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Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea

Primary Purpose

Irritable Bowel Syndrome

Status

Completed

Phase

Phase 2

Locations

United States

Study Type

Interventional

Intervention

Eluxadoline

Placebo

About this trial

This is an interventional treatment trial for Irritable Bowel Syndrome focused on measuring Irritable bowel syndrome with diarrhea, Irritable bowel syndrome, Diarrhea predominant irritable bowel syndrome, Colonic diseases, Colonic diseases, functional, Digestive system disease, Gastrointestinal disease, Intestinal disease, Colonic pseudo-obstruction, Diarrhea, Signs and Symptoms, Digestive

Eligibility Criteria

18 Years - 65 Years (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Key Inclusion Criteria:

Patient has a diagnosis of IBS by Rome III criteria with a subtype of diarrhea
Female patients must be:
postmenopausal, defined as amenorrhea for at least 2 years at Prescreening,
surgically sterile (have had a hysterectomy or bilateral oophorectomy, tubal ligation, or otherwise be incapable of pregnancy),
abstinent, or
if sexually active, be practicing an effective method of birth control.

Key Exclusion Criteria:

Patient has a diagnosis of IBS by Rome III criteria with a subtype of constipation, mixed IBS, or unsubtyped IBS
Patient has a history of inflammatory or immune-mediated gastrointestinal (GI) disorders including inflammatory bowel disease (ie, Crohn's disease, ulcerative colitis) and celiac disease
Patient has a history of diverticulitis within 6 months prior to Prescreening
Patient has a history of intestinal obstruction, stricture, toxic megacolon, GI perforation, fecal impaction, gastric banding, bariatric surgery, adhesions, ischemic colitis, impaired intestinal circulation (eg, aortoiliac disease), thrombophlebitis of a major vein, or hypercoagulable states.

Other protocol-specific eligibility criteria may apply.

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm 5

Arm Type

Experimental

Placebo Comparator

Arm Label

Eluxadoline 5 mg

Eluxadoline 25 mg

Eluxadoline 100 mg

Eluxadoline 200 mg

Placebo

Arm Description

Eluxadoline 5 mg tablets, orally, twice daily for up to 12 weeks.

Eluxadoline 25 mg tablets, orally, twice daily for up to 12 weeks. .

Eluxadoline 100 mg tablets, orally, twice daily for up to 12 weeks.

Eluxadoline 200 mg tablets, orally, twice daily for up to 12 weeks.

Eluxadoline placebo matching tablets, orally, twice daily for up to 12 weeks.

Outcomes

Primary Outcome Measures

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain and Daily Stool Consistency Scores at Week 4

Composite responders were defined as participants who completed at least 5 out of 7 days with diary entries during the interval of interest and met both of the following criteria: 1) Average daily pain response scores over the past week improved by ≥30% and at least 2 points as compared with the baseline average pain score (average of daily worst abdominal pain the week prior to randomization), 2) Bristol Stool Scale (BSS) score of 3 or 4 on 66% of reported days in the past week. Abdominal pain was assessed on an 11-point scale where: 0=no pain to 10=worst pain imaginable. Stool consistency was assessed using the BSS 7-point scale where: 1=separate hard lumps, 2=sausage shaped but lumpy, 3=sausage-like with cracks on the surface, 4=sausage-like but smooth and soft, 5=soft blobs with clear cut edges, 6=fluffy pieces with ragged edges, and 7=watery with no solid pieces.

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain and Daily Stool Consistency Scores at Week 12

Composite responders were defined as participants who completed at least 5 out of 7 days with diary entries during the interval of interest and met both of the following criteria: 1) Average daily pain response scores over the past week improved by ≥30% and at least 2 points as compared with the baseline average pain score (average of daily worst abdominal pain the week prior to randomization), 2) Bristol Stool Scale (BSS) score of 3 or 4 on 66% of reported days in the past week. The participant recorded their abdominal pain in a daily diary using an 11-point scale where: 0=no pain to 10=worst pain imaginable. The participant recorded stool consistency in a daily diary using the BSS 7-point scale where: 1=separate hard lumps, 2=sausage shaped but lumpy, 3=sausage-like with cracks on the surface, 4=sausage-like but smooth and soft, 5=soft blobs with clear cut edges, 6=fluffy pieces with ragged edges, and 7=watery with no solid pieces.

Secondary Outcome Measures

Change From Baseline in the Weekly Pain Scores

The participant recorded their worst daily pain score in a diary using an 11-point scale where: 0=no pain to 10=worst pain imaginable. The daily scores over the previous week were averaged. A negative change from Baseline indicates improvement.

Change From Baseline in Weekly BSS Scores

The patient recorded stool consistency in a daily diary using the BSS 7-point scale where: 1=hard stool to 7=watery diarrhea. The daily scores over the previous week were averaged. A negative change from Baseline indicates improvement.

Change From Baseline in the Number of Daily Bowel Movements

Participants recorded the number of bowel movements in a daily diary at the same time each day. The number of daily bowel movements over the previous week were averaged. A negative change from Baseline indicates improvement.

