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Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

Primary Purpose

Irritable Bowel Syndrome

Status

Completed

Phase

Phase 3

Locations

International

Study Type

Interventional

Intervention

Eluxadoline

Placebo

About this trial

This is an interventional treatment trial for Irritable Bowel Syndrome

Eligibility Criteria

18 Years - 80 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

Participant has a diagnosis of irritable bowel syndrome (IBS) with a subtype of diarrhea defined by the Rome III criteria.
Participant has had a colonoscopy performed:
- Within 10 years prior to Prescreening if participant is at least 50 years of age (sigmoidoscopy, double contrast barium enema, or computed tomography (CT) colonography within the past 5 years is acceptable)
- Since the onset (if applicable) of any of the following alarm features for participants of any age:
  - Participant has documented weight loss within the past 6 months
  - Participant has nocturnal symptoms
  - Participant has a familial history of first-degree relatives with colon cancer or
  - Participant has blood mixed with their stool (excluding blood from hemorrhoids).
Female participants must be:
- Postmenopausal, defined as 52 years or older and amenorrheic for at least 2 years at Prescreening,
- Surgically sterile (have had a hysterectomy or bilateral oophorectomy, tubal ligation, or otherwise be incapable of pregnancy),
- Abstinent, or
- If sexually active, be practicing an effective method of birth control.

Exclusion Criteria:

Participant has a diagnosis of IBS with a subtype of constipation, mixed IBS, or unsubtyped IBS by the Rome III criteria.
Participant has a history of inflammatory or immune-mediated gastrointestinal (GI) disorders including inflammatory bowel disease (ie, Crohn's disease, ulcerative colitis) and celiac disease.
Participant has a history of diverticulitis within 3 months prior to Prescreening.
Participant has a history of intestinal obstruction, stricture, toxic megacolon, GI perforation, fecal impaction, gastric banding, bariatric surgery, adhesions, ischemic colitis, or impaired intestinal circulation (eg, aortoiliac disease).
Participant has any of the following surgical history:
- Cholecystectomy with any history of post cholecystectomy biliary tract pain
- Any abdominal surgery within the 3 months prior to Prescreening
- Participant has a history of major gastric, hepatic, pancreatic, or intestinal surgery (appendectomy, hemorrhoidectomy, or polypectomy greater than 3 months post surgery are allowed)

Other protocol-specific eligibility criteria may apply.

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm Type

Experimental

Placebo Comparator

Arm Label

Eluxadoline 75 mg

Eluxadoline 100 mg

Placebo

Arm Description

Eluxadoline 75 mg tablets, orally, twice daily for up to 52 weeks period.

Eluxadoline 100 mg tablets, orally, twice daily for up to 52 weeks period.

Eluxadoline placebo matching tablets, orally, twice daily for up to 52 weeks period.

Outcomes

Primary Outcome Measures

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain And Daily Stool Consistency Scores

Composite responders were defined as a participant who met the daily response criteria for at least 50% of the days with diary entries during the interval of interest. A participant must had met both of the following criteria on a given day to be a daily responder: 1) Daily pain response: worst abdominal pain scores in the past 24 hours improved by ≥30% compared to baseline (average of daily worst abdominal pain the week prior to randomization). 2) Daily stool consistency response: Bristol Stool Scale (BSS) score <5 (ie, score of 1, 2, 3, or 4) or the absence of a bowel movement if accompanied by ≥30% improvement in worst abdominal pain compared to baseline pain. Bristol stool scale was defined as 7-point Scale in which a score of 1 = separate hard lumps, 2 = sausage shaped but lumpy, 3 = sausage-like with cracks on the surface, 4 = sausage-like but smooth and soft, 5 = soft blobs with clear cut edges, 6 = fluffy pieces with ragged edges, and 7 = watery with no solid pieces.

Secondary Outcome Measures

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain And Daily Stool Consistency Scores

Percentage of Participants Who Were Pain Responders In Daily Worst Abdominal Pain Scores by Intervals

Pain responders were defined as participants who met the daily pain response criteria (ie, the worst abdominal pain score in the past 24 hours improved by ≥30% compared to baseline) for at least 50% of days with diary entries during each interval. A participant must have had a minimum of 20 days of diary entries over any 4-week interval, a minimum of 60 days of diary entries over the 12-week interval, and a minimum of 110 days of diary entries over the 26-week interval to be a responder.

Percentage of Participants Who Were Responders In Daily Stool Consistency Scores by Intervals

Stool consistency responders: participants who met daily stool consistency response criterion (ie,score of 1, 2, 3, or 4 or absence of bowel movement if accompanied by ≥30% improvement in worst abdominal pain compared to baseline pain) for at least 50% of days with diary entries during each interval. BSS was defined as 7-point Scale in which score of 1= separate hard lumps, 2= sausage shaped but lumpy, 3= sausage-like with cracks on the surface, 4= sausage-like but smooth and soft, 5= soft blobs with clear cut edges, 6= fluffy pieces with ragged edges, and 7= watery with no solid pieces. A participant must have had a minimum of 20 days of diary entries over any 4-week interval, a minimum of 60 days of diary entries over 12-week interval, and a minimum of 110 days of diary entries over 26-week interval to be a responder.

Percentage of Participants Who Were Responders In Irritable Bowel Syndrome, Diarrhea Predominant (IBS-d) Global Symptom Scale by Intervals

IBS-d global symptom responders were defined as those participants who met the daily IBS-d global symptom response criteria (ie, IBS-d global symptom score of 0 [none] or 1 [mild]; or a daily IBS-d global symptom score improved by ≥2.0 compared to the baseline average) for at least 50% of days with diary entries during each interval. IBS-d Global Symptom Scale was a 5 point scale, score ranging from 0 to 4. 0= no symptoms, 1= mild symptoms, 2= moderate symptoms, 3= severe symptoms and 4 = very severe symptoms. A participant must have had a minimum of 20 days of diary entries over any 4-week interval, a minimum of 60 days of diary entries over the 12-week interval, and a minimum of 110 days of diary entries over the 26-week interval to be a responder.

Percentage of Participants Who Were Responders to the Irritable Bowel Syndrome Quality of Life Measure (IBS-QoL) Scale

IBS-QoL responders were defined as participants who achieved at least a 14-point improvement in IBS-QoL total score from baseline to the applicable visit. The IBS-QoL consists of 34 items each with a 5-point response scale, where 1 generally represents better responses on items and 5 represents worse responses. The individual responses to the answered items were summed and standardized for a total score and then transformed to a 0- to 100-point (0= worst; 100=better) scale for ease of interpretation.

