Eating Concerns and Compulsivity
Anorexia Nervosa in Remission, Eating Disorder
About this trial
This is an interventional basic science trial for Anorexia Nervosa in Remission focused on measuring Computational
Eligibility Criteria
Inclusion Criteria:
- Participant is willing and able to give informed consent for participation in the study.
- Females aged 18 to 45 years.
- BMI over 18.5 and has remained so for the last year.
- Participant is a fluent English speaker. Inclusion: recovered from anorexia
- Past formal diagnosis of AN (defined by DSM-5 criteria).
- Fully recovered: Score must be below 2.767 on the EDE-Q, below 16 on the CIA, and below 20 on the EAT-26 or partially recovered: scores may be above 2.767, 16 and 20 respectively.
Inclusion: high scoring on EAT-26
- Score above 20 on the EAT-26 questionnaire. Inclusion: healthy control
- Score below 2.767 on the EDE-Q, below 16 on the CIA, and below 20 on the EAT-26.
Exclusion Criteria:
- Any current diagnosis of a psychiatric disorder which in the investigator's opinion could impact study results (e.g. significant depression, anxiety or OCD).
- Any current psychotropic medications.
- Current regular cigarette smoking of over 5 cigarettes per day.
- Recent use of illicit drugs.
- Alcohol intake which indicates an element of alcohol abuse; or unwillingness to refrain from drinking the night before the study visit.
Exclusion for high scoring EAT-26
• A former formal diagnosis of an eating disorder. Note that in this group a current diagnosis of EDNOS will not be an exclusion criterion.
Sites / Locations
- Department of Psychiatry, University of Oxford
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
Recovered from anorexia nervosa
High scoring on the EAT-26
Healthy controls
Those who have a past diagnosis of AN (defined by the Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) criteria) but are currently recovered, as shown by BMI over 18.5 throughout the last 12 months (self-report and current weight measured). Defined as either 'fully recovered'and: score must be within the 'normal range' of the Eating Disorders Examination Questionnaire (EDE-Q) global mean scores for young women, below 20 on the EAT-26 and below 16 on the Clinical Impairment Assessment for Eating Disorders (CIA); or partially recovered where one or more of these scores may be above the above-mentioned cutoffs.
Those who score above 20 on the EAT-26, but who do not declare a former diagnosis of an eating disorder (though they may meet criteria for a current diagnosis during the Structured Clinical Interview for the DSM-5).
No history of or current diagnosis of any psychiatric disorder (especially eating disorders) which could impact study results.