Percentage of Participants With Response Based on Participants Achieving Prespecified Improvement in Symptoms for at Least 50% of the Time

Responders were participants that met both of the following criteria on the same week for at least 50% of time on study: 1) average of daily pain scores over the past week improved by ≥30% compared with baseline average in pain score, 2) ≥50% reduction in the number of days over the past week with a BSS score ≥5 compared with Baseline. Participants must also have had at least 5/7 days diary entry to be considered a responder for that week. Abdominal pain was assessed on an 11-point scale where a score of 0=no pain to 10=worst pain imaginable. Stool consistency was assessed using the BSS 7-point scale where: 1=separate hard lumps to 7=watery with no solid pieces. Response rates (percentage of participants) are based on model estimates from the logistic regression.

Full Information

NCT ID

NCT01130272

First Posted

May 24, 2010

Last Updated

September 30, 2019

Sponsor

Furiex Pharmaceuticals, Inc

1. Study Identification

Unique Protocol Identification Number

NCT01130272

Brief Title

Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea

Official Title

A Randomized, Double-blind, Placebo-controlled, Parallel Group, Dose Ranging, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-27018966 in the Treatment of Patients With Irritable Bowel Syndrome With Diarrhea

Study Type

Interventional

2. Study Status

Record Verification Date

September 2019

Overall Recruitment Status

Completed

Study Start Date

April 28, 2010 (Actual)

Primary Completion Date

July 14, 2011 (Actual)

Study Completion Date

July 14, 2011 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Sponsor

Name of the Sponsor

Furiex Pharmaceuticals, Inc

4. Oversight

Data Monitoring Committee

5. Study Description

Brief Summary

The purpose of this study is to determine the efficacy, safety, and tolerability of different doses of JNJ-27018966 (eluxadoline) compared with placebo in the treatment of patients with irritable bowel syndrome with diarrhea (IBS-d).

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Irritable Bowel Syndrome

Keywords

Irritable bowel syndrome with diarrhea, Irritable bowel syndrome, Diarrhea predominant irritable bowel syndrome, Colonic diseases, Colonic diseases, functional, Digestive system disease, Gastrointestinal disease, Intestinal disease, Colonic pseudo-obstruction, Diarrhea, Signs and Symptoms, Digestive

7. Study Design

Primary Purpose

Treatment

Study Phase

Phase 2

Interventional Study Model

Parallel Assignment

Masking

ParticipantCare ProviderInvestigatorOutcomes Assessor

Allocation

Randomized

Enrollment

807 (Actual)

8. Arms, Groups, and Interventions

Arm Title

Eluxadoline 5 mg

Arm Type

Experimental

Arm Description

Eluxadoline 5 mg tablets, orally, twice daily for up to 12 weeks.

Arm Title

Eluxadoline 25 mg

Arm Type

Experimental

Arm Description

Eluxadoline 25 mg tablets, orally, twice daily for up to 12 weeks. .

Arm Title

Eluxadoline 100 mg

Arm Type

Experimental

Arm Description

Eluxadoline 100 mg tablets, orally, twice daily for up to 12 weeks.

Arm Title

Eluxadoline 200 mg

Arm Type

Experimental

Arm Description

Eluxadoline 200 mg tablets, orally, twice daily for up to 12 weeks.

Arm Title

Placebo

Arm Type

Placebo Comparator

Arm Description

Eluxadoline placebo matching tablets, orally, twice daily for up to 12 weeks.

Intervention Type

Drug

Intervention Name(s)

Eluxadoline

Other Intervention Name(s)

JNJ-27018966

Intervention Description

Tablets, orally, twice daily.

Intervention Type

Drug

Intervention Name(s)

Placebo

Intervention Description

Matching placebo oral tablets twice daily.

Primary Outcome Measure Information:

Title

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain and Daily Stool Consistency Scores at Week 4

Description

Time Frame

Baseline (Week prior to Randomization) to Week 4

Title

Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain and Daily Stool Consistency Scores at Week 12

Description

Composite responders were defined as participants who completed at least 5 out of 7 days with diary entries during the interval of interest and met both of the following criteria: 1) Average daily pain response scores over the past week improved by ≥30% and at least 2 points as compared with the baseline average pain score (average of daily worst abdominal pain the week prior to randomization), 2) Bristol Stool Scale (BSS) score of 3 or 4 on 66% of reported days in the past week. The participant recorded their abdominal pain in a daily diary using an 11-point scale where: 0=no pain to 10=worst pain imaginable. The participant recorded stool consistency in a daily diary using the BSS 7-point scale where: 1=separate hard lumps, 2=sausage shaped but lumpy, 3=sausage-like with cracks on the surface, 4=sausage-like but smooth and soft, 5=soft blobs with clear cut edges, 6=fluffy pieces with ragged edges, and 7=watery with no solid pieces.

