Efficacy of a High-intensity Physical Activity Program on Renal Function in High Risk Patients With Type 2 Diabetes (ACTIDIANE)
Type2 Diabetes, Diabetic Kidney Disease
About this trial
This is an interventional treatment trial for Type2 Diabetes focused on measuring High-intensity physical activity, Diabetes, Renal function decline
Eligibility Criteria
Inclusion Criteria:
- Type 2 diabetes
- Rapid renal decline function (yearly loss of eGFR over -5ml/min/1.73 m2) in the 6 to 24 preceding months
Exclusion Criteria:
- Lower limb amputation
- Indication for rehabilitation program
- Contra-indication for physical activity
- Unstable angina, left atrial thrombus,
- Unstable thyroid function
- Corticosteroids treatment
- Long-term NSAIDs
- Simultaneous participation to any interventional study able to interfere with the current study endpoints
Sites / Locations
- Hospital of LiègeRecruiting
- Besançon HospitalRecruiting
- Bordeaux University HospitalRecruiting
- Caen University HospitalRecruiting
- CH ChartresRecruiting
- Clermont Ferrand University HospitalRecruiting
- CHG Sud FrancilienRecruiting
- CHU DijonRecruiting
- CHU LilleRecruiting
- Chu de LyonRecruiting
- CHRURecruiting
- CHU NancyRecruiting
- Chu de NiceRecruiting
- Bichat University HospitalRecruiting
- La Riboisière HospitalRecruiting
- Hôpital Pitié SalpétrièreRecruiting
- Poitiers University HospitalRecruiting
- CHU StrasbourgRecruiting
- CHU ToulouseRecruiting
- CHU de TOURSRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
HIPA group
Control group
Twice weekly physical activity session in a dedicated structure, supervised by a graduated coach, alternating sessions of strengthening and intermittent HIPA, allowing a mixed stimulation of neuro-muscular and cardiovascular systems, and regular (every 3 months) adjustment of the intensity of the program. The sessions will be preferably performed in sports gyms but if required can also be performed online with supervised coaches, trained for the study.
Counseling of physical activity according to recommendations from the working group on Physical Activity of the SFD (French Language Diabetes Society).