Percentage of Participants With Irritable Bowel Syndrome - Adequate Relief (IBS-AR) Scale

Adequate relief of IBS symptoms was assessed once weekly by participants answering the IBS-AR item in the electronic diary. IBS-AR responders were defined as participants with a weekly response of "Yes" to adequate relief of their IBS symptoms for at least 50% of the total weeks during the interval. A participant must have had a positive response on ≥6 weeks for the 12-week interval and ≥13 weeks for the 26-week interval, regardless of diary compliance, to be a responder.

Change From Baseline in Daily Abdominal Discomfort Scores

Symptoms of abdominal discomfort were recorded on a 0 to 10 scale, where 0 corresponded to no discomfort and 10 corresponded to worst imaginable discomfort. A negative change from Baseline indicates the discomfort decreased.

Change From Baseline in Daily Abdominal Bloating Scores

Symptoms of abdominal bloating were recorded on a 0 to 10 scale, where 0 corresponded to no bloating and 10 corresponded to worst imaginable bloating. A negative change from Baseline indicates the bloating decreased.

Number of Bowel Movements Per Day

Participants recorded the number of bowel movements over 24 hours daily throughout the treatment.

Number of Bowel Incontinence Episodes

Participants recorded the number of incontinence episodes over 24 hours daily throughout the treatment.

Number of Bowel Incontinence Free Days

An incontinence free day was one where the participant reports zero incontinence episodes. The number of incontinence free days for a participant was assessed each week based on the number of reported days.

Number of Urgency Episodes Per Day

Participants recorded the number of urgency episodes over 24 hours daily throughout the treatment.

IBS-QoL Total Scores

The IBS-QoL consists of 34 items each with a 5-point response scale, where 1 generally represents better responses on items and 5 represents worse responses. The individual responses to the answered items were summed and standardized for a total score and then transformed to a 0- to 100- point scale (0=worst; 100=better) for ease of interpretation.

Change From Baseline in IBS-QoL Total Scores

Full Information

NCT ID

NCT01553591

First Posted

March 8, 2012

Last Updated

August 3, 2018

Sponsor

Furiex Pharmaceuticals, Inc

1. Study Identification

Unique Protocol Identification Number

NCT01553591

Brief Title

Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

Official Title

A Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-27018966 in the Treatment of Patients With Diarrhea-Predominant Irritable Bowel Syndrome

Study Type

Interventional

2. Study Status

Record Verification Date

August 2018

Overall Recruitment Status

Completed

Study Start Date

May 29, 2012 (Actual)

Primary Completion Date

July 29, 2014 (Actual)

Study Completion Date

July 29, 2014 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Furiex Pharmaceuticals, Inc

4. Oversight

Data Monitoring Committee

5. Study Description

Brief Summary

The purpose of this study is to determine the efficacy, safety, and tolerability of different doses of eluxadoline (JNJ-27018966) compared with placebo in the treatment of participants with diarrhea-predominant irritable bowel syndrome.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Irritable Bowel Syndrome

7. Study Design

Primary Purpose

Treatment

Study Phase

Phase 3

Interventional Study Model

Parallel Assignment

Masking

ParticipantCare ProviderInvestigator

Allocation

Randomized

Enrollment

1282 (Actual)

8. Arms, Groups, and Interventions

Arm Title

Eluxadoline 75 mg

Arm Type

Experimental

Arm Description

Eluxadoline 75 mg tablets, orally, twice daily for up to 52 weeks period.

Arm Title

Eluxadoline 100 mg

Arm Type

Experimental

Arm Description

Eluxadoline 100 mg tablets, orally, twice daily for up to 52 weeks period.

Arm Title

Placebo

Arm Type

Placebo Comparator

Arm Description

Eluxadoline placebo matching tablets, orally, twice daily for up to 52 weeks period.

Intervention Type

Drug

Intervention Name(s)

Eluxadoline

Other Intervention Name(s)

JNJ-27018966

Intervention Description

Oral tablets twice daily

Intervention Type

Drug

Intervention Name(s)

Placebo

Intervention Description

Oral tablets twice daily

Primary Outcome Measure Information:

Title

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain And Daily Stool Consistency Scores

Description

Time Frame

Up to 12 Weeks

Secondary Outcome Measure Information:

Title

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain And Daily Stool Consistency Scores

Description

Time Frame

Up to 26 Weeks

Title

Percentage of Participants Who Were Pain Responders In Daily Worst Abdominal Pain Scores by Intervals

Description

Time Frame

12-week interval (Weeks 1-12), 26-week interval (Weeks 1-26), and 4-week interval (Weeks 1-4, 5-8, 9-12, 13-16, 17-20, and 21-24)

Title

Percentage of Participants Who Were Responders In Daily Stool Consistency Scores by Intervals

Description

Time Frame

12-week interval (Weeks 1-12), 26-week interval (Weeks 1-26), and 4-week interval (Weeks 1-4, 5-8, 9-12, 13-16, 17-20, and 21-24)

Title

Percentage of Participants Who Were Responders In Irritable Bowel Syndrome, Diarrhea Predominant (IBS-d) Global Symptom Scale by Intervals

Description

Time Frame

12-week interval (Weeks 1-12), 26-week interval (Weeks 1-26), and 4-week interval (Weeks 1-4, 5-8, 9-12, 13-16, 17-20, and 21-24)

Title

Percentage of Participants Who Were Responders to the Irritable Bowel Syndrome Quality of Life Measure (IBS-QoL) Scale

Description

Time Frame

Weeks 4, 8, 12, 18, 26, 36, 44, and 52 (End of Treatment [EOT])

Title

Percentage of Participants With Irritable Bowel Syndrome - Adequate Relief (IBS-AR) Scale

Description

Time Frame

12-week interval (Weeks 1-12) and 26-week interval (Weeks 1-26)

Title

Change From Baseline in Daily Abdominal Discomfort Scores

Description

Time Frame

Baseline, Weeks 4, 12 and 26

Title

Change From Baseline in Daily Abdominal Bloating Scores

Description

Time Frame

Baseline, Weeks 4, 12 and 26

Title

Number of Bowel Movements Per Day

Description

Participants recorded the number of bowel movements over 24 hours daily throughout the treatment.

