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Depression Prevention Program for Adolescents

Primary Purpose

Depression

Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Cognitive behavior therapy (CBT)
Supportive/expressive (S/E) therapy
Bibliotherapy
Sponsored by
University of Texas at Austin
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional prevention trial for Depression focused on measuring Adolescent, CBT

Eligibility Criteria

14 Years - 18 Years (Child, Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria: Beck Depression Inventory score higher than 10 Parent or guardian willing to provide informed consent Exclusion Criteria: Diagnosis of depression

Sites / Locations

  • University of Texas at Austin

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm Type

Experimental

Active Comparator

Active Comparator

No Intervention

Arm Label

1

2

3

4

Arm Description

Participants will receive cognitive behavioral therapy

Participants will receive supportive/expressive therapy

Participants will receive bibliotherapy

Participants in the control condition will receive no treatment

Outcomes

Primary Outcome Measures

Depressive symptoms

Secondary Outcome Measures

Full Information

First Posted
September 13, 2005
Last Updated
April 23, 2012
Sponsor
University of Texas at Austin
Collaborators
National Institute of Mental Health (NIMH)
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1. Study Identification

Unique Protocol Identification Number
NCT00183417
Brief Title
Depression Prevention Program for Adolescents
Official Title
Depression Prevention Program for High-Risk Adolescents
Study Type
Interventional

2. Study Status

Record Verification Date
April 2012
Overall Recruitment Status
Completed
Study Start Date
September 2004 (undefined)
Primary Completion Date
May 2009 (Actual)
Study Completion Date
May 2009 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University of Texas at Austin
Collaborators
National Institute of Mental Health (NIMH)

4. Oversight

5. Study Description

Brief Summary
This study will compare the effectiveness of two programs designed to prevent depression in adolescents.
Detailed Description
Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents. This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Depression
Keywords
Adolescent, CBT

7. Study Design

Primary Purpose
Prevention
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
350 (Actual)

8. Arms, Groups, and Interventions

Arm Title
1
Arm Type
Experimental
Arm Description
Participants will receive cognitive behavioral therapy
Arm Title
2
Arm Type
Active Comparator
Arm Description
Participants will receive supportive/expressive therapy
Arm Title
3
Arm Type
Active Comparator
Arm Description
Participants will receive bibliotherapy
Arm Title
4
Arm Type
No Intervention
Arm Description
Participants in the control condition will receive no treatment
Intervention Type
Behavioral
Intervention Name(s)
Cognitive behavior therapy (CBT)
Intervention Description
Participants will complete worksheets and group discussion on how to increase positive mood and activity.
Intervention Type
Behavioral
Intervention Name(s)
Supportive/expressive (S/E) therapy
Intervention Description
Participants will be encouraged to express feelings and emotions without advice giving.
Intervention Type
Behavioral
Intervention Name(s)
Bibliotherapy
Intervention Description
Participants will be given a book on how to increase their mood.
Primary Outcome Measure Information:
Title
Depressive symptoms
Time Frame
Measured at Year 1

10. Eligibility

Sex
All
Minimum Age & Unit of Time
14 Years
Maximum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Beck Depression Inventory score higher than 10 Parent or guardian willing to provide informed consent Exclusion Criteria: Diagnosis of depression
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Eric M. Stice, PhD
Organizational Affiliation
University of Texas at Austin
Official's Role
Principal Investigator
Facility Information:
Facility Name
University of Texas at Austin
City
Austin
State/Province
Texas
ZIP/Postal Code
78712
Country
United States

12. IPD Sharing Statement

Citations:
PubMed Identifier
22414236
Citation
Gau JM, Stice E, Rohde P, Seeley JR. Negative life events and substance use moderate cognitive behavioral adolescent depression prevention intervention. Cogn Behav Ther. 2012;41(3):241-50. doi: 10.1080/16506073.2011.649781. Epub 2012 Mar 13.
Results Reference
derived

Learn more about this trial

Depression Prevention Program for Adolescents

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