Directly Observed Therapy for HIV Infected Adolescents
HIV Infections
About this trial
This is an interventional treatment trial for HIV Infections focused on measuring Treatment Experienced, Adherence, Compliance, Directly Observed Therapy, DOT, Treatment Naive
Eligibility Criteria
Inclusion Criteria: Infected with HIV after age 12 Initiating, continuing, changing, or reinitiating a daily or twice-daily HAART regimen AND have demonstrated adherence problems (less than 85% of prescribed doses taken, as clinically disclosed, on 2 consecutive occasions at least 1 month apart). More information on this criterion can be found in the protocol. Able and willing to swallow medication Have access to HAART Parent or guardian willing to provide informed consent, if applicable Willing to use acceptable forms of contraception Exclusion Criteria: Clinically significant diseases other than HIV infection or clinically significant findings during screening or physical examination that, in the opinion of the investigator, would require much closer follow-up and frequent monitoring than would be generally done for other HIV infected patients of comparable age HAART regimens that include medications taken more often than twice-daily Investigational agents (HAART or other medications) administered as part of other clinical trials Pregnant or breastfeeding
Sites / Locations
- Childrens Hospital Los Angeles
- Los Angeles County Medical Center/USC
- UCSD Mother, Child & Adolescent HIV Program
- Childrens Hospital of Michigan
- University of Rochester Medical Center
- St. Jude Childrens Research Hospital, Memphis