Doxycycline to Treat Mansonella Perstans Infection in Patients With and Without Lymphatic Filariasis
Mansonella Perstans Infection, Mp Microfilaremia
About this trial
This is an interventional treatment trial for Mansonella Perstans Infection focused on measuring Parasite, Chemotherapy, Wuchereria Bancrofti
Eligibility Criteria
INCLUSION CRITERIA - SCREENING: Age 14 to 65. Both genders. Not pregnant or breastfeeding by history. EXCLUSION CRITERIA - SCREENING: Non-volunteers. Age less than 14 or greater than 65. Pregnant or breastfeeding by history. INCLUSION CRITERIA - TREATMENT: Age 14 to 65 years. Men and non-pregnant or breastfeeding women. EXCLUSION CRITERIA - TREATMENT: Non-volunteers. Age less than 14 or greater than 65. Pregnancy or breast-feeding. Hgb less than or equal to 10 g/dl. Cr greater than 1.4/100 ml. ALT greater than 45 U or bilirubin greater than 1.5. Weight less than 40 kg. Heavy alcohol use (more than 1 beer or other alcohol-containing drink/day). Temperature greater than 37.5C or other serious medical illnesses. History of allergy to doxycycline or other tetracyclines. History of HIV infection or other immunocompromised state.
Sites / Locations
- National Institute of Allergy and Infectious Diseases (NIAID), 9000 Rockville Pi