Effect of Locally Applied Hyaluronic Acid, Mixed With Autogenous Demineralized Tooth Graft, for Socket Preservation, Versus Autogenous De-mineralized Tooth Graft.
Alveolar Bone Resorption, Socket Preservation, Bone Resorption
About this trial
This is an interventional treatment trial for Alveolar Bone Resorption
Eligibility Criteria
Inclusion Criteria: 1. 18 years old or older. 2. Requiring alveolar preservation after tooth extraction prior to placement of dental implant. 3. Participants that are eligible for immediate implantation, yet having factors that are hindering these patients from immediate placement of an implant at the time of extraction (ex: Financial related factors - psychological factors - time related factors). 4. Motivated patients with good enough understanding of oral health measurements and importance. 5. Sufficient keratinized gingiva to cover the grafted bone. 6. The presence of dentition adjacent to the bone defect. 7. Patients who are healthy or have well-controlled systemic disease(s). 8. Teeth extractions are to be recommended due to trauma, caries, or periodontal diseases. * 9. Single rooted teeth from both arches. 10. No acute infections, pus formation, socket and bony discharges. 11. Hopeless teeth, to be extracted, are bounded both mesially and distally by adjacent, teeth. 12. Intact buccal bone of the teeth to be extracted. Exclusion Criteria: 1. Heavy smokers (more than 10 cigarettes per day or an electronic cigarette dose of >6 mg/ml of nicotine). 2. Presence of active infection or severe inflammation in the intervention zone. 3. Relevant medical history that contraindicates implant surgery. 4. Immunosuppression (eg. Hiv, solid-organ transplants). 5. Head and neck-irradiated patients in the past 5 years. 6. Regular intake of bisphosphonates, anticoagulants, or anti-inflammatories. 7. Chronic drug abuse or alcoholic habits. 8. Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score >15%) and lack of motivation. 9. Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%). 10. Uncontrolled and /or untreated periodontal disease. 11. Patients who had previously received bone graft on the site to be operated. 12. Patients with significant comorbidity such as recent heart attack or coagulation disorder. 13. Pregnant subjects.
Sites / Locations
- Cairo universityRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
tooth extraction and socket preservation with demineralized tooth graft
tooth extraction and socket preservation with demineralized tooth graft and hyaluronic acid