Back to resultsEffects of Inspiratory Muscle Training on Breathing Pattern in Patients With Chronic Obstructive Pulmonary Disease
Primary Purpose
Chronic Obstructive Pulmonary Disease, Muscle Weakness Conditions
Status
Completed
Phase
Not Applicable
Locations
Belgium
Study Type
Interventional
Intervention
Inspiratory muscle training
Sponsored by
About this trial
This is an interventional treatment trial for Chronic Obstructive Pulmonary Disease
Eligibility Criteria
Inclusion Criteria:
- Clinically stable COPD patients
- maximal inspiratory pressure <100% of the predicted normal value
Exclusion Criteria:
- Major comorbidities preventing successful participation in an 8 week exercise training intervention
Sites / Locations
- University Hospital Leuven
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Inspiratory muscle training
Arm Description
Outcomes
Primary Outcome Measures
Change in breathing pattern during an incremental cycle exercise test
At comparable levels of ventilation breathing frequency, inspiratory time (Ti), expiratory time (Te), total time of the respiratory cycle (Ttot), inspiratory duty cycle (Ti/Ttot), and inspiratory flow rates will be compared.
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT02186340
Brief Title
Effects of Inspiratory Muscle Training on Breathing Pattern in Patients With Chronic Obstructive Pulmonary Disease
Study Type
Interventional
2. Study Status
Record Verification Date
August 2015
Overall Recruitment Status
Completed
Study Start Date
January 2013 (undefined)
Primary Completion Date
July 2015 (Actual)
Study Completion Date
July 2015 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
KU Leuven
4. Oversight
5. Study Description
Brief Summary
The improvement in inspiratory muscle function might result in beneficial changes in breathing pattern during whole body exercise. The hypothesis is the effect of inspiratory muscle training as an adjunct to a pulmonary rehabilitation program improves the breathing pattern during an incremental cycle exercise.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Chronic Obstructive Pulmonary Disease, Muscle Weakness Conditions
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
Outcomes Assessor
Allocation
N/A
Enrollment
50 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Inspiratory muscle training
Arm Type
Experimental
Intervention Type
Procedure
Intervention Name(s)
Inspiratory muscle training
Primary Outcome Measure Information:
Title
Change in breathing pattern during an incremental cycle exercise test
Description
At comparable levels of ventilation breathing frequency, inspiratory time (Ti), expiratory time (Te), total time of the respiratory cycle (Ttot), inspiratory duty cycle (Ti/Ttot), and inspiratory flow rates will be compared.
Time Frame
Baseline and 8 weeks follow-up
10. Eligibility
Sex
All
Minimum Age & Unit of Time
40 Years
Maximum Age & Unit of Time
90 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Clinically stable COPD patients
maximal inspiratory pressure <100% of the predicted normal value
Exclusion Criteria:
Major comorbidities preventing successful participation in an 8 week exercise training intervention
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Rik PT Gosselink, PhD
Organizational Affiliation
KU Leuven
Official's Role
Principal Investigator
Facility Information:
Facility Name
University Hospital Leuven
City
Leuven
ZIP/Postal Code
3000
Country
Belgium
12. IPD Sharing Statement
Citations:
PubMed Identifier
26917617
Citation
Charususin N, Gosselink R, McConnell A, Demeyer H, Topalovic M, Decramer M, Langer D. Inspiratory muscle training improves breathing pattern during exercise in COPD patients. Eur Respir J. 2016 Apr;47(4):1261-4. doi: 10.1183/13993003.01574-2015. Epub 2016 Feb 25. No abstract available.
Results Reference
derived
Learn more about this trial
Effects of Inspiratory Muscle Training on Breathing Pattern in Patients With Chronic Obstructive Pulmonary Disease
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