Time Frame

Baseline (Week prior to Randomization) to Week 12

Secondary Outcome Measure Information:

Title

Change From Baseline in the Weekly Pain Scores

Description

Time Frame

Baseline (Week Prior to Randomization) to Weeks 4, 8, and 12

Title

Change From Baseline in Weekly BSS Scores

Description

Time Frame

Baseline (Week prior to Randomization) to Weeks 4, 8, and 12

Title

Change From Baseline in the Number of Daily Bowel Movements

Description

Time Frame

Baseline (Week prior to Randomization) to Weeks 4, 8, and 12

Title

Percentage of Participants With Response Based on Participants Achieving Prespecified Improvement in Symptoms for at Least 50% of the Time

Description

Time Frame

Baseline (Week Prior to Randomization) to Weeks 1-12

10. Eligibility

Sex

All

Minimum Age & Unit of Time

18 Years

Maximum Age & Unit of Time

65 Years

Accepts Healthy Volunteers

Eligibility Criteria

Key Inclusion Criteria: Patient has a diagnosis of IBS by Rome III criteria with a subtype of diarrhea Female patients must be: postmenopausal, defined as amenorrhea for at least 2 years at Prescreening, surgically sterile (have had a hysterectomy or bilateral oophorectomy, tubal ligation, or otherwise be incapable of pregnancy), abstinent, or if sexually active, be practicing an effective method of birth control. Key Exclusion Criteria: Patient has a diagnosis of IBS by Rome III criteria with a subtype of constipation, mixed IBS, or unsubtyped IBS Patient has a history of inflammatory or immune-mediated gastrointestinal (GI) disorders including inflammatory bowel disease (ie, Crohn's disease, ulcerative colitis) and celiac disease Patient has a history of diverticulitis within 6 months prior to Prescreening Patient has a history of intestinal obstruction, stricture, toxic megacolon, GI perforation, fecal impaction, gastric banding, bariatric surgery, adhesions, ischemic colitis, impaired intestinal circulation (eg, aortoiliac disease), thrombophlebitis of a major vein, or hypercoagulable states. Other protocol-specific eligibility criteria may apply.

Facility Information:

