Effects of Vitamin B1 in Type 1 Diabetic Patients
Diabetes Mellitus, Type 1
About this trial
This is an interventional treatment trial for Diabetes Mellitus, Type 1 focused on measuring Diabetes Complications, benfotiamine, type 1 diabetes, elevated urinary albumin excretion, nerve function, advanced glycation end products
Eligibility Criteria
Inclusion Criteria: Type 1 diabetes (of at least 15 years duration) as assessed by medical history. Exclusion Criteria: Macroalbuminuria Symptomatic gastroparesis. Diabetic nephropathy with a creatinine clearance less than 60 cc/min. Evidence of chronic infection. History of any malignancy. Any chronic medical condition that unduly increases the risk for the potential enrollee as judged by study investigators. Pregnancy, breastfeeding or planned pregnancy within two years. Supplementation with thiamine > 2mg per day and/or alpha-lipoic acid Chronic alcoholism/alcohol abuse.
Sites / Locations
- Aker University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Benfotiamine
Placebo
Benfotiamine 300mg/day
Placebo for benfotiamine