search
Back to results

Effects of Neuromobilization on Median Nerve Elasticity

Primary Purpose

Median Nerve Disease

Status
Completed
Phase
Not Applicable
Locations
Turkey
Study Type
Interventional
Intervention
neuromobilization exercises
Sponsored by
Istinye University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Median Nerve Disease focused on measuring neuromobilization, elasticity, shear wave elastography

Eligibility Criteria

18 Years - 30 Years (Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • 18-30 years of age
  • Healthy individuals without any known systemic disease

Exclusion Criteria:

  • Those who have undergone an upper extremity bone-tendon-muscle operation in the last six months
  • People with a systemic disease such as rheumatoid arthritis, diabetes mellitus
  • Patients with any neuromuscular disease

Sites / Locations

  • İstinye University

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm Type

Experimental

Experimental

No Intervention

Arm Label

neuromobilization stretching group

neuromobilization shifting group

Control Group

Arm Description

In the neuromobilization stretching group; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, median nerve stretching was performed by extending the participant's head to the opposite side while flexing the wrist and finger. After waiting for 30 seconds in this position, the wrist and head were moved to the neutral position and the participants relaxed.

In the neuromobilization shifting group, the subjects were brought to shoulder depression and 90 degrees of abduction while the dominant forearms were supination. In this position, the participant flexed his wrist and fingers while lateral flexion of his head to the opposite side, and flexed his wrist and fingers while lateral flexion of the head to the same side. Thus, the participants performed median nerve shift.

The dominant sides of the individuals are experimental sides and the other nondominant sides of the participants are control sides. And no intervention was made. All measurements were done bilaterally before and after.

Outcomes

Primary Outcome Measures

Median Nerve Tension Test
The test was performed in a position with shoulder depression and 90 degrees abduction and external rotation, elbow 90 degrees flexion, forearm full supination, and wrist and fingers fully extended. Maintaining this position, the elbow was passively extended and the tension of the median nerve was tested. The test was stopped at the point where the patient felt pain and tension, and the angle at the elbow was measured by a universal goniometer.
Median nerve elasticity with Shear Wave Ultrasound Elastography
The nerve elasticity was measured by measuring the velocity of shear waves in the median nerve by means of high frequency ultrasound waves.
Bilaterally finger grip strength with pinchmeter
finger grip strength was measured bilaterally by pinch meter.

Secondary Outcome Measures

Full Information

First Posted
January 2, 2020
Last Updated
July 28, 2020
Sponsor
Istinye University
search

1. Study Identification

Unique Protocol Identification Number
NCT04218175
Brief Title
Effects of Neuromobilization on Median Nerve Elasticity
Official Title
Effects of Neuromobilization on Median Nerve Elasticity
Study Type
Interventional

2. Study Status

Record Verification Date
July 2020
Overall Recruitment Status
Completed
Study Start Date
November 10, 2019 (Actual)
Primary Completion Date
December 15, 2019 (Actual)
Study Completion Date
December 25, 2019 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Istinye University

4. Oversight

Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No

5. Study Description

Brief Summary
Purpose: The aim of this study was to investigate the effect of median nerve neuromobilization on median nerve elasticity using shear wave elastography. Methods: The study included 36 healthy volunteers (72 upper extremities) aged 18-30 years. Inclusion criteria; no known systemic neuromuscular and metabolic diseases, no nerve impingement syndrome, and no upper extremity bone-tendon-muscle surgery in the last six months. Sociodemographic data of the participants were recorded. Wrist flexion and extension bilaterally with universal goniometer and finger grip strength bilaterally were measured with pinchmeter. Median Nerve Stress Test was performed. Median nerve elasticity was measured by Shear Wave Ultrasound Elastography. The extremity of the dominant side as a study group and the non-dominant side as a control group were measured bilaterally. Median nerve neuromobilization (stretching (n = 18) and shifting (n = 18)) was applied to the upper extremities of the dominant side. The application was carried out as 3 sets in one session. Evaluations were repeated after application.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Median Nerve Disease
Keywords
neuromobilization, elasticity, shear wave elastography

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Model Description
The researcher who performed shear wave elastography did not know which group the case was evaluated during the measurement.
Masking
Outcomes Assessor
Allocation
Randomized
Enrollment
18 (Actual)

8. Arms, Groups, and Interventions

Arm Title
neuromobilization stretching group
Arm Type
Experimental
Arm Description
In the neuromobilization stretching group; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, median nerve stretching was performed by extending the participant's head to the opposite side while flexing the wrist and finger. After waiting for 30 seconds in this position, the wrist and head were moved to the neutral position and the participants relaxed.
Arm Title
neuromobilization shifting group
Arm Type
Experimental
Arm Description
In the neuromobilization shifting group, the subjects were brought to shoulder depression and 90 degrees of abduction while the dominant forearms were supination. In this position, the participant flexed his wrist and fingers while lateral flexion of his head to the opposite side, and flexed his wrist and fingers while lateral flexion of the head to the same side. Thus, the participants performed median nerve shift.
Arm Title
Control Group
Arm Type
No Intervention
Arm Description
The dominant sides of the individuals are experimental sides and the other nondominant sides of the participants are control sides. And no intervention was made. All measurements were done bilaterally before and after.
Intervention Type
Other
Intervention Name(s)
neuromobilization exercises
Intervention Description
Median nerve neuromobilization (stretching and shifting) was performed. For median nerve stretching; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, median nerve stretching was performed by extending the participant's head to the opposite side while flexing the wrist and finger. After waiting for 30 seconds in this position, the wrist and head were moved to the neutral position and the participants relaxed. For median nerve shift; The subjects were brought to shoulder depression and 90 degrees of abduction while the dominant side forearms were supination. In this position, the participant flexed his wrist and fingers while lateral flexion of his head to the opposite side, and flexed his wrist and fingers while lateral flexion of the head to the same side.
Primary Outcome Measure Information:
Title
Median Nerve Tension Test
Description
The test was performed in a position with shoulder depression and 90 degrees abduction and external rotation, elbow 90 degrees flexion, forearm full supination, and wrist and fingers fully extended. Maintaining this position, the elbow was passively extended and the tension of the median nerve was tested. The test was stopped at the point where the patient felt pain and tension, and the angle at the elbow was measured by a universal goniometer.
Time Frame
4 weeks
Title
Median nerve elasticity with Shear Wave Ultrasound Elastography
Description
The nerve elasticity was measured by measuring the velocity of shear waves in the median nerve by means of high frequency ultrasound waves.
Time Frame
4 weeks
Title
Bilaterally finger grip strength with pinchmeter
Description
finger grip strength was measured bilaterally by pinch meter.
Time Frame
4 weeks

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
30 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: 18-30 years of age Healthy individuals without any known systemic disease Exclusion Criteria: Those who have undergone an upper extremity bone-tendon-muscle operation in the last six months People with a systemic disease such as rheumatoid arthritis, diabetes mellitus Patients with any neuromuscular disease
Facility Information:
Facility Name
İstinye University
City
Istanbul
ZIP/Postal Code
34010
Country
Turkey

12. IPD Sharing Statement

Learn more about this trial

Effects of Neuromobilization on Median Nerve Elasticity

We'll reach out to this number within 24 hrs