Cord Milking and Activity Of The Immune System In Preterm Infants

In the embry life there is a passage of IgG type, from the mother to tha embryoyo and only in the age of 3-5 month after birth the infant start to develop them by himself. In preterm infants the starting point of the level of the IgG's is lower from the level of term infants. Delayed cord clamping /milking it was prooved in many researches as benificial in terms of : levels of hemoglobin; hematocrit and feritin in the neonats. Also benefits were proved by means of less need for blood tranfusion, less intra ventricular hemorrhage; necrotzing entero colitis and iron deficiency anemia. The hypothesis is that delayed clamping /milking it will increse the level of IgG's in preterm infants. The end point hypothesis is that delayed cord clamping /milking cause to less fever disease or hospitalization it the neonats.

In this study we come to a prove that if we miking the cord in preterm infats we will increse the level of IgG .

Blood test for IgG's level from the baby in : at delivery . 24 hours after delivery. before discharg from hospital

Mother's telephone questioning about the infant disease: fiver / hospitalization/tretment wit antibiotic.

Phone call interview of the mother in 3 and 6 month from delivery about : emergengy room admission; hospitalization, fever disease and antibiotic treatment in this time period.

Inclusion Criteria: PRETERM INFANS BETWEEN 24+0/7 TO 36 6/7 WEEKS. NEWBORN FOR MOTHER WHO AGREE TO PARTICIPATE IN THE RESEARCH WHO DELIVER IN NORMAL DELIVERY / PLANED OR URGENT CESARIAN DELIVERY Exclusion Criteria: INTRA UTERINE GROWTH RESTRICTION, INFANT UNDER 10% TO AGE OF PREGNANCY. MOTHER WHO IS NOT WILLING TO PARTICIPATE IN RESEARCH. NEONATES TO MOTHER WHOM SUSPECTED TO BE IMMUNO- COMPROMISED OR HAVING INFECTION AROUND DELIVERY.