Facility Name

Furiex Research Site

City

Anniston

State/Province

Alabama

ZIP/Postal Code

36207

Country

United States

Facility Name

Furiex Research Site

City

Birmingham

State/Province

Alabama

ZIP/Postal Code

35216

Country

United States

Facility Name

Furiex Research Site

City

Birmingham

State/Province

Alabama

ZIP/Postal Code

35235

Country

United States

Facility Name

Furiex Research Site

City

Dothan

State/Province

Alabama

ZIP/Postal Code

36305

Country

United States

Facility Name

Furiex Research Site

City

Huntsville

State/Province

Alabama

ZIP/Postal Code

35801

Country

United States

Facility Name

Furiex Research Site

City

Huntsville

State/Province

Alabama

ZIP/Postal Code

35802

Country

United States

Facility Name

Furiex Research Site

City

Mobile

State/Province

Alabama

ZIP/Postal Code

36693

Country

United States

Facility Name

Furiex Research Site

City

Montgomery

State/Province

Alabama

ZIP/Postal Code

36109

Country

United States

Facility Name

Furiex Research Site

City

Pell City

State/Province

Alabama

ZIP/Postal Code

35128

Country

United States

Facility Name

Furiex Research Site

City

Chandler

State/Province

Arizona

ZIP/Postal Code

85224

Country

United States

Facility Name

Furiex Research Site

City

Glendale

State/Province

Arizona

ZIP/Postal Code

85308

Country

United States

Facility Name

Furiex Research Site

City

Mesa

State/Province

Arizona

ZIP/Postal Code

85203

Country

United States

Facility Name

Furiex Research Site

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85018

Country

United States

Facility Name

Furiex Research Site

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85020

Country

United States

Facility Name

Furiex Research Site

City

Phoenix

State/Province

Arizona

ZIP/Postal Code

85050

Country

United States

Facility Name

Furiex Research Site

City

Tempe

State/Province

Arizona

ZIP/Postal Code

85282

Country

United States

Facility Name

Furiex Research Site

City

Tempe

State/Province

Arizona

ZIP/Postal Code

85283

Country

United States

Facility Name

Furiex Research Site

City

Tucson

State/Province

Arizona

ZIP/Postal Code

85704

Country

United States

Facility Name

Furiex Research Site

City

Tucson

State/Province

Arizona

ZIP/Postal Code

85710

Country

United States

Facility Name

Furiex Research Site

City

Jonesboro

State/Province

Arkansas

ZIP/Postal Code

72401

Country

United States

Facility Name

Furiex Research Site

City

Little Rock

State/Province

Arkansas

ZIP/Postal Code

72211

Country

United States

Facility Name

Furiex Research Site

City

Searcy

State/Province

Arkansas

ZIP/Postal Code

72143

Country

United States

Facility Name

Furiex Research Site

City

Sherwood

State/Province

Arkansas

ZIP/Postal Code

72120

Country

United States

Facility Name

Furiex Research Site

City

Aliso Viejo

State/Province

California

ZIP/Postal Code

92656

Country

United States

Facility Name

Furiex Research Site

City

Anaheim

State/Province

California

ZIP/Postal Code

92801

Country

United States

Facility Name

Furiex Research Site

City

Azusa

State/Province

California

ZIP/Postal Code

91702

Country

United States

Facility Name

Furiex Research Site

City

Burbank

State/Province

California

ZIP/Postal Code

91505

Country

United States

Facility Name

Furiex Research Site

City

Carlsbad

State/Province

California

ZIP/Postal Code

92008

Country

United States

Facility Name

Furiex Research Site

City

Encinitas

State/Province

California

ZIP/Postal Code

92024

Country

United States

Facility Name

Furiex Research Site

City

Garden Grove

State/Province

California

ZIP/Postal Code

92840

Country

United States

Facility Name

Furiex Research Site

City

Garden Grove

State/Province

California

ZIP/Postal Code

92843

Country

United States

Facility Name

Furiex Research Site

City

Inglewood

State/Province

California

ZIP/Postal Code

90301

Country

United States

Facility Name

Furiex Research Site

City

Laguna Hills

State/Province

California

ZIP/Postal Code

92653

Country

United States

Facility Name

Furiex Research Site

City

Long Beach

State/Province

California

ZIP/Postal Code

90806

Country

United States

Facility Name

Furiex Research Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90015

Country

United States

Facility Name

Furiex Research Site

City

Los Angeles

State/Province

California

ZIP/Postal Code

90045

Country

United States

Facility Name

Furiex Research Site

City

Murietta

State/Province

California

ZIP/Postal Code

92562

Country

United States

Facility Name

Furiex Research Site

City

Oakland

State/Province

California

ZIP/Postal Code

94609

Country

United States

Facility Name

Furiex Research Site

City

Orange

State/Province

California

ZIP/Postal Code

92869

Country

United States

Facility Name

Furiex Research Site

City

Sacramento

State/Province

California

ZIP/Postal Code

95825

Country

United States

Facility Name

Furiex Research Site

City

San Carlos

State/Province

California

ZIP/Postal Code

94070

Country

United States

Facility Name

Furiex Research Site

City

San Diego

State/Province

California

ZIP/Postal Code

92103-6204

Country

United States

Facility Name

Furiex Research Site

City

San Diego

State/Province

California

ZIP/Postal Code

92120

Country

United States

Facility Name

Furiex Research Site

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80904

Country

United States

Facility Name

Furiex Research Site

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80907

Country

United States

Facility Name

Furiex Research Site

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80920

Country

United States

