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Dispatcher-Assisted Resuscitation Trial (DART)

Primary Purpose

Heart Arrest

Status
Completed
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
dispatcher-assisted CPR with compressions & ventilations
dispatcher-assisted CPR instructions with compressions only
Sponsored by
Public Health - Seattle and King County
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Heart Arrest focused on measuring Heart arrest, Cardiopulmonary resuscitation, Dispatcher

Eligibility Criteria

9 Years - undefined (Child, Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Cardiac arrest events where CPR is not ongoing but a bystander is willing to attempt with assistance Exclusion Criteria: Pregnancy Prisoners Cardiac arrest due to asphyxia, drowning, hanging, or electrocution

Sites / Locations

  • Thurston County Dispatch
  • Division of Emergency Medical Services, Public Health - Seattle and King County
  • London Ambulance Service

Arms of the Study

Arm 1

Arm 2

Arm Type

Active Comparator

Active Comparator

Arm Label

1

2

Arm Description

When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions only

When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions and breaths

Outcomes

Primary Outcome Measures

Survival to hospital discharge
assessed at hospital discharge

Secondary Outcome Measures

Neurological status at hospital discharge
assessed at hospital discharge

Full Information

First Posted
September 13, 2005
Last Updated
October 28, 2014
Sponsor
Public Health - Seattle and King County
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1. Study Identification

Unique Protocol Identification Number
NCT00219687
Brief Title
Dispatcher-Assisted Resuscitation Trial (DART)
Official Title
Randomized Trial of Dispatcher-Assisted CPR:Chest Compression Alone Versus Chest Compression Plus Ventilation
Study Type
Interventional

2. Study Status

Record Verification Date
October 2014
Overall Recruitment Status
Completed
Study Start Date
June 2004 (undefined)
Primary Completion Date
August 2012 (Actual)
Study Completion Date
August 2012 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Public Health - Seattle and King County

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital cardiac arrests.
Detailed Description
Out-of-hospital cardiac arrest, a condition characterized by a person suddenly collapsing due to heart stoppage, is a leading cause of death in the United States. In out-of-hospital cardiac arrest, survival is dependent upon what the American Heart Association has termed the chain of survival which includes quick activation of the 9-1-1 system, prompt cardiopulmonary resuscitation (CPR), early defibrillation, and qualified advanced life support care (paramedic care). CPR allows for some circulation and delivery of oxygen to vital organs when the heart is no longer beating on its own. However, in some instances, the citizen bystander has not been trained in CPR, presenting a circumstance where the cardiac arrest victim may not receive CPR until the arrival of emergency medical services (EMS) personnel (i.e., paramedics). The delay in CPR adversely affects outcome and dcreases the chance of survival. In response to this need, the EMS Division of Public Health - Seattle and King County developed and instituted telephone CPR instructions that could be provided "on-the-spot" during a cardiac arrest by the emergency medical (9-1-1) dispatcher. The instructions are designed to be given over the phone to persons who have not had previous CPR training so that they can initiate CPR prior to the arrival of EMS personnel and have been termed "dispatcher-assisted" CPR. The dispatcher instructions provided by the dispatch agencies of King County include the standard "full" CPR protocol of ventilations (breathing into the victim's mouth to inflate the lungs) and chest compressions(pumping on the patients chest to help circulate the blood). The ventilations oxygenate the blood while the chest compressions pump the oxygenated blood forward. This EMS program has led to a considerable increase in the proportion of cardiac arrest victims in King County that receive citizen bystander CPR prior to EMS arrival and has been associated with improved survival (appendix 1). Comparison: Dispatcher-assisted CPR instructions with compressions and ventillations compared to dispatcher-assisted CPR instructions with compressions only.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Heart Arrest
Keywords
Heart arrest, Cardiopulmonary resuscitation, Dispatcher

7. Study Design

Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
5494 (Actual)

8. Arms, Groups, and Interventions

Arm Title
1
Arm Type
Active Comparator
Arm Description
When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions only
Arm Title
2
Arm Type
Active Comparator
Arm Description
When a 911 call is determined to be a cardiac arrest, the caller reporting the event who needs or desires instructions to perform CPR while waiting for EMS to arrive will receive dispatcher-assisted CPR instructions with chest compressions and breaths
Intervention Type
Other
Intervention Name(s)
dispatcher-assisted CPR with compressions & ventilations
Intervention Description
Delivery of telephone CPR instructions to lay callers with chest compressions and ventilations when the patient is identified to be in cardiac arrest
Intervention Type
Other
Intervention Name(s)
dispatcher-assisted CPR instructions with compressions only
Intervention Description
Delivery of telephone CPR instructions to lay callers with hands-only chest compressions when the patient is identified to be in cardiac arrest
Primary Outcome Measure Information:
Title
Survival to hospital discharge
Description
assessed at hospital discharge
Time Frame
varied
Secondary Outcome Measure Information:
Title
Neurological status at hospital discharge
Description
assessed at hospital discharge
Time Frame
varied

10. Eligibility

Sex
All
Minimum Age & Unit of Time
9 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Cardiac arrest events where CPR is not ongoing but a bystander is willing to attempt with assistance Exclusion Criteria: Pregnancy Prisoners Cardiac arrest due to asphyxia, drowning, hanging, or electrocution
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Thomas D Rea, MD, MPH
Organizational Affiliation
Division of Emergency Medical Services, Public Health - Seattle and King County
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Mickey S Eisenberg, MD, PhD
Organizational Affiliation
Division of Emergency Medical Services, Public Health - Seattle and King County
Official's Role
Principal Investigator
Facility Information:
Facility Name
Thurston County Dispatch
City
Olympia
State/Province
Washington
Country
United States
Facility Name
Division of Emergency Medical Services, Public Health - Seattle and King County
City
Seattle
State/Province
Washington
ZIP/Postal Code
98104
Country
United States
Facility Name
London Ambulance Service
City
London
State/Province
England
Country
United Kingdom

12. IPD Sharing Statement

Citations:
PubMed Identifier
20818863
Citation
Rea TD, Fahrenbruch C, Culley L, Donohoe RT, Hambly C, Innes J, Bloomingdale M, Subido C, Romines S, Eisenberg MS. CPR with chest compression alone or with rescue breathing. N Engl J Med. 2010 Jul 29;363(5):423-33. doi: 10.1056/NEJMoa0908993.
Results Reference
derived

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Dispatcher-Assisted Resuscitation Trial (DART)

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