Time Frame

Weeks 4, 12 and 26

Title

Number of Bowel Incontinence Episodes

Description

Participants recorded the number of incontinence episodes over 24 hours daily throughout the treatment.

Time Frame

Weeks 4, 12 and 26

Title

Number of Bowel Incontinence Free Days

Description

Time Frame

Weeks 4, 12 and 26

Title

Number of Urgency Episodes Per Day

Description

Participants recorded the number of urgency episodes over 24 hours daily throughout the treatment.

Time Frame

Weeks 4, 12 and 26

Title

IBS-QoL Total Scores

Description

Time Frame

Weeks 4, 8, 12, 18, 26, 36, 44, and 52 (EOT)

Title

Change From Baseline in IBS-QoL Total Scores

Description

Time Frame

Baseline, Weeks 4, 8, 12, 18, 26, 36, 44, and 52/EOT

10. Eligibility

Sex

All

Minimum Age & Unit of Time

18 Years

Maximum Age & Unit of Time

80 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Participant has a diagnosis of irritable bowel syndrome (IBS) with a subtype of diarrhea defined by the Rome III criteria. Participant has had a colonoscopy performed: Within 10 years prior to Prescreening if participant is at least 50 years of age (sigmoidoscopy, double contrast barium enema, or computed tomography (CT) colonography within the past 5 years is acceptable) Since the onset (if applicable) of any of the following alarm features for participants of any age: Participant has documented weight loss within the past 6 months Participant has nocturnal symptoms Participant has a familial history of first-degree relatives with colon cancer or Participant has blood mixed with their stool (excluding blood from hemorrhoids). Female participants must be: Postmenopausal, defined as 52 years or older and amenorrheic for at least 2 years at Prescreening, Surgically sterile (have had a hysterectomy or bilateral oophorectomy, tubal ligation, or otherwise be incapable of pregnancy), Abstinent, or If sexually active, be practicing an effective method of birth control. Exclusion Criteria: Participant has a diagnosis of IBS with a subtype of constipation, mixed IBS, or unsubtyped IBS by the Rome III criteria. Participant has a history of inflammatory or immune-mediated gastrointestinal (GI) disorders including inflammatory bowel disease (ie, Crohn's disease, ulcerative colitis) and celiac disease. Participant has a history of diverticulitis within 3 months prior to Prescreening. Participant has a history of intestinal obstruction, stricture, toxic megacolon, GI perforation, fecal impaction, gastric banding, bariatric surgery, adhesions, ischemic colitis, or impaired intestinal circulation (eg, aortoiliac disease). Participant has any of the following surgical history: Cholecystectomy with any history of post cholecystectomy biliary tract pain Any abdominal surgery within the 3 months prior to Prescreening Participant has a history of major gastric, hepatic, pancreatic, or intestinal surgery (appendectomy, hemorrhoidectomy, or polypectomy greater than 3 months post surgery are allowed) Other protocol-specific eligibility criteria may apply.

Facility Information:

