Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI
Gulf War Syndrome
About this trial
This is an interventional treatment trial for Gulf War Syndrome focused on measuring Gulf War Illness, Botanicals, Remote, Clinical Trial
Eligibility Criteria
Inclusion Criteria:
- Meets Kansas GWI Case Definition
- Meets CDC GWI Case Definition
- Able to commit to a 10-month study
Exclusion Criteria:
- Currently involved in an experimental treatment study
- Abnormal liver function values
- Abnormal kidney function values
- Currently pregnant
- Blood clotting disorder (contraindicated with all three botanicals)
- Antiplatelet or anticoagulant medication use (contraindicated with all three botanicals)
Sites / Locations
- The University of Alabama at BirminghamRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
Gulf War Veterans, Curcumin
Gulf War Veterans, Resveratrol
Gulf War Veterans, Stinging Nettle
All GWI Veterans will undergo the same screening and experimental procedures. Participants must meet both the Kansas and CDC (Centers for Disease Control and Prevention) Case Definitions of GWI. Participants must have been deployed to the Persian Gulf Region during the 1990-1991 Gulf War, meet symptom domain criteria, and not have exclusionary medical conditions. The case definitions will be used for inclusionary screening purposes. This trial tests three interventions, which are all tested independently. Participants will receive only one of the three interventions. The curcumin, resveratrol, and stinging nettle trials all follow the same design and procedures. Participants will complete one month of baseline, eight months of capsules, and one month of endline measurements.
All GWI Veterans will undergo the same screening and experimental procedures. Participants must meet both the Kansas and CDC (Centers for Disease Control and Prevention) Case Definitions of GWI. Participants must have been deployed to the Persian Gulf Region during the 1990-1991 Gulf War, meet symptom domain criteria, and not have exclusionary medical conditions. The case definitions will be used for inclusionary screening purposes. This trial tests three interventions, which are all tested independently. Participants will receive only one of the three interventions. The curcumin, resveratrol, and stinging nettle trials all follow the same design and procedures. Participants will complete one month of baseline, eight months of capsules, and one month of endline measurements.
All GWI Veterans will undergo the same screening and experimental procedures. Participants must meet both the Kansas and CDC (Centers for Disease Control and Prevention) Case Definitions of GWI. Participants must have been deployed to the Persian Gulf Region during the 1990-1991 Gulf War, meet symptom domain criteria, and not have exclusionary medical conditions. The case definitions will be used for inclusionary screening purposes. This trial tests three interventions, which are all tested independently. Participants will receive only one of the three interventions. The curcumin, resveratrol, and stinging nettle trials all follow the same design and procedures. Participants will complete one month of baseline, eight months of capsules, and one month of endline measurements.