Diabetes Prevention Program Outcomes Study (DPPOS)
Diabetes Mellitus, Cancer, CVD
About this trial
This is an interventional prevention trial for Diabetes Mellitus focused on measuring DPP, IGT, Prediabetes, Type 2 diabetes, Macrovascular disease, Microvascular disease, Lifestyle, Metformin, Obesity
Eligibility Criteria
Participation as a volunteer in the Diabetes Prevention Program (DPP).
Sites / Locations
- George Washington University
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Active Comparator
Placebo Comparator
1 Original Lifestyle
2 Original Metformin
3 Original Placebo
randomized to unmasked Intensive Lifestyle during the DPP and offered Intensive Lifestyle Group Session, DPPOS Group Lifestyle plus DPPOS Boost Lifestyle sessions in DPPOS Phase 1 and 2
randomized to the masked metformin treatment group during DPP and continued open label in DPPOS. Participants were also offered Intensive Lifestyle Group Session, DPPOS Group Lifestyle in DPPOS Phase 1 and 2.
randomized to masked placebo during DPP and offered Intensive Lifestyle Group Session, DPPOS Group Lifestyle in DPPOS Phase 1 and 2