Facility Name

Furiex Research Site

City

Athens

State/Province

Alabama

ZIP/Postal Code

35611

Country

United States

Facility Name

Furiex Research Site

City

Birmingham

State/Province

Alabama

ZIP/Postal Code

35213

Country

United States

Facility Name

Furiex Research Site

City

Foley

State/Province

Alabama

ZIP/Postal Code

36535

Country

United States

Facility Name

Furiex Research Site

City

Huntsville

State/Province

Alabama

ZIP/Postal Code

35802

Country

United States

Facility Name

Furiex Research Site

City

Ozark

State/Province

Alabama

ZIP/Postal Code

36360

Country

United States

Facility Name

Furiex Research Site

City

Chandler

State/Province

Arizona

ZIP/Postal Code

85224

Country

United States

Facility Name

Furiex Research Site

City

Glendale

State/Province

Arizona

ZIP/Postal Code

85306

Country

United States

Facility Name

Furiex Research Site

City

Mesa

State/Province

Arizona

ZIP/Postal Code

85213

Country

United States

Facility Name

Furiex Research Site

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85018

Country

United States

Facility Name

Furiex Research Site

City

Tucson

State/Province

Arizona

ZIP/Postal Code

85712

Country

United States

Facility Name

Furiex Research Site

City

Little Rock

State/Province

Arkansas

ZIP/Postal Code

72211

Country

United States

Facility Name

Furiex Research Site

City

Little Rock

State/Province

Arkansas

ZIP/Postal Code

72212

Country

United States

Facility Name

Furiex Research Site

City

North Little Rock

State/Province

Arkansas

ZIP/Postal Code

72117

Country

United States

Facility Name

Furiex Research Site

City

Azusa

State/Province

California

ZIP/Postal Code

91702

Country

United States

Facility Name

Furiex Research Site

City

Bell Gardens

State/Province

California

ZIP/Postal Code

90201

Country

United States

Facility Name

Furiex Research Site

City

Beverly Hills

State/Province

California

ZIP/Postal Code

90211

Country

United States

Facility Name

Furiex Research Site

City

Carson

State/Province

California

ZIP/Postal Code

91105

Country

United States

Facility Name

Furiex Research Site

City

Chula Vista

State/Province

California

ZIP/Postal Code

91910

Country

United States

Facility Name

Furiex Research Site

City

Corona

State/Province

California

ZIP/Postal Code

92880

Country

United States

Facility Name

Furiex Research Site

City

El Cajon

State/Province

California

ZIP/Postal Code

92020

Country

United States

Facility Name

Furiex Research Site

City

Encino

State/Province

California

ZIP/Postal Code

91436

Country

United States

Facility Name

Furiex Research Site

City

Garden Grove

State/Province

California

ZIP/Postal Code

92843

Country

United States

Facility Name

Furiex Research Site

City

Lomita

State/Province

California

ZIP/Postal Code

90717

Country

United States

Facility Name

Furiex Research Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90022

Country

United States

Facility Name

Furiex Research Site

City

Monterey Park

State/Province

California

ZIP/Postal Code

91754

Country

United States

Facility Name

Furiex Research Site

City

Murrieta

State/Province

California

ZIP/Postal Code

92562

Country

United States

Facility Name

Furiex Research Site

City

Newport Beach

State/Province

California

ZIP/Postal Code

92663

Country

United States

Facility Name

Furiex Research Site

City

North Hollywood

State/Province

California

ZIP/Postal Code

91606

Country

United States

Facility Name

Furiex Research Site

City

Oakland

State/Province

California

ZIP/Postal Code

94612

Country

United States

Facility Name

Furiex Research Site

City

Oxnard

State/Province

California

ZIP/Postal Code

93030

Country

United States

Facility Name

Furiex Research Site

City

Pismo Beach

State/Province

California

ZIP/Postal Code

93449

Country

United States

Facility Name

Furiex Research Site

City

Poway

State/Province

California

ZIP/Postal Code

92064

Country

United States

Facility Name

Furiex Research Site

City

Riverside

State/Province

California

ZIP/Postal Code

92501

Country

United States

Facility Name

Furiex Research Site

City

Roseville

State/Province

California

ZIP/Postal Code

95661

Country

United States

Facility Name

Furiex Research Site

City

Sacramento

State/Province

California

ZIP/Postal Code

95825

Country

United States

Facility Name

Furiex Research Site

City

San Diego

State/Province

California

ZIP/Postal Code

92103

Country

United States

Facility Name

Furiex Research Site

City

San Diego

State/Province

California

ZIP/Postal Code

92114

Country

United States

Facility Name

Furiex Research Site

City

Santa Monica

State/Province

California

ZIP/Postal Code

90404

Country

United States

Facility Name

Furiex Research Site

City

Thousand Oaks

State/Province

California

ZIP/Postal Code

91360

Country

United States

Facility Name

Furiex Research Site

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80904

Country

United States

Facility Name

Furiex Research Site

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80907

Country

United States

Facility Name

Furiex Research Site

City

Lafayette

State/Province

Colorado

ZIP/Postal Code

80026

Country

United States

Facility Name

Furiex Research Site

City

Lakewood

State/Province

Colorado

ZIP/Postal Code

80215

Country

United States

Facility Name

Furiex Research Site

City

Longmont

State/Province

Colorado

ZIP/Postal Code

80501

Country

United States

Facility Name

Furiex Research Site

City

Norwalk

State/Province

Connecticut

ZIP/Postal Code

06851

Country

United States

Facility Name

Furiex Research Site

City

Ridgefield

State/Province

Connecticut

ZIP/Postal Code

06877

Country

United States

Facility Name

Furiex Research Site

City

Boca Raton

State/Province

Florida

ZIP/Postal Code

33428

Country

United States

Facility Name

Furiex Research Site

City

Brandon

State/Province

Florida

ZIP/Postal Code

33511

Country

United States

Facility Name

Furiex Research Site

City

Clearwater

State/Province

Florida

ZIP/Postal Code

33765

Country

United States

Facility Name

Furiex Research Site

City

Cooper City

State/Province

Florida

ZIP/Postal Code

33024

Country

United States

Facility Name

Furiex Research Site

City

Coral Springs

State/Province

Florida

ZIP/Postal Code

33065

Country

United States

Facility Name

Furiex Research Site

City

Crystal River

State/Province

Florida

ZIP/Postal Code

34429

Country

United States

Facility Name

Furiex Research Site

City

Doral

State/Province

Florida

ZIP/Postal Code

33172

Country

United States

Facility Name

Furiex Research Site

City

Eustis

State/Province

Florida

ZIP/Postal Code

32726

Country

United States

Facility Name

Furix Research Site

City

Hialeah

State/Province

Florida

ZIP/Postal Code

33013

Country

United States

Facility Name

Furiex Research Site

City

Hialeah

State/Province

Florida

ZIP/Postal Code

33016

Country

United States

Facility Name

Furiex Research Site

City

Inverness

