Efficacy of the 6-point Diet (PIS)
Chronic Kidney Disease
About this trial
This is an interventional treatment trial for Chronic Kidney Disease focused on measuring Chronic kidney disease, Low protein diet, CKD stage 3b-5
Eligibility Criteria
Inclusion Criteria:
- age >18 years
- a basal value of estimated GFR (eGFR) < 45 ml/min/1,73 m2, that had to remain stable during 3 consecutive controls (eGFR variability <15% along 1 month)
Exclusion Criteria:
- unstable renal function,
- inability to perform correct 24-hours urine collections,
- presence of malignancies,
- treatment with immunosuppressive drugs,
- pregnancy,
- congestive heart failure (NYHA class III-IV),
- proteinuria >3,5 g/24 hours
Sites / Locations
- federico II university, department of nephrology
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Low protein diet
Six point diet
The patients of this group received a classical low protein diet (LPD),according to their desired body weight (DBW), obtained by multiplying the squared value of the height times a reference body mass index (BMI) value of 23. LPD were individually prepared and explained to the patients by a dedicated dietician and contained at least 30 kcal/kg/day (25 in overweight patients), with a dietary sodium intake restricted to 2.5 g/day.
These patients were assigned to receive the 6-points-diet, and were given by the Nephrologist the list of six items indicating how to modify their dietary habits; all the items were thoroughly explained and discussed with the patients