Effectiveness of Pain Relief Between Adductor Canal Block and Femoral Nerve Block in Total Knee Arthroplasty
Primary Purpose
Osteoarthritis
Status
Unknown status
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Sono guided nerve block
Sponsored by
About this trial
This is an interventional treatment trial for Osteoarthritis
Eligibility Criteria
Inclusion Criteria:
- Patients for total knee arthroplasty having medicare insurance
Exclusion Criteria:
- Alcohol, drug abuser Narcotics addiction
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
Active Comparator
Arm Label
Femoral nerve block
Adductor canal block
Arm Description
Femoral nerve block will be performed just one time after total knee arthroplasty in general anesthesia state
Adductor canal block will be performed just one time after total knee arthroplasty in general anesthesia state
Outcomes
Primary Outcome Measures
Changes in Visual pain scale
Secondary Outcome Measures
Changes in Quadriceps muscle power and strength by cybex muscle testing
Full Information
NCT ID
NCT02513082
First Posted
July 28, 2015
Last Updated
November 3, 2015
Sponsor
The Catholic University of Korea
1. Study Identification
Unique Protocol Identification Number
NCT02513082
Brief Title
Effectiveness of Pain Relief Between Adductor Canal Block and Femoral Nerve Block in Total Knee Arthroplasty
Official Title
Effectiveness of Pain Relief Between Adductor Canal Block and Femoral Nerve Block in Total Knee Arthroplasty in General Anesthesia
Study Type
Interventional
2. Study Status
Record Verification Date
November 2015
Overall Recruitment Status
Unknown status
Study Start Date
August 2015 (undefined)
Primary Completion Date
August 2016 (Anticipated)
Study Completion Date
August 2017 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
The Catholic University of Korea
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
This study aims to compare the effectiveness of adductor canal block and femoral nerve block in total knee arthroplasty in general anesthesia. Two block techniques were proved safe and effective in pain control after total knee arthroplasty. But some authors insist that quadriceps muscle power was decreased by femoral nerve block. The study design is a double-blind randomized controlled trial. Fifty patients planed to undergo simultaneously bilateral total knee arthroplasty are randomised to receive ultrasound-guided femoral nerve block on one leg and adductor canal block on the other, in addition to combined general anaesthesia. The primary outcome was comparative postoperative pain in either extremity at four, eight, 12, 24, 72 hours and 7days postoperatively. Secondary comparative outcomes included motor strength by cybex test.
Detailed Description
Total knee arthroplasty(TKA) is very popular in nowadays. But almost patients complained of postoperative pain and it affect the delay of early mobilization which prevent knee stiffness, lessens hospital stay and improves overall patient satisfaction and outcome of TKA. Intravenous patient-controlled analgesia (PCA) or epidural analgesia is a conventional postoperative analgesia. Recently other block techniques like a adductor canal block and femoral nerve block were known for good methods of pain relief after TKA. However, femoral nerve block reduces quadriceps muscle strength thereby potentially compromising postoperative mobilization. Therefore, it is necessary to evaluate the effectiveness of pain treatment and the preservation of muscle function after the procedure of adductor canal block and femoral nerve block.
The present study aimed to determine and compare the efficacy of adductor canal block and femoral nerve block combined with general anesthesia on (1) postoperative pain control, (2) early patient ambulation and functional recovery and (3) change of muscle power after total knee arthroplasty.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Osteoarthritis
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
ParticipantOutcomes Assessor
Allocation
Randomized
Enrollment
100 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
Femoral nerve block
Arm Type
Experimental
Arm Description
Femoral nerve block will be performed just one time after total knee arthroplasty in general anesthesia state
Arm Title
Adductor canal block
Arm Type
Active Comparator
Arm Description
Adductor canal block will be performed just one time after total knee arthroplasty in general anesthesia state
Intervention Type
Procedure
Intervention Name(s)
Sono guided nerve block
Other Intervention Name(s)
femoral nerve block, adductor canal block
Intervention Description
Sono guided nerve block is effectively and safely performed for pain relief after total knee arthroplasty
Primary Outcome Measure Information:
Title
Changes in Visual pain scale
Time Frame
Changes from the baseline visual pain scale to 1 week after surgery
Secondary Outcome Measure Information:
Title
Changes in Quadriceps muscle power and strength by cybex muscle testing
Time Frame
1 week postoperatively compared to baseline
10. Eligibility
Sex
All
Minimum Age & Unit of Time
19 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Patients for total knee arthroplasty having medicare insurance
Exclusion Criteria:
Alcohol, drug abuser Narcotics addiction
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Yong In, MD, PhD
Phone
8290445228
Email
iy1000@catholic.ac.kr
First Name & Middle Initial & Last Name or Official Title & Degree
Mansoo Kim, MD
Phone
8272333875
Email
kms3779@naver.com
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Yong In, MD, PhD
Organizational Affiliation
the Catholic Univerisity of Korea Seoul St Mary's hospital
Official's Role
Study Chair
12. IPD Sharing Statement
Citations:
PubMed Identifier
28215966
Citation
Koh HJ, Koh IJ, Kim MS, Choi KY, Jo HU, In Y. Does Patient Perception Differ Following Adductor Canal Block and Femoral Nerve Block in Total Knee Arthroplasty? A Simultaneous Bilateral Randomized Study. J Arthroplasty. 2017 Jun;32(6):1856-1861. doi: 10.1016/j.arth.2017.01.025. Epub 2017 Jan 26.
Results Reference
derived
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Effectiveness of Pain Relief Between Adductor Canal Block and Femoral Nerve Block in Total Knee Arthroplasty
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