Dietary Supplements for COVID-19
Covid19
About this trial
This is an interventional treatment trial for Covid19 focused on measuring Natural Health Products, NHP, Dietary Supplements, Vitamin C, Vitamin D, Vitamin K, Zinc, COVID-19, SARS-CoV-2
Eligibility Criteria
Inclusion Criteria:
- Adults (≥18) who test positive for SARS-CoV-2 in an outpatient setting
- Access to internet
Exclusion Criteria:
- Symptom onset greater than 4 days prior to enrolment
- Supplementing regularly with >500 mg vitamin C, >1000 units vitamin D, >120 mcg vitamin K (any form), or >15 mg zinc taken daily within the past month
- Currently taking warfarin or an equivalent vitamin K antagonist anticoagulant
- End stage chronic kidney disease
- History of calcium oxalate kidney stones
- Active granulomatosis (sarcoidosis, tuberculosis, lymphoma)
- Known hypercalcemia or hypervitaminosis D
- Currently taking either of the following antibiotics: cephalexin, tetracyclines
- Participating in an investigational study or participation in an investigational study within the past 30 days
- Any reason which, under the discretion of the qualified investigator or delegate, would preclude the patient from participating.
Sites / Locations
- The Centre for Health Innovation
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Treatment
Control
Specific Product: Vitamin D3 50,000 IU Formulation: Capsule. Each capsule will contain 500 mg (50,000 units) cholecalciferol (vitamin D3) Dose: One capsule on day 1 of the intervention period Specific Product: Vitamin K2/D Formulation: Liquid. Each 0.0285 mL drop contains 30 mcg menaquinone-7 (MK-7, vitamin K2) and 3.125 mcg (125 units) cholecalciferol (vitamin D3). Dose: 0.114 mL (four drops) twice daily for 21 days totalling 240mcg MK-7 and 1,000 units cholecalciferol per day. Specific Product: Vitamin C/Zinc Formulation: Capsule. Each capsule will contain 666 mg ascorbic acid (vitamin C) and 8.3 mg of zinc acetate Dose: Three capsules three times daily for 21 days totalling 6 g ascorbic acid and 75 mg zinc acetate per day.
Specific Product: Vitamin D3 50,000 IU Placebo Equivalent: microcrystalline cellulose capsule, 350 mg Specific Product: Vitamin K2/D Placebo Equivalent: Medium chain triglyceride oil Specific Product: Vitamin C/Zinc Placebo Equivalent: microcrystalline cellulose capsule, 350 mg