State/Province

Florida

ZIP/Postal Code

34452

Country

United States

Facility Name

Furiex Research Site

City

Jacksonville

State/Province

Florida

ZIP/Postal Code

32216

Country

United States

Facility Name

Furiex Research Site

City

Kissimmee

State/Province

Florida

ZIP/Postal Code

34741

Country

United States

Facility Name

Furiex Research Site

City

Maitland

State/Province

Florida

ZIP/Postal Code

32751

Country

United States

Facility Name

Furiex Research Site

City

Melbourne

State/Province

Florida

ZIP/Postal Code

32935

Country

United States

Facility Name

Furiex Research Site

City

Miami Springs

State/Province

Florida

ZIP/Postal Code

33166

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33015

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33125

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33126

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33133

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33135

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33144

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33155

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33175

Country

United States

Facility Name

Furiex Research Site

City

Miramar

State/Province

Florida

ZIP/Postal Code

33025

Country

United States

Facility Name

Furiex Research Site

City

Naples

State/Province

Florida

ZIP/Postal Code

34102

Country

United States

Facility Name

Furiex Research Site

City

New Port Richey

State/Province

Florida

ZIP/Postal Code

34653

Country

United States

Facility Name

Furiex Research Site

City

New Smyrna Beach

State/Province

Florida

ZIP/Postal Code

32168

Country

United States

Facility Name

Furiex Research Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32801

Country

United States

Facility Name

Furiex Research Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32806

Country

United States

Facility Name

Furiex Research Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32819

Country

United States

Facility Name

Furiex Research Site

City

Ormond Beach

State/Province

Florida

ZIP/Postal Code

32174

Country

United States

Facility Name

Furiex Research Site

City

Oviedo

State/Province

Florida

ZIP/Postal Code

32765

Country

United States

Facility Name

Furiex Research Site

City

Palm Beach

State/Province

Florida

ZIP/Postal Code

33472

Country

United States

Facility Name

Furiex Research Site

City

Pinellas Park

State/Province

Florida

ZIP/Postal Code

33781

Country

United States

Facility Name

Furiex Research Site

City

Pinellas Park

State/Province

Florida

ZIP/Postal Code

33782

Country

United States

Facility Name

Furiex Research Site

City

Port Orange

State/Province

Florida

ZIP/Postal Code

32129

Country

United States

Facility Name

Furiex Research Site

City

Sanford

State/Province

Florida

ZIP/Postal Code

32771

Country

United States

Facility Name

Furiex Research Site

City

Sebastian

State/Province

Florida

ZIP/Postal Code

32958

Country

United States

Facility Name

Furiex Research Site

City

South Miami

State/Province

Florida

ZIP/Postal Code

33143

Country

United States

Facility Name

Furiex Research Site

City

Tampa

State/Province

Florida

ZIP/Postal Code

33606

Country

United States

Facility Name

Furiex Research Site

City

Tampa

State/Province

Florida

ZIP/Postal Code

33607

Country

United States

Facility Name

Furiex Research Site

City

Venice

State/Province

Florida

ZIP/Postal Code

34292

Country

United States

Facility Name

Furiex Research Site

City

Wellington

State/Province

Florida

ZIP/Postal Code

33414

Country

United States

Facility Name

Furiex Research Site

City

Winter Haven

State/Province

Florida

ZIP/Postal Code

33880

Country

United States

Facility Name

Furiex Research Site

City

Winter Park

State/Province

Florida

ZIP/Postal Code

32792

Country

United States

Facility Name

Furiex Research Site

City

Atlanta

State/Province

Georgia

ZIP/Postal Code

30338

Country

United States

Facility Name

Furiex Research Site

City

Blue Ridge

State/Province

Georgia

ZIP/Postal Code

30513

Country

United States

Facility Name

Furiex Research Site

City

Johns Creek

State/Province

Georgia

ZIP/Postal Code

30097

Country

United States

Facility Name

Furiex Research Site

City

Lilburn

State/Province

Georgia

ZIP/Postal Code

30047

Country

United States

Facility Name

Furiex Research Site

City

Oakwood

State/Province

Georgia

ZIP/Postal Code

30566

Country

United States

Facility Name

Furiex Research Site

City

Perry

State/Province

Georgia

ZIP/Postal Code

31069

Country

United States

Facility Name

Furiex Research Site

City

Snellville

State/Province

Georgia

ZIP/Postal Code

30078

Country

United States

Facility Name

Furiex Research Site

City

Eagle

State/Province

Idaho

ZIP/Postal Code

83616

Country

United States

Facility Name

Furiex Research Site

City

Addison

State/Province

Illinois

ZIP/Postal Code

60101

Country

United States

Facility Name

Furiex Research Site

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60611

Country

United States

Facility Name

Furiex Research Site

City

Morton

State/Province

Illinois

ZIP/Postal Code

61550

Country

United States

Facility Name

Furiex Research Site

City

Brownsburg

State/Province

Indiana

ZIP/Postal Code

46112

Country

United States

Facility Name

Furiex Research Site

City

Evansville

State/Province

Indiana

ZIP/Postal Code

47714

Country

United States

Facility Name

Furiex Research Site

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46202

Country

United States

Facility Name

Furiex Research Site

City

Clive

State/Province

Iowa

ZIP/Postal Code

50325

Country

United States

Facility Name

Furiex Research Site

City

Davenport

State/Province

Iowa

ZIP/Postal Code

52807

Country

United States

Facility Name

Furiex Research Site

City

Iowa City

State/Province

Iowa

ZIP/Postal Code

52242

Country

United States

Facility Name

Furiex Research Site

City

West Des Moines

State/Province

Iowa

ZIP/Postal Code

50266

Country

United States

Facility Name

Furiex Research Site

City

Newton

State/Province

Kansas

ZIP/Postal Code

67114

Country

United States

Facility Name

Furiex Research Site

City

Prairie Village

State/Province

Kansas

ZIP/Postal Code

66206

Country

United States

Facility Name

Furiex Research Site

City

Shawnee Mission

State/Province

Kansas

ZIP/Postal Code

66218

Country

United States

Facility Name

Furiex Research Site

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67203

Country

United States

Facility Name

Furiex Research Site

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67205

Country

United States

Facility Name

Furiex Research Site

City

Crestview Hills

State/Province

Kentucky

ZIP/Postal Code

41017

Country

United States

Facility Name

Furiex Research Site

City

Hawesville

State/Province

Kentucky

ZIP/Postal Code

42348

Country

United States

Facility Name

Furiex Research Site

City

Lexington

State/Province

Kentucky

ZIP/Postal Code

40509

Country

United States

