Complete Decongestive Therapy With Negative Pressure for Lipedema and Lymphedema Therapy
Lipedema, Secondary Lymphedema
About this trial
This is an interventional treatment trial for Lipedema focused on measuring lipedema, lymphedema, therapy, sodium, swelling
Eligibility Criteria
Inclusion Criteria:
- Females with a diagnosis of lipedema or a probable diagnosis of lipedema
- Females with a diagnosis of secondary limb lymphedema following cancer treatments
Exclusion Criteria:
- Subjects who have any type of non-MRI compatible bioimplant activated by mechanical, electronic, or magnetic means (e.g., cochlear implants, pacemakers, neurostimulators, biostimulators, electronic infusion pumps, etc.) or are not able to comfortably be able to tolerate the limited fit of the MRI
- Subjects who have any type of ferromagnetic bioimplant that could potentially be displaced.
- Subjects who may have shrapnel imbedded in their bodies (such as from war wounds), metal workers and machinists (potential for metallic fragments in or near the eyes).
- Pregnant women will be excluded from the MRI portion of the study only
- Subjects who have open wounds on either ankle or top of foot because of contraindications with placement of electrodes to obtain the L-DEX U400 readings.
- Persons with heart pacemakers.
- Persons with Dercum's disease, diabetes or high blood pressure (systolic great than 140 and diastolic great than 90).
Sites / Locations
- Vanderbilt University Medical Center
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Patients with Lipedema
Patients with secondary leg lymphedema
Females with lipedema who meet the inclusion and exclusion criteria for lipedema and this study requirements. The intervention in this arm is a course of CDT with graded negative pressure.
Patients with secondary leg lymphedema following cancer therapies will be limited to the female gender since the comparison group of patients have lipedema which is a condition predominantly effecting females. These patient subjects will consist of those who meet the inclusion and exclusion criteria for secondary leg lymphedema and this study requirements. The intervention in this arm is a course of CDT with graded negative pressure.