Conventional Oxygen Therapy Versus Continuous Transnasal High Flow Oxygen Therapy for Head and Neck Diagnostic Panendoscopy Under General Anesthesia in Spontaneous Ventilation (OPTINOSE)

Inclusion Criteria: Patients suffering from a head and neck cancer, most often tumor of the bucco-pharyngo-laryngeal cavities, having to carry out a diagnostic HN panendoscopy; Patient over 18 years of age; ASA < 4; BMI ≤ 45; Patient willing and able to provide written informed consent for the trial;; Patient affiliated with a health insurance system. Exclusion Criteria: Patient with a contraindication to the Optiflow™ system as defined in the manufacturer's brochure; Patient with a tumor obstructing more than 80% of the glottic lumen; Patient with impossible intubation criteria: Mallampati 4 and mouth opening less than 20 mm Retrognathia Patient with: A known intracranial pathology; Documented pulmonary hypertension; Uncontrolled epilepsy; Uncontrolled heart rhythm disorder; Pulmonary pathology with hypoxemia: Spo2 <92% in ambient air; Patient at high risk of a full stomach evaluated by the anesthetist; ASA ≥ 4 Morbid obesity with BMI> 45; Obstructive upper airway tumor with functional impact; Known contraindication to propofol or alfentanil; Panendoscopy procedure to be combined with an oesogastro-duodenal fibroscopy; Vulnerable persons as defined by articles 64 and 68 of Regulation (EU) 2017/745 of the European Parliament and of the Council of 5 April 2017 on medical devices : In the case of incapacitated subjects who have not given, or have not refused to give, informed consent before the onset of their incapacity, a clinical investigation may be conducted only where, in addition to the conditions set out in Article 62(4) Pregnant or breast-feeding women who do not fall under the provisions of Article 66 Adults subject to a legal protection order or unable to give their consent.