Direct Comparison of TG and WFO LASIK

To compare the efficacy to different profiles, direct head-to-head studies had been conducted. In one previous review study revealed that TG LASIK provided patient with better uncorrected visual acuity (UCVA) than WFO LASIK and WFG LASIK. In recent previous contralateral eye studies also showed that TG LASIK induced less postoperative higher-order aberration than WFO LASIK. However, these studies included only low-to-moderate myopia patients, for patients with high myopia (spherical equivalent > 6D), the effect of TG LASIK comparing with WFO LASIK had not been reported before. The aim of our study is to analyze and compare the visual performance of TG LASIK and WFO LASIK in high myopia and low-to-moderate myopia patients, , particularly UCVA, corrected distance visual acuity (CDVA), contrast sensitivity (CS), and wavefront aberration.

A 11-item questionnaire, item scores range from 0 to 10 and higher item scores in questionnaire indicated more difficulty in achieving specific visual tasks

Inclusion Criteria: age between 20 and 50 years old CDVA of both eyes could reach 0.1 logarithm of the minimum angle of resolution (logMAR) stable refractive errors of myopia and astigmatism Exclusion Criteria: cataract corneal opacities or irregularities dry eye (Schirmer's test I ≤ 5mm) amblyopia coexisting ocular pathologies glaucoma non-dilating pupil history of intraocular surgery, laser therapy, or retinopathy optic nerve or macular diseases estimated postoperative cornea residual stromal thickness less than 250 μm pregnancy or under lactation uncontrolled diabetic mellitus or systemic immune disease refusal or unable to maintain follow-up

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