Facility Name

Furiex Research Site

City

Colorado Springs

State/Province

Colorado

ZIP/Postal Code

80922

Country

United States

Facility Name

Furiex Research Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80222

Country

United States

Facility Name

Furiex Research Site

City

Denver

State/Province

Colorado

ZIP/Postal Code

80239

Country

United States

Facility Name

Furiex Research Site

City

Lakewood

State/Province

Colorado

ZIP/Postal Code

80215

Country

United States

Facility Name

Furiex Research Site

City

Littleton

State/Province

Colorado

ZIP/Postal Code

80120

Country

United States

Facility Name

Furiex Research Site

City

Thornton

State/Province

Colorado

ZIP/Postal Code

80229

Country

United States

Facility Name

Furiex Research Site

City

Bristol

State/Province

Connecticut

ZIP/Postal Code

06010

Country

United States

Facility Name

Furiex Research Site

City

Waterbury

State/Province

Connecticut

ZIP/Postal Code

06708

Country

United States

Facility Name

Furiex Research Site

City

Aventura

State/Province

Florida

ZIP/Postal Code

33916

Country

United States

Facility Name

Furiex Research Site

City

Boca Raton

State/Province

Florida

ZIP/Postal Code

33428

Country

United States

Facility Name

Furiex Research Site

City

Boca Raton

State/Province

Florida

ZIP/Postal Code

33432

Country

United States

Facility Name

Furiex Research Site

City

Bradenton

State/Province

Florida

ZIP/Postal Code

34208

Country

United States

Facility Name

Furiex Research Site

City

Brandon

State/Province

Florida

ZIP/Postal Code

33511

Country

United States

Facility Name

Furiex Research Site

City

Chipley

State/Province

Florida

ZIP/Postal Code

32428

Country

United States

Facility Name

Furiex Research Site

City

DeLand

State/Province

Florida

ZIP/Postal Code

32720

Country

United States

Facility Name

Furiex Research Site

City

Delray Beach

State/Province

Florida

ZIP/Postal Code

33484

Country

United States

Facility Name

Furiex Research Site

City

Doral

State/Province

Florida

ZIP/Postal Code

33172

Country

United States

Facility Name

Furiex Research Site

City

Fort Lauderdale

State/Province

Florida

ZIP/Postal Code

33306

Country

United States

Facility Name

Furiex Research Site

City

Hialeah

State/Province

Florida

ZIP/Postal Code

33013

Country

United States

Facility Name

Furiex Research Site

City

Hialeah

State/Province

Florida

ZIP/Postal Code

33016

Country

United States

Facility Name

Furiex Research Site

City

Inverness

State/Province

Florida

ZIP/Postal Code

34452

Country

United States

Facility Name

Furiex Research Site

City

Jacksonville

State/Province

Florida

ZIP/Postal Code

32209

Country

United States

Facility Name

Furiex Research Site

City

Jacksonville

State/Province

Florida

ZIP/Postal Code

32256

Country

United States

Facility Name

Furiex Research Site

City

Jupiter

State/Province

Florida

ZIP/Postal Code

33458

Country

United States

Facility Name

Furiex Research Site

City

Kissimmee

State/Province

Florida

ZIP/Postal Code

34741

Country

United States

Facility Name

Furiex Research Site

City

Largo

State/Province

Florida

ZIP/Postal Code

33777

Country

United States

Facility Name

Furiex Research Site

City

Lauderdale Lakes

State/Province

Florida

ZIP/Postal Code

33319

Country

United States

Facility Name

Furiex Research Site

City

Melbourne

State/Province

Florida

ZIP/Postal Code

32935

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33126

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33135

Country

United States

Facility Name

Furiex Research Site

City

Miami

State/Province

Florida

ZIP/Postal Code

33155

Country

United States

Facility Name

Furiex Research Site

City

Naples

State/Province

Florida

ZIP/Postal Code

34102

Country

United States

Facility Name

Furiex Research Site

City

Naples

State/Province

Florida

ZIP/Postal Code

34109

Country

United States

Facility Name

Furiex Research Site

City

New Port Richey

State/Province

Florida

ZIP/Postal Code

34652

Country

United States

Facility Name

Furiex Research Site

City

New Port Richey

State/Province

Florida

ZIP/Postal Code

34655

Country

United States

Facility Name

Furiex Research Site

City

New Smyrna Beach

State/Province

Florida

ZIP/Postal Code

32168

Country

United States

Facility Name

Furiex Research Site

City

Orlando

State/Province

Florida

ZIP/Postal Code

32837

Country

United States

Facility Name

Furiex Research Site

City

Plantation

State/Province

Florida

ZIP/Postal Code

33317

Country

United States

Facility Name

Furiex Research Site

City

Port Orange

State/Province

Florida

ZIP/Postal Code

32129

Country

United States

Facility Name

Furiex Research Site

City

Saint Petersburg

State/Province

Florida

ZIP/Postal Code

33709

Country

United States

Facility Name

Furiex Research Site

City

South Miami

State/Province

Florida

ZIP/Postal Code

33143

Country

United States

Facility Name

Furiex Research Site

City

Tampa

State/Province

Florida

ZIP/Postal Code

33606

Country

United States

Facility Name

Furiex Research Site

City

Tampa

State/Province

Florida

ZIP/Postal Code

33613

Country

United States

Facility Name

Furiex Research Site

City

Atlanta

State/Province

Georgia

ZIP/Postal Code

30312

Country

United States

Facility Name

Furiex Research Site

City

Atlanta

State/Province

Georgia

ZIP/Postal Code

30338

Country

United States

Facility Name

Furiex Research Site

City

Columbus

State/Province

Georgia

ZIP/Postal Code

31904

Country

United States

Facility Name

Furiex Research Site

City

Duluth

State/Province

Georgia

ZIP/Postal Code

30096

Country

United States

