Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer
Breast Cancer
About this trial
This is an interventional diagnostic trial for Breast Cancer focused on measuring breast cancer
Eligibility Criteria
DISEASE CHARACTERISTICS: Diagnosis of cellular atypia in nipple aspirate or ductal lavage fluid Enrollment on RMNHS-2242 or RMNHS-2269 required No inflammatory breast cancer Hormone receptor status: Not specified PATIENT CHARACTERISTICS: Age 18 to 64 Sex Female Menopausal Status Any status Performance status Not specified Life expectancy Not specified Hematopoietic Not specified Hepatic Not specified Renal Not specified Other No prior allergy to eutectic mixture of local anesthetics (EMLA®) cream or lidocaine No severe illness that would preclude study participation No mental illness or handicap that would preclude study compliance No active infection or inflammation in the breast being studied No nursing within the past 12 months Not pregnant Not unconscious PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy Not specified Endocrine therapy No prior tamoxifen Radiotherapy Not specified Surgery No prior subareolar surgery (e.g., papilloma resections, biopsies, or fine needle aspirations) or any other surgery that may disrupt the ductal systems within 2 cm of the nipple Biopsies and fine needle aspirations > 2 cm from the nipple are allowed No prior breast implantation on proposed lavage side Other No prior chemopreventative agents
Sites / Locations
- Royal Marsden - LondonRecruiting