Facility Name

Furiex Research Site

City

Lexington

State/Province

Kentucky

ZIP/Postal Code

40536

Country

United States

Facility Name

Furiex Research Site

City

Louisville

State/Province

Kentucky

ZIP/Postal Code

40202

Country

United States

Facility Name

Furiex Research Site

City

Madisonville

State/Province

Kentucky

ZIP/Postal Code

42431

Country

United States

Facility Name

Furiex Research Site

City

Owensboro

State/Province

Kentucky

ZIP/Postal Code

42303

Country

United States

Facility Name

Furiex Research Site

City

Baker

State/Province

Louisiana

ZIP/Postal Code

70794

Country

United States

Facility Name

Furiex Research Site

City

Covington

State/Province

Louisiana

ZIP/Postal Code

70435

Country

United States

Facility Name

Furiex Research Site

City

Hammond

State/Province

Louisiana

ZIP/Postal Code

70403

Country

United States

Facility Name

Furiex Research Site

City

Metairie

State/Province

Louisiana

ZIP/Postal Code

70006

Country

United States

Facility Name

Furiex Research Site

City

New Orleans

State/Province

Louisiana

ZIP/Postal Code

70124

Country

United States

Facility Name

Furiex Research Site

City

Opelousas

State/Province

Louisiana

ZIP/Postal Code

70570

Country

United States

Facility Name

Furiex Research Site

City

Shreveport

State/Province

Louisiana

ZIP/Postal Code

71101

Country

United States

Facility Name

Furiex Research Site

City

Shreveport

State/Province

Louisiana

ZIP/Postal Code

71105

Country

United States

Facility Name

Furiex Research Site

City

Bangor

State/Province

Maine

ZIP/Postal Code

04401

Country

United States

Facility Name

Furiex Research Site

City

Annapolis

State/Province

Maryland

ZIP/Postal Code

21401

Country

United States

Facility Name

Furiex Research Site

City

Chevy Chase

State/Province

Maryland

ZIP/Postal Code

20815

Country

United States

Facility Name

Furiex Research Site

City

Brockton

State/Province

Massachusetts

ZIP/Postal Code

02301

Country

United States

Facility Name

Furiex Research Site

City

Watertown

State/Province

Massachusetts

ZIP/Postal Code

02472

Country

United States

Facility Name

Furiex Research Site

City

Ann Arbor

State/Province

Michigan

ZIP/Postal Code

48106

Country

United States

Facility Name

Furiex Research Site

City

Southfield

State/Province

Michigan

ZIP/Postal Code

48034

Country

United States

Facility Name

Furiex Research Site

City

Stevensville

State/Province

Michigan

ZIP/Postal Code

49127

Country

United States

Facility Name

Furiex Research Site

City

Chaska

State/Province

Minnesota

ZIP/Postal Code

55318

Country

United States

Facility Name

Furiex Research Site

City

Jackson

State/Province

Mississippi

ZIP/Postal Code

39202

Country

United States

Facility Name

Furiex Research Site

City

Jefferson City

State/Province

Missouri

ZIP/Postal Code

65109

Country

United States

Facility Name

Furiex Research Site

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63128

Country

United States

Facility Name

Furiex Research Site

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63141

Country

United States

Facility Name

Furiex Research Site

City

Saint Peters

State/Province

Missouri

ZIP/Postal Code

63376

Country

United States

Facility Name

Furiex Research Site

City

Billings

State/Province

Montana

ZIP/Postal Code

59102

Country

United States

Facility Name

Furiex Research Site

City

Bellevue

State/Province

Nebraska

ZIP/Postal Code

68005

Country

United States

Facility Name

Furiex Research Site

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68114

Country

United States

Facility Name

Furiex Research Site

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68134

Country

United States

Facility Name

Furiex Research Site

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89106

Country

United States

Facility Name

Furiex Research Site

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89119

Country

United States

Facility Name

Furiex Research Site

City

Collingswood

State/Province

New Jersey

ZIP/Postal Code

08108

Country

United States

Facility Name

Furiex Research Site

City

Edison

State/Province

New Jersey

ZIP/Postal Code

08817

Country

United States

Facility Name

Furiex Research Site

City

Albuquerque

State/Province

New Mexico

ZIP/Postal Code

87106

Country

United States

Facility Name

Furiex Research Site

City

Brooklyn

State/Province

New York

ZIP/Postal Code

11230

Country

United States

Facility Name

Furiex Research Site

City

Endwell

State/Province

New York

ZIP/Postal Code

13760

Country

United States

Facility Name

Furiex Research Site

City

Great Neck

State/Province

New York

ZIP/Postal Code

11023

Country

United States

Facility Name

Furiex Research Site

City

Hartsdale

State/Province

New York

ZIP/Postal Code

10530

Country

United States

Facility Name

Furiex Research Site

City

Kew Gardens

State/Province

New York

ZIP/Postal Code

11415

Country

United States

Facility Name

Furiex Research Site

City

New Windsor

State/Province

New York

ZIP/Postal Code

12553

Country

United States

Facility Name

Furiex Research Site

City

New York

State/Province

New York

ZIP/Postal Code

10016

Country

United States

Facility Name

Furiex Research Site

City

North Massapequa

State/Province

New York

ZIP/Postal Code

11758

Country

United States

Facility Name

Furiex Research Site

City

Poughkeepsie

State/Province

New York

ZIP/Postal Code

12601

Country

United States

Facility Name

Furiex Research Site

City

Asheville

State/Province

North Carolina

ZIP/Postal Code

28801

Country

United States

Facility Name

Furiex Research Site

City

Asheville

State/Province

North Carolina

ZIP/Postal Code

28803

Country

United States

Facility Name

Furiex Research Site

City

Charlotte

State/Province

North Carolina

ZIP/Postal Code

28211

Country

United States

Facility Name

Furiex Research Site

City

Durham

State/Province

North Carolina

ZIP/Postal Code

27713

Country

United States

Facility Name

Furiex Research Site

City

Fayetteville

State/Province

North Carolina

ZIP/Postal Code

28304

Country

United States

Facility Name

Furiex Research Site

City

Greensboro

State/Province

North Carolina

ZIP/Postal Code

27403

Country

United States

Facility Name

Furiex Research Site

City

Hickory

State/Province

North Carolina

ZIP/Postal Code

28602

Country

United States

Facility Name

Furiex Research Site

City

High Point

State/Province

North Carolina

ZIP/Postal Code

27262

Country

United States

Facility Name

Furiex Research Site

City

Kinston

State/Province

North Carolina

ZIP/Postal Code

28501

Country

United States

Facility Name

Furiex Research Site

City

Lenoir

State/Province

North Carolina

ZIP/Postal Code

28645

Country

United States

Facility Name

Furiex Research Site

City

Raleigh

State/Province

North Carolina

ZIP/Postal Code

27609

Country

United States

Facility Name

Furiex Research Site

City

Raleigh

State/Province

North Carolina

ZIP/Postal Code

27612

Country

United States