Facility Name

Furiex Research Site

City

Macon

State/Province

Georgia

ZIP/Postal Code

31201

Country

United States

Facility Name

Furiex Research Site

City

Marietta

State/Province

Georgia

ZIP/Postal Code

30066

Country

United States

Facility Name

Furiex Research Site

City

Newnan

State/Province

Georgia

ZIP/Postal Code

30263

Country

United States

Facility Name

Furiex Research Site

City

Rome

State/Province

Georgia

ZIP/Postal Code

30165

Country

United States

Facility Name

Furiex Research Site

City

Sandy Springs

State/Province

Georgia

ZIP/Postal Code

30328

Country

United States

Facility Name

Furiex Research Site

City

Savannah

State/Province

Georgia

ZIP/Postal Code

31406

Country

United States

Facility Name

Furiex Research Site

City

Boise

State/Province

Idaho

ZIP/Postal Code

83702

Country

United States

Facility Name

Furiex Research Site

City

Boise

State/Province

Idaho

ZIP/Postal Code

83704

Country

United States

Facility Name

Furiex Research Site

City

Idaho Falls

State/Province

Idaho

ZIP/Postal Code

83404

Country

United States

Facility Name

Furiex Research Site

City

Meridian

State/Province

Idaho

ZIP/Postal Code

83642

Country

United States

Facility Name

Furiex Research Site

City

Nampa

State/Province

Idaho

ZIP/Postal Code

83686

Country

United States

Facility Name

Furiex Research Site

City

Champaign

State/Province

Illinois

ZIP/Postal Code

61820

Country

United States

Facility Name

Furiex Research Site

City

Chicago

State/Province

Illinois

ZIP/Postal Code

60634

Country

United States

Facility Name

Furiex Research Site

City

Morton

State/Province

Illinois

ZIP/Postal Code

61550

Country

United States

Facility Name

Furiex Research Site

City

Anderson

State/Province

Indiana

ZIP/Postal Code

46016

Country

United States

Facility Name

Furiex Research Site

City

Bloomington

State/Province

Indiana

ZIP/Postal Code

47403

Country

United States

Facility Name

Furiex Research Site

City

Evansville

State/Province

Indiana

ZIP/Postal Code

47714

Country

United States

Facility Name

Furiex Research Site

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46205

Country

United States

Facility Name

Furiex Research Site

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46237

Country

United States

Facility Name

Furiex Research Site

City

Indianapolis

State/Province

Indiana

ZIP/Postal Code

46250

Country

United States

Facility Name

Furiex Research Site

City

Lenexa

State/Province

Kansas

ZIP/Postal Code

66215

Country

United States

Facility Name

Furiex Research Site

City

Mission

State/Province

Kansas

ZIP/Postal Code

66202

Country

United States

Facility Name

Furiex Research Site

City

Overland Park

State/Province

Kansas

ZIP/Postal Code

66202

Country

United States

Facility Name

Furiex Research Site

City

Overland Park

State/Province

Kansas

ZIP/Postal Code

66215

Country

United States

Facility Name

Furiex Research Site

City

Topeka

State/Province

Kansas

ZIP/Postal Code

66606

Country

United States

Facility Name

Furiex Research Site

City

Wichita

State/Province

Kansas

ZIP/Postal Code

67203

Country

United States

Facility Name

Furiex Research Site

City

Bowling Green

State/Province

Kentucky

ZIP/Postal Code

42101

Country

United States

Facility Name

Furiex Research Site

City

Lexington

State/Province

Kentucky

ZIP/Postal Code

40504

Country

United States

Facility Name

Furiex Research Site

City

Louisville

State/Province

Kentucky

ZIP/Postal Code

40202

Country

United States

Facility Name

Furiex Research Site

City

Metairie

State/Province

Louisiana

ZIP/Postal Code

70006

Country

United States

Facility Name

Furiex Research Site

City

Monroe

State/Province

Louisiana

ZIP/Postal Code

71201

Country

United States

Facility Name

Furiex Research Site

City

Opelousas

State/Province

Louisiana

ZIP/Postal Code

70570

Country

United States

Facility Name

Furiex Research Site

City

Shreveport

State/Province

Louisiana

ZIP/Postal Code

71101

Country

United States

Facility Name

Furiex Research Site

City

Shreveport

State/Province

Louisiana

ZIP/Postal Code

71103

Country

United States

Facility Name

Furiex Research Site

City

Annapolis

State/Province

Maryland

ZIP/Postal Code

21401

Country

United States

Facility Name

Furiex Research Site

City

Chevy Chase

State/Province

Maryland

ZIP/Postal Code

20815

Country

United States

Facility Name

Furiex Research Site

City

Hollywood

State/Province

Maryland

ZIP/Postal Code

20636

Country

United States

Facility Name

Furiex Research Site

City

Laurel

State/Province

Maryland

ZIP/Postal Code

20707

Country

United States

Facility Name

Furiex Research Site

City

Lutherville

State/Province

Maryland

ZIP/Postal Code

21093

Country

United States

Facility Name

Furiex Research Site

City

Prince Frederick

State/Province

Maryland

ZIP/Postal Code

20678

Country

United States

Facility Name

Furiex Research Site

City

Rockville

State/Province

Maryland

ZIP/Postal Code

20850

Country

United States

Facility Name

Furiex Research Site

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02114

Country

United States

Facility Name

Furiex Research Site

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02135

Country

United States

Facility Name

Furiex Research Site

City

Boston

State/Province

Massachusetts

ZIP/Postal Code

02215

Country

United States

Facility Name

Furiex Research Site

City

Brockton

State/Province

Massachusetts

ZIP/Postal Code

02301

Country

United States

Facility Name

Furiex Research Site

City

Hyannis

State/Province

Massachusetts

ZIP/Postal Code

02601

Country

United States

Facility Name

