Effects of Vitamin D on Cardiovascular Health in Black Women
Vitamin d Deficiency
About this trial
This is an interventional prevention trial for Vitamin d Deficiency focused on measuring vitamin D, black women, blood pressure, sleep, vascular
Eligibility Criteria
Inclusion Criteria: Female Self-identified race is Black 18-30 years old Serum 25-hydroxyvitamin D concentration between 8-29.9 ng/ml determined at screening visit Exclusion Criteria: Unwilling or unable to give consent Unwilling or unable to undergo a venous blood draw Diagnosed with any chronic diseases or conditions including cardiometabolic diseases, cardiorespiratory diseases, chronic mental or psychological illness, musculoskeletal diseases/conditions, autoimmune diseases, cancer, gastrointestinal/malabsorption disorders, hyper-/hypocalcemia, hyper-/hypoparathyroidism, hyper-/hypothyroidism, kidney disease, or a history of kidney stones Taking medication that may influence blood pressure or blood vessel function Diagnosed with a sleep disorder (e.g., insomnia, restless leg syndrome, sleep apnea), or are at high risk for a sleep disorder according to the ISI (score >14) or STOP-bang (score ≥3) questionnaires Currently taking medications or supplements that affect sleep (e.g., Ambien, sedatives, melatonin, etc.) Currently working night-shift work Resting blood pressure >130 or >80 mmHg BMI >30 kg/m2 Currently pregnant, breast feeding, peri-menopausal, or post-menopausal Currently use tobacco (≥1 cigarette in the last month) Had COVID-19 in the past 60 days Received the COVID-19 vaccine or booster within in the past 14 days
Sites / Locations
- University of DelawareRecruiting
Arms of the Study
Arm 1
Experimental
Vitamin D
5,000 IU of oral vitamin D3 in white powder form, daily for 8 continuous weeks