Facility Name

Furiex Research Site

City

Salisbury

State/Province

North Carolina

ZIP/Postal Code

28144

Country

United States

Facility Name

Furiex Research Site

City

Winston-Salem

State/Province

North Carolina

ZIP/Postal Code

27103

Country

United States

Facility Name

Furiex Research Site

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58103

Country

United States

Facility Name

Furiex Research Site

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58104

Country

United States

Facility Name

Furiex Research Site

City

Beavercreek

State/Province

Ohio

ZIP/Postal Code

45432

Country

United States

Facility Name

Furiex Research Site

City

Berea

State/Province

Ohio

ZIP/Postal Code

44017

Country

United States

Facility Name

Furiex Research Site

City

Centerville

State/Province

Ohio

ZIP/Postal Code

45459

Country

United States

Facility Name

Furiex Research Site

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45212

Country

United States

Facility Name

Furiex Research Site

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45219

Country

United States

Facility Name

Furiex Research Site

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43215

Country

United States

Facility Name

Furiex Research Site

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45415

Country

United States

Facility Name

Furiex Research Site

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45419

Country

United States

Facility Name

Furiex Research Site

City

Englewood

State/Province

Ohio

ZIP/Postal Code

45322

Country

United States

Facility Name

Furiex Research Site

City

Franklin

State/Province

Ohio

ZIP/Postal Code

45005

Country

United States

Facility Name

Furiex Research Site

City

Marion

State/Province

Ohio

ZIP/Postal Code

43302

Country

United States

Facility Name

Furiex Research Site

City

Miamisburg

State/Province

Ohio

ZIP/Postal Code

45342

Country

United States

Facility Name

Furiex Research Site

City

Middleburg Heights

State/Province

Ohio

ZIP/Postal Code

44130

Country

United States

Facility Name

Furiex Research Site

City

Wadsworth

State/Province

Ohio

ZIP/Postal Code

44281

Country

United States

Facility Name

Furiex Research Site

City

Zanesville

State/Province

Ohio

ZIP/Postal Code

43701

Country

United States

Facility Name

Furiex Research Site

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74104

Country

United States

Facility Name

Furiex Research Site

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74135

Country

United States

Facility Name

Furiex Research Site

City

Tulsa

State/Province

Oklahoma

ZIP/Postal Code

74136

Country

United States

Facility Name

Furiex Research Site

City

Belle Vernon

State/Province

Pennsylvania

ZIP/Postal Code

15012

Country

United States

Facility Name

Furiex Research Site

City

Jenkintown

State/Province

Pennsylvania

ZIP/Postal Code

19046

Country

United States

Facility Name

Furiex Research Site

City

Johnstown

State/Province

Pennsylvania

ZIP/Postal Code

15905

Country

United States

Facility Name

Furiex Research Site

City

Lansdale

State/Province

Pennsylvania

ZIP/Postal Code

19446

Country

United States

Facility Name

Furiex Research Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19142

Country

United States

Facility Name

Furiex Research Site

City

Philadelphia

State/Province

Pennsylvania

ZIP/Postal Code

19152

Country

United States

Facility Name

Furiex Research Site

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15236

Country

United States

Facility Name

Furiex Research Site

City

Pittsburgh

State/Province

Pennsylvania

ZIP/Postal Code

15243

Country

United States

Facility Name

Furiex Research Site

City

Uniontown

State/Province

Pennsylvania

ZIP/Postal Code

15401

Country

United States

Facility Name

Furiex Research Site

City

Upper Saint Clair

State/Province

Pennsylvania

ZIP/Postal Code

15241

Country

United States

Facility Name

Furiex Research Site

City

Cumberland

State/Province

Rhode Island

ZIP/Postal Code

02864

Country

United States

Facility Name

Furiex Research Site

City

East Providence

State/Province

Rhode Island

ZIP/Postal Code

02914

Country

United States

Facility Name

Furiex Research Site

City

Anderson

State/Province

South Carolina

ZIP/Postal Code

29621

Country

United States

Facility Name

Furiex Research Site

City

Charleston

State/Province

South Carolina

ZIP/Postal Code

29406

Country

United States

Facility Name

Furiex Research Site

City

Fort Mill

State/Province

South Carolina

ZIP/Postal Code

29707

Country

United States

Facility Name

Furiex Research Site

City

Greenville

State/Province

South Carolina

ZIP/Postal Code

29615

Country

United States

Facility Name

Furiex Research Site

City

Greer

State/Province

South Carolina

ZIP/Postal Code

29650

Country

United States

Facility Name

Furiex Research Site

City

Greer

State/Province

South Carolina

ZIP/Postal Code

29651

Country

United States

Facility Name

Furiex Research Site

City

Myrtle Beach

State/Province

South Carolina

ZIP/Postal Code

29588

Country

United States

Facility Name

Furiex Research Site

City

Myrtle Beach

State/Province

South Carolina

ZIP/Postal Code

29752

Country

United States

Facility Name

Furiex Research Site

City

Simpsonville

State/Province

South Carolina

ZIP/Postal Code

29681

Country

United States

Facility Name

Furiex Research Site

City

Summerville

State/Province

South Carolina

ZIP/Postal Code

29485

Country

United States

Facility Name

Furiex Research Site

City

Bristol

State/Province

Tennessee

ZIP/Postal Code

37620

Country

United States

Facility Name

Furiex Research Site

City

Chattanooga

State/Province

Tennessee

ZIP/Postal Code

37421

Country

United States

Facility Name

Furiex Research Site

City

Clarksville

State/Province

Tennessee

ZIP/Postal Code

37043

Country

United States

Facility Name

Furiex Research Site

City

Columbia

State/Province

Tennessee

ZIP/Postal Code

38401

Country

United States

Facility Name

Furiex Research Site

City

Franklin

State/Province

Tennessee

ZIP/Postal Code

37064

Country

United States

Facility Name

Furiex Research Site

City

Johnson City

State/Province

Tennessee

ZIP/Postal Code

37604

Country

United States

Facility Name

Furiex Research Site

City

Memphis

State/Province

Tennessee

ZIP/Postal Code

38119

Country

United States

Facility Name

Furiex Research Site

City

Smyrna

State/Province

Tennessee

ZIP/Postal Code

37167

Country

United States

Facility Name

Furiex Research Site

City

Austin

State/Province

Texas

ZIP/Postal Code

78745

Country

United States

Facility Name

Furiex Research Site

City

Austin

State/Province

Texas

ZIP/Postal Code

78756

Country

United States

Facility Name

Furiex Research Site

City

Baytown

State/Province

Texas

ZIP/Postal Code

77521

Country

United States

Facility Name

Furiex Research Site

City

Beaumont

State/Province

Texas

ZIP/Postal Code

77701

Country

United States

Facility Name

Furiex Research Site

City

Dallas