Furiex Research Site

City

Springfield

State/Province

Massachusetts

ZIP/Postal Code

01105

Country

United States

Facility Name

Furiex Research Site

City

Chesterfield

State/Province

Michigan

ZIP/Postal Code

48047

Country

United States

Facility Name

Furiex Research Site

City

Interlochen

State/Province

Michigan

ZIP/Postal Code

49643

Country

United States

Facility Name

Furiex Research Site

City

Kalamazoo

State/Province

Michigan

ZIP/Postal Code

49009

Country

United States

Facility Name

Furiex Research Site

City

Novi

State/Province

Michigan

ZIP/Postal Code

48377

Country

United States

Facility Name

Furiex Research Site

City

Troy

State/Province

Michigan

ZIP/Postal Code

48098

Country

United States

Facility Name

Furiex Research Site

City

Chaska

State/Province

Minnesota

ZIP/Postal Code

55318

Country

United States

Facility Name

Furiex Research Site

City

Jackson

State/Province

Mississippi

ZIP/Postal Code

39202

Country

United States

Facility Name

Furiex Research Site

City

Tupelo

State/Province

Mississippi

ZIP/Postal Code

38801

Country

United States

Facility Name

Furiex Research Site

City

Mexico

State/Province

Missouri

ZIP/Postal Code

65265

Country

United States

Facility Name

Furiex Research Site

City

Saint Louis

State/Province

Missouri

ZIP/Postal Code

63141

Country

United States

Facility Name

Furiex Research Site

City

Saint Peters

State/Province

Missouri

ZIP/Postal Code

63376

Country

United States

Facility Name

Furiex Research Site

City

Billings

State/Province

Montana

ZIP/Postal Code

59102

Country

United States

Facility Name

Furiex Research Site

City

Bozeman

State/Province

Montana

ZIP/Postal Code

59718

Country

United States

Facility Name

Furiex Research Site

City

Bellevue

State/Province

Nebraska

ZIP/Postal Code

68005

Country

United States

Facility Name

Furiex Research Site

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68114

Country

United States

Facility Name

Furiex Research Site

City

Omaha

State/Province

Nebraska

ZIP/Postal Code

68144

Country

United States

Facility Name

Furiex Research Site

City

Henderson

State/Province

Nevada

ZIP/Postal Code

89052

Country

United States

Facility Name

Furiex Research Site

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89106

Country

United States

Facility Name

Furiex Research Site

City

Las Vegas

State/Province

Nevada

ZIP/Postal Code

89183

Country

United States

Facility Name

Furiex Research Site

City

Atco

State/Province

New Jersey

ZIP/Postal Code

08044

Country

United States

Facility Name

Furiex Research Site

City

Blackwood

State/Province

New Jersey

ZIP/Postal Code

08012

Country

United States

Facility Name

Furiex Research Site

City

Elizabeth

State/Province

New Jersey

ZIP/Postal Code

07202

Country

United States

Facility Name

Furiex Research Site

City

Marlton

State/Province

New Jersey

ZIP/Postal Code

08053

Country

United States

Facility Name

Furiex Research Site

City

Morristown

State/Province

New Jersey

ZIP/Postal Code

07960

Country

United States

Facility Name

Furiex Research Site

City

South Bound Brook

State/Province

New Jersey

ZIP/Postal Code

08880

Country

United States

Facility Name

Furiex Research Site

City

Vineland

State/Province

New Jersey

ZIP/Postal Code

08360

Country

United States

Facility Name

Furiex Research Site

City

Albuquerque

State/Province

New Mexico

ZIP/Postal Code

87102

Country

United States

Facility Name

Furiex Research Site

City

Albuquerque

State/Province

New Mexico

ZIP/Postal Code

87108

Country

United States

Facility Name

Furiex Research Site

City

Binghamton

State/Province

New York

ZIP/Postal Code

13903

Country

United States

Facility Name

Furiex Research Site

City

Brooklyn

State/Province

New York

ZIP/Postal Code

11214

Country

United States

Facility Name

Furiex Research Site

City

Brooklyn

State/Province

New York

ZIP/Postal Code

11230

Country

United States

Facility Name

Furiex Research Site

City

Great Neck

State/Province

New York

ZIP/Postal Code

11021

Country

United States

Facility Name

Furiex Research Site

City

Great Neck

State/Province

New York

ZIP/Postal Code

11023

Country

United States

Facility Name

Furiex Research Site

City

Mineola

State/Province

New York

ZIP/Postal Code

11501

Country

United States

Facility Name

Furiex Research Site

City

New York

State/Province

New York

ZIP/Postal Code

10016

Country

United States

Facility Name

Furiex Research Site

City

Boone

State/Province

North Carolina

ZIP/Postal Code

28607

Country

United States

Facility Name

Furiex Research Site

City

Chapel Hill

State/Province

North Carolina

ZIP/Postal Code

27599

Country

United States

Facility Name

Furiex Research Site

City

Charlotte

State/Province

North Carolina

ZIP/Postal Code

28209

Country

United States

Facility Name

Furiex Research Site

City

Charlotte

State/Province

North Carolina

ZIP/Postal Code

28277

Country

United States

Facility Name

Furiex Research Site

City

Fayetteville

State/Province

North Carolina

ZIP/Postal Code

28304

Country

United States

Facility Name

Furiex Research Site

City

Greensboro

State/Province

North Carolina

ZIP/Postal Code

27401

Country

United States

Facility Name

Furiex Research Site

City

Greensboro

State/Province

North Carolina

ZIP/Postal Code

27403

Country

United States

Facility Name

Furiex Research Site

City

Greenville

State/Province

North Carolina

ZIP/Postal Code

27834

Country

United States

Facility Name

Furiex Research Site

City

Harrisburg

State/Province

North Carolina

ZIP/Postal Code

28075

Country

United States

Facility Name

Furiex Research Site

City

