Effects of Dietary Amino Acids on Serum and Macrophage Atherogenicity
Atherosclerosis, Diet Modification, Serum; Disease
About this trial
This is an interventional other trial for Atherosclerosis focused on measuring Amino acids, Macrophage atherogenicity, Triglycerides, Cholesterol, Lipoproteins
Eligibility Criteria
Inclusion Criteria:
- healthy adult males between the ages of 18-50 after signing informed consent
Exclusion Criteria:
- pregnancy, renal, pulmonary, cardiovascular or endocrinal diseases, diabetes, cancer, morbid obesity (body mass index, BMI > 40 kg/m2), heavy smoking (> 20 cigarettes/day), or consumption of more than two alcoholic drinks per day. Subjects from the same hospital unit or from the laboratory where this study is conducted are also excluded
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm 7
Arm 8
Arm 9
Arm 10
Arm 11
Sham Comparator
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Control
Glycine (Trade name: Glycine)
Alanine (Trade name: L-Alanine)
Leucine (Trade name: L-Leucine)
Isoleucine (Trade name: L-Isoleucine)
Valine (Trade name: L-Valine)
Cysteine (Trade name: L-Cysteine)
Arginine (Trade name: L-Arginine)
Methionine (Trade name: DL-Methionine)
Glutamate (Trade name: L-Glutamic acid)
Glutamine (Trade name: L-Glutamine)
Other: Cellulose (control): cellulose, water soluble powder, 2 g in one daily dose, during 30 days
Dietary Supplement: Glycine, water soluble powder, 7.8 g daily in one dose, during 30 days.
Dietary Supplement: Alanine, water soluble powder, 8.5 g daily in one dose, during 30 days.
Dietary Supplement: Leucine, water soluble powder, 14 g daily in one dose, during 30 days.
Dietary Supplement: Isoleucine, water soluble powder, 8.2 g daily in one dose, during 30 days.
Dietary Supplement: Valine, water soluble powder, 9 g daily in one dose, during 30 days.
Dietary Supplement: Cysteine, water soluble powder, 2.2 g daily in one dose, during 30 days.
Dietary Supplement: Arginine, water soluble powder, 10 g daily in one dose, during 30 days.
Dietary Supplement: Methionine, water soluble powder, 4 g daily in one dose, during 30 days.
Dietary Supplement: Glutamate, water soluble powder, 33 g daily in one dose, during 30 days.
Dietary Supplement: Glutamine, water soluble powder, 30 g daily in one dose, during 30 days.