl Gustav Carus