Hickory

State/Province

North Carolina

ZIP/Postal Code

28601

Country

United States

Facility Name

Furiex Research Site

City

Hickory

State/Province

North Carolina

ZIP/Postal Code

28602

Country

United States

Facility Name

Furiex Research Site

City

High Point

State/Province

North Carolina

ZIP/Postal Code

27262

Country

United States

Facility Name

Furiex Research Site

City

Jacksonville

State/Province

North Carolina

ZIP/Postal Code

28546

Country

United States

Facility Name

Furiex Research Site

City

New Bern

State/Province

North Carolina

ZIP/Postal Code

28562

Country

United States

Facility Name

Furiex Research Site

City

Raleigh

State/Province

North Carolina

ZIP/Postal Code

27609

Country

United States

Facility Name

Furiex Research Site

City

Raleigh

State/Province

North Carolina

ZIP/Postal Code

27612

Country

United States

Facility Name

Furiex Research Site

City

Wilmington

State/Province

North Carolina

ZIP/Postal Code

28401

Country

United States

Facility Name

Furiex Research Site

City

Winston-Salem

State/Province

North Carolina

ZIP/Postal Code

27103-3914

Country

United States

Facility Name

Furiex Research Site

City

Winston-Salem

State/Province

North Carolina

ZIP/Postal Code

27103

Country

United States

Facility Name

Furiex Research Site

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58103

Country

United States

Facility Name

Furiex Research Site

City

Fargo

State/Province

North Dakota

ZIP/Postal Code

58104

Country

United States

Facility Name

Furiex Research Site

City

Akron

State/Province

Ohio

ZIP/Postal Code

44302

Country

United States

Facility Name

Furiex Research Site

City

Beachwood

State/Province

Ohio

ZIP/Postal Code

44122

Country

United States

Facility Name

Furiex Research Site

City

Beavercreek

State/Province

Ohio

ZIP/Postal Code

45432

Country

United States

Facility Name

Furiex Research Site

City

Cincinnati

State/Province

Ohio

ZIP/Postal Code

45229

Country

United States

Facility Name

Furiex Research Site

City

Cleveland

State/Province

Ohio

ZIP/Postal Code

44122

Country

United States

Facility Name

Furiex Research Site

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43214

Country

United States

Facility Name

Furiex Research Site

City

Columbus

State/Province

Ohio

ZIP/Postal Code

43215

Country

United States

Facility Name

Furiex Research Site

City

Dayton

State/Province

Ohio

ZIP/Postal Code

45432

Country

United States

Facility Name

Furiex Research Site

City

Franklin

State/Province

Ohio

ZIP/Postal Code

45005

Country

United States

Facility Name

Furiex Research Site

City

Mentor

State/Province

Ohio

ZIP/Postal Code

44060

Country

United States

Facility Name

Furiex Research Site

City

Miamisburg

State/Province

Ohio

ZIP/Postal Code

45342-3705

Country

United States

Facility Name

Furiex Research Site

City

Springfield

State/Province

Ohio

ZIP/Postal Code

45504

Country

United States

Facility Name

Furiex Research Site

City

Wadsworth

State/Province

Ohio

ZIP/Postal Code

44281

Country

United States

Facility Name

Furiex Research Site

City

Norman

State/Province

Oklahoma

ZIP/Postal Code

73069

Country

United States

Facility Name

Furiex Research Site

City

Norman

State/Province

Oklahoma

ZIP/Postal Code

73071

Country

United States

Facility Name

Furiex Research Site

City

Oklahoma City

State/Province

Oklahoma

ZIP/Postal Code

73104

Country

United States

Facility Name

Furiex Research Site

City

Oklahoma City

State/Province

Oklahoma

ZIP/Postal Code

73112

Country

United States

Facility Name

Furiex Research Site

City

Yukon

State/Province

Oklahoma

ZIP/Postal Code

73099

Country

United States

Facility Name

Furiex Research Site

City

Dingmans Ferry

State/Province

Pennsylvania

ZIP/Postal Code

18328

Country

United States

Facility Name

Furiex Research Site

City

Hermitage

State/Province

Pennsylvania

ZIP/Postal Code

16148

Country

United States

Facility Name

Furiex Research Site

City

Jenkintown

State/Province

Pennsylvania

ZIP/Postal Code

19046

Country

United States

Facility Name

Furiex Research Site

City

Lancaster

State/Province

Pennsylvania

ZIP/Postal Code

17604

Country

United States

Facility Name

Furiex Research Site

City

Lansdale

State/Province

Pennsylvania

ZIP/Postal Code

19446

Country

United States

Facility Name

Furiex Research Site

City

Newton

State/Province

Pennsylvania

ZIP/Postal Code

18940

Country

United States

Facility Name

Furiex Research Site

City

Sayre

State/Province

Pennsylvania

ZIP/Postal Code

18840

Country

United States

Facility Name

Furiex Research Site

City

Uniontown

State/Province

Pennsylvania

ZIP/Postal Code

15401

Country

United States

Facility Name

Furiex Research Site

City

Washington

State/Province

Pennsylvania

ZIP/Postal Code

15301

Country

United States

Facility Name

Furiex Research Site

City

Cumberland

State/Province

Rhode Island

ZIP/Postal Code

02864

Country

United States

Facility Name

Furiex Research Site

City

East Providence

State/Province

Rhode Island

ZIP/Postal Code

02914

Country

United States

Facility Name

Furiex Research Site

City

Warwick

State/Province

Rhode Island

ZIP/Postal Code

02886

Country

United States

Facility Name

Furiex Research Site

City

Anderson

State/Province

South Carolina

ZIP/Postal Code

29621

Country

United States

Facility Name

Furiex Research Site

City

Columbia

State/Province

South Carolina

ZIP/Postal Code

29201

Country

United States

Facility Name

Furiex Research Site

City

Columbia

State/Province

South Carolina

ZIP/Postal Code

29203

Country

United States

Facility Name

Furiex Research Site

City

Greer