State/Province

Texas

ZIP/Postal Code

75224

Country

United States

Facility Name

Furiex Research Site

City

El Paso

State/Province

Texas

ZIP/Postal Code

79905

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77074

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77079

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77089

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77098

Country

United States

Facility Name

Furiex Research Site

City

Marshall

State/Province

Texas

ZIP/Postal Code

75670

Country

United States

Facility Name

Furiex Research Site

City

Plano

State/Province

Texas

ZIP/Postal Code

75024

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78209

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78229

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78258

Country

United States

Facility Name

Furiex Research Site

City

Sugar Land

State/Province

Texas

ZIP/Postal Code

77478

Country

United States

Facility Name

Furiex Research Site

City

Clinton

State/Province

Utah

ZIP/Postal Code

84015

Country

United States

Facility Name

Furiex Research Site

City

Draper

State/Province

Utah

ZIP/Postal Code

84020

Country

United States

Facility Name

Furiex Research Site

City

Logan

State/Province

Utah

ZIP/Postal Code

84341

Country

United States

Facility Name

Furiex Research Site

City

Ogden

State/Province

Utah

ZIP/Postal Code

84405

Country

United States

Facility Name

Furiex Research Site

City

Salt Lake City

State/Province

Utah

ZIP/Postal Code

84102

Country

United States

Facility Name

Furiex Research Site

City

West Jordan

State/Province

Utah

ZIP/Postal Code

84088

Country

United States

Facility Name

Furiex Research Site

City

Lynchburg

State/Province

Virginia

ZIP/Postal Code

24502

Country

United States

Facility Name

Furiex Research Site

City

Richmond

State/Province

Virginia

ZIP/Postal Code

23219

Country

United States

Facility Name

Furiex Research Site

City

Williamsburg

State/Province

Virginia

ZIP/Postal Code

23185

Country

United States

Facility Name

Furiex Research Site

City

Spokane

State/Province

Washington

ZIP/Postal Code

99202

Country

United States

Facility Name

Furiex Research Site

City

Spokane

State/Province

Washington

ZIP/Postal Code

99204

Country

United States

Facility Name

Furiex Research Site

City

Spokane

State/Province

Washington

ZIP/Postal Code

99208

Country

United States

Facility Name

Furiex Research Site

City

Wenatchee

State/Province

Washington

ZIP/Postal Code

98801

Country

United States

Facility Name

Furiex Research Site

City

Morgantown

State/Province

West Virginia

ZIP/Postal Code

26505

Country

United States

Facility Name

Furiex Research Site

City

Wauwatosa

State/Province

Wisconsin

ZIP/Postal Code

53226

Country

United States

Facility Name

Furiex Research Site

City

Kamloops

State/Province

British Columbia

ZIP/Postal Code

V2C 1K7

Country

Canada

Facility Name

Furiex Research Site

City

Kelowna

State/Province

British Columbia

ZIP/Postal Code

V1Y 1Z9

Country

Canada

Facility Name

Furiex Research Site

City

Winnipeg

State/Province

Manitoba

ZIP/Postal Code

R3A 1R9

Country

Canada

Facility Name

Furiex Research Site

City

Bridgewater

State/Province

Nova Scotia

ZIP/Postal Code

B4V 3N2

Country

Canada

Facility Name

Furiex Research Site

City

Halifax

State/Province

Nova Scotia

ZIP/Postal Code

B3K 2M5

Country

Canada

Facility Name

Furiex Research Site

City

Cambridge

State/Province

Ontario

ZIP/Postal Code

N1S 2M6

Country

Canada

Facility Name

Furiex Research Site

City

London

State/Province

Ontario

ZIP/Postal Code

N6A 5R8

Country

Canada

Facility Name

Furiex Research Site

City

Niagara Falls

State/Province

Ontario

ZIP/Postal Code

L2G 1J4

Country

Canada

Facility Name

Furiex Research Site

City

Oshawa

State/Province

Ontario

ZIP/Postal Code

L1H 1B9

Country

Canada

Facility Name

Furiex Research Site

City

Chesterfield

State/Province

Derbyshire

ZIP/Postal Code

S40 4AA

Country

United Kingdom

Facility Name

Furiex Research Site

City

Blackpool

State/Province

Lancashire

ZIP/Postal Code

FY3 7EN

Country

United Kingdom

Facility Name

Furiex Research Site

City

Thornton-Cleveleys

State/Province

Lancashire

ZIP/Postal Code

FY5 3LF

Country

United Kingdom

Facility Name

Furiex Research Site

City

Burbage

State/Province

Leicestershire

ZIP/Postal Code

LE10 2SE

Country

United Kingdom

Facility Name

Furiex Research Site

City

Leamington Spa

State/Province

Warwickshire

ZIP/Postal Code

CV32 4RA

Country

United Kingdom

Facility Name

Furiex Research Site

City

Chippenham

State/Province

Wiltshire

ZIP/Postal Code

SN14 6GT

Country

United Kingdom

Facility Name

Furiex Research Site

City

Bath

ZIP/Postal Code

BA2 3HT

Country

United Kingdom

Facility Name

Furiex Research Site

City

Bath

ZIP/Postal Code

BA2 4BY

Country

United Kingdom

Facility Name

Furiex Research Site

City

Coventry

ZIP/Postal Code

CV6 4DD

Country

United Kingdom

Facility Name

Furiex Research Site

City

Dorking

ZIP/Postal Code

RH4 1SD

Country

United Kingdom

Facility Name

Furiex Research Site

City

Haxey

ZIP/Postal Code

DN9 2HY

Country

United Kingdom

Facility Name

Furiex Research Site

City

London

ZIP/Postal Code

E11 1NR

Country

United Kingdom

Facility Name

Furiex Research Site

City

Shrewsbury

ZIP/Postal Code

SY3 8XQ

Country

United Kingdom

Facility Name

Furiex Research Site

City

Southampton

ZIP/Postal Code

SO16 6YD

Country

United Kingdom

Facility Name

Furiex Research Site

City

Strensall

ZIP/Postal Code

YO32 5UA

Country

United Kingdom

Facility Name

Furiex Research Site

City

Thornton

ZIP/Postal Code

FY5 2TZ

Country

United Kingdom

Facility Name

Furiex Research Site

City

Torpoint

ZIP/Postal Code

PL11 2JW

Country

United Kingdom

12. IPD Sharing Statement

Citations:

PubMed Identifier

28167156

Citation

Fant RV, Henningfield JE, Cash BD, Dove LS, Covington PS. Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea. Clin Gastroenterol Hepatol. 2017 Jul;15(7):1021-1029.e6. doi: 10.1016/j.cgh.2017.01.026. Epub 2017 Feb 3.

Results Reference

derived

PubMed Identifier

26789872

Citation

Lembo AJ, Lacy BE, Zuckerman MJ, Schey R, Dove LS, Andrae DA, Davenport JM, McIntyre G, Lopez R, Turner L, Covington PS. Eluxadoline for Irritable Bowel Syndrome with Diarrhea. N Engl J Med. 2016 Jan 21;374(3):242-53. doi: 10.1056/NEJMoa1505180.

Results Reference

derived

Learn more about this trial

Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

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Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

Irritable Bowel Syndrome

About this trial

Eligibility Criteria

Sites / Locations

Arms of the Study

Arm 1

Arm 2

Arm 3

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

1. Study Identification

2. Study Status

3. Sponsor/Collaborators

4. Oversight

5. Study Description

6. Conditions and Keywords

7. Study Design

8. Arms, Groups, and Interventions

10. Eligibility

12. IPD Sharing Statement

Learn more about this trial