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Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease

Primary Purpose

Chronic Obstructive Pulmonary Disease

Status
Completed
Phase
Not Applicable
Locations
Brazil
Study Type
Interventional
Intervention
Pursed Lips Breathing
Quiet Breathing
Sponsored by
Universidade Federal de Pernambuco
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional supportive care trial for Chronic Obstructive Pulmonary Disease focused on measuring Chronic Obstructive Pulmonary Disease, Respiratory mechanics, Plethysmography, Diaphragm, Respiratory muscles, Breathing exercises

Eligibility Criteria

40 Years - 80 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • COPD diagnosis with stage II-IV (GOLD),
  • Stable clinical condition (no exacerbation or hospital admission in the last four weeks preceding the study)
  • Absence of other disease that may potentially contribute to dyspnea (heart disease, congestive heart failure, neuromuscular diseases, severe postural changes)

Exclusion Criteria:

  • BMI> 30 kg / m2
  • Musculoskeletal limitations
  • Use of oxygen therapy
  • Extreme discomfort during the procedure application

Sites / Locations

  • Clinical Hospital

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Quiet Breathing or Pursed Lips Breathing

Arm Description

Free or natural breathing for six minutes.

Outcomes

Primary Outcome Measures

Chest wall (Analysis of lung volumes)
(L) by plethysmography optoelectronics.
Mobility diaphragmatic (mobility diaphragmatic (mm) by Ultrassonography)
Analysis of mobility diaphragmatic (mm) by Ultrassonography.
Exercise tolerance (Glittre AVD-Test)
Analysis by Glittre AVD-Test (capacity functional test) observing the test execution time (s).

Secondary Outcome Measures

Dyspnea (Borg and MRC Scale)
Assessed by Borg and MRC Scale (Medical Research Council).

Full Information

First Posted
March 5, 2015
Last Updated
April 22, 2015
Sponsor
Universidade Federal de Pernambuco
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1. Study Identification

Unique Protocol Identification Number
NCT02424331
Brief Title
Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease
Study Type
Interventional

2. Study Status

Record Verification Date
April 2015
Overall Recruitment Status
Completed
Study Start Date
March 2014 (undefined)
Primary Completion Date
January 2015 (Actual)
Study Completion Date
March 2015 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Universidade Federal de Pernambuco

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
This study aimed to evaluate the acute effect of PLB technique on diaphragmatic mobility, the kinematics of the thoracoabdominal complex analysis of lung volumes and exercise tolerance in patients with Chronic Obstructive Pulmonary Disease (COPD). This is a study randomized cross-over clinical trial and blind, in subjects with Chronic Obstructive Pulmonary Disease (COPD) according to criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) (FEV1 / FVC <0.7 and FEV1 <80% predicted) selected at the Clinical Hospital of the Federal University of Pernambuco (UFPE) and Otavio de Freitas General Hospital (HGOF). The investigators recruited 13 patients COPD (according to previous sample calculation) aged between 40 and 80 years, of both sexes. The first day was held evaluation of lung function, respiratory muscle strength, body composition, dyspnea index and functional capacity. On the second day was held evaluation of thoracoabdominal complex kinematics by plethysmography Optoelectronics (OEP) with Quiet Breathing (QB) or pursed-lips breathing (PLB). Lung volumes with 2 minutes with QB and 6 minutes PLB or only 6 minutes by QB as randomization were observed. Before and after performing the requested breathing pattern diaphragmatic mobility was observed by Ultrasonography (US) and requested the patient an Inspiratory Capacity maneuver (IC). The evaluator who performed the ultrasound was blinded as to the beginning of the breathing pattern of order performed by the patient.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Chronic Obstructive Pulmonary Disease
Keywords
Chronic Obstructive Pulmonary Disease, Respiratory mechanics, Plethysmography, Diaphragm, Respiratory muscles, Breathing exercises

7. Study Design

Primary Purpose
Supportive Care
Study Phase
Not Applicable
Interventional Study Model
Crossover Assignment
Masking
ParticipantInvestigator
Allocation
Randomized
Enrollment
14 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Quiet Breathing or Pursed Lips Breathing
Arm Type
Experimental
Arm Description
Free or natural breathing for six minutes.
Intervention Type
Other
Intervention Name(s)
Pursed Lips Breathing
Intervention Description
Pursed Lips Breathing for six minutes.
Intervention Type
Other
Intervention Name(s)
Quiet Breathing
Primary Outcome Measure Information:
Title
Chest wall (Analysis of lung volumes)
Description
(L) by plethysmography optoelectronics.
Time Frame
One day during eight minutes
Title
Mobility diaphragmatic (mobility diaphragmatic (mm) by Ultrassonography)
Description
Analysis of mobility diaphragmatic (mm) by Ultrassonography.
Time Frame
One day, before and after eight minutes of pursed lips breathing
Title
Exercise tolerance (Glittre AVD-Test)
Description
Analysis by Glittre AVD-Test (capacity functional test) observing the test execution time (s).
Time Frame
One day, for six minutes approximately. The test will be repeated after 20 minutes of rest.
Secondary Outcome Measure Information:
Title
Dyspnea (Borg and MRC Scale)
Description
Assessed by Borg and MRC Scale (Medical Research Council).
Time Frame
One day, before and after implementation of Glittre-ADL Test

10. Eligibility

Sex
All
Minimum Age & Unit of Time
40 Years
Maximum Age & Unit of Time
80 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: COPD diagnosis with stage II-IV (GOLD), Stable clinical condition (no exacerbation or hospital admission in the last four weeks preceding the study) Absence of other disease that may potentially contribute to dyspnea (heart disease, congestive heart failure, neuromuscular diseases, severe postural changes) Exclusion Criteria: BMI> 30 kg / m2 Musculoskeletal limitations Use of oxygen therapy Extreme discomfort during the procedure application
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Armele D Andrade, Dra
Organizational Affiliation
Universidade Federal de Pernambuco
Official's Role
Study Director
Facility Information:
Facility Name
Clinical Hospital
City
Recife
State/Province
Pernambuco
Country
Brazil

12. IPD Sharing Statement

Learn more about this trial

Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease

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