Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled Study
Preterm Premature Rupture of Membranes
About this trial
This is an interventional prevention trial for Preterm Premature Rupture of Membranes
Eligibility Criteria
Inclusion Criteria:
Patients with a single nonanomalous fetus and PPROM at ≥ 24.0 and ≤ 34.0 weeks' gestation.
Exclusion Criteria:
fetus with anomalies, chorioamnionitis, experienced PPROM within 14 days of either amniocentesis or cervical cerclage placement, multiple gestation, obstetrical indication for immediate delivery, delivery within 24 h of admission intrauterine fetal death at the time of presentation.
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Sites / Locations
- Bakırkoy Women and Children Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
vitaminCE
no drug
Eligible and consenting women were randomly assigned to capsules containing a combination of 1,000 mg vitamin C (ascorbic acid) and 400 international units of vitamin E (RRR alpha tocopherol acetate)
no drug