Effects of a Physiotherapist-delivered Dietary Weight Loss Program in People With Knee OA Who Have Overweight/Obesity
Knee Osteoarthritis, Overweight and Obesity
About this trial
This is an interventional treatment trial for Knee Osteoarthritis
Eligibility Criteria
Inclusion Criteria:
- Meet the National Institute for Health and Care Excellence [47] clinical criteria for OA: age≥45 years; activity-related knee joint pain; morning knee stiffness ≤ 30 mins
- report history of knee pain ≥ 3 months
- report knee pain on most days of the past month
- report a minimum knee pain score of 4 on an 11-point numeric rating scale during walking over the previous week
- body mass index (BMI) >27 kg/m2
- those using hypertensive medication must be willing to have their blood pressure checked (this can be self-monitoring, at a pharmacist or at a GP) if they feel light-headed or dizzy at any point during the study
- able to give informed consent and to participate fully in the interventions and assessment procedures
Exclusion Criteria:
- weight >150 kgs (due to the added complexities of additional nutritional requirements for individuals above this weight)
- inability to speak English
- on waiting list for/planning knee/hip surgery or bariatric surgery in next 6 months
- arthroplasty on affected knee
- recent knee surgery on affected knee (past 6 months);
- self-reported inflammatory arthritis (e.g. rheumatoid arthritis)
- weight loss of > 2 kg over the previous 3 months
- already actively trying to lose weight by any of the following mechanisms:using meal replacements for weight loss; being a member of a slimming club (e.g. weight watchers); receiving support from another health care professional for weight loss; using any drugs prescribed to aid in weight loss; using structured meal programs for weight loss such as 'Lite n' Easy'
- unwilling to continue current dietary patterns if randomized to exercise only group
- unable to undertake ketogenic VLCD for medical reasons including self-reported: diagnosis of Type 1 diabetes;Type 2 diabetes requiring insulin or other medication apart from metformin; Warfarin use; stroke or cardiac event in previous 6 months; unstable cardiovascular conditions; fluid intake restrictions; renal (kidney) problems (unless clearance is obtained from a general practitioner (GP), including GP confirmation that estimated glomerular filtration rate >30 mL/min/1.73m2); any neurological condition affecting lower limbs; vegan dietary requirements due to complexity of delivering a nutritionally complete diet within the ketogenic diet regime
Sites / Locations
- University of Melbourne
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Diet plus exercise
Exercise
The initial physiotherapy consultation for participants in this group will last 75 minutes, with 30 minutes for the exercise component and 45 minutes for the diet component. Thereafter, consultations will last 50 minutes, with 20 minutes for the exercise component and 30 minutes for the diet component. The exercise component will be the same as that described for the exercise alone group.
Physiotherapy consultations for participants in this group will last 30 minutes initially and then 20 minutes thereafter, consistent with clinical practice. Physiotherapists will prescribe 5-6 strengthening exercises from a pre-determined list to be performed at home three times/week, including two quadriceps exercises, one each for hip abductors, hamstrings and calf, and any other as appropriate and a personalised physical activity plan.