Deprescribing Tamsulosin in Older Men (PERSONAL)
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
About this trial
This is an interventional treatment trial for Benign Prostatic Hyperplasia
Eligibility Criteria
Inclusion Criteria:
- Urology patient at UCSF
- Must own Android or iPhone smartphone, tablet, or computer
- Taking tamsulosin for urinary-related symptoms
- Able to speak and read English
- Male 55-80 years old of age at telephone screening.
- Written informed consent (and assent when applicable) obtained from subject or subject' s legal representative and ability for subject to comply with the requirements of the study.
- Willing to receive electronic PERSONAL daily intake surveys for 3 months
- Willing to self-report urinary symptom or medication side effect data at specified frequency.
- Have home WiFi access.
- Patients with h/o prostate cancer may be enrolled but is not required
- Patients with h/o kidney stones may be enrolled but is not required
Exclusion Criteria:
- Taking tamsulosin for <12 months.
- International Prostate Symptom Score <5 or >25
- Current participation in any other mobile app-based clinical study.
- Planning to relocate from area within the study duration.
- Impaired vision that could limit the use of the mobile apps (participant-reported)
Sites / Locations
- University of California, San Francisco
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Tamsulosin 0.4 mg or 0.8 mg, Then Placebo
Placebo, Then Tamsulosin 0.4 mg or 0.8 mg
Participants first received Tamsulosin 0.4 mg or 0.8 mg taken daily in 2 week treatment periods, 4 treatment periods in 12 weeks. After a washout period of 1 week, the participants then received Placebo tablet taken daily in 2 week treatment periods, 4 treatment periods in 12 weeks.
Participants first received Placebo tablet taken daily in 2 week treatment periods, 4 treatment periods in 12 weeks. After a washout period of 1 week, the participants then received Tamsulosin 0.4 mg or 0.8 mg taken daily in 2 week treatment periods, 4 treatment periods in 12 weeks.