DCB Under the Guidance of OCT in STEMI
Acute ST-segment Elevation Myocardial Infarction
About this trial
This is an interventional treatment trial for Acute ST-segment Elevation Myocardial Infarction
Eligibility Criteria
Inclusion Criteria: Age 18-75 Definitely diagnosed as acute ST segment elevation myocardial infarction according to diagnostic criteria Time of onset ≤ 12h Voluntary signing of informed consent After pretreatment, the culprit vessel participates in stenosis ≤ 30%, no type C (or OCT shows that the dissection involves the middle membrane, and the angle is ≥ 90 degrees) or above, no hematoma, and no obvious thrombus (TIMI thrombus load rating ≤ 2) Exclusion Criteria: Time of onset>12h Those who are allergic to contrast agents, aspirin tablets and Tigrilol tablets; Active bleeding or recent bleeding history Cardiogenic shock and long-term cardiopulmonary resuscitation; The life span is expected to be less than 12 months Angiography showed left main trunk lesion; Angiography shows patients with in stent restenosis Patients who the investigator thinks may affect the normal progress of the study or cannot cooperate well with the study or may cause obvious risks, such as alcoholics or drug abusers, cancer, serious liver, kidney, lung, endocrine (such as uncontrolled diabetes or thyroid disease), nervous or blood system diseases; Known or suspected pregnancy (baseline ß - hCG pregnancy test must be conducted for women in childbearing period), women in menstrual period. The criminal blood vessel has C-type or above dissection after pretreatment, and there is coronary hematoma. After pretreatment, criminal vessels still have obvious thrombus residues (TIMI thrombus load grade ≥ 3) OCT confirms that the criminal lesion is caused by plaque erosion
Sites / Locations
- Fuwai Central China Cardiovascular HospitalRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Experimental group
Control group
Drug-coated Balloon (Lepu Medical Technology (Beijing) Co.,Ltd.)
Drug Eluting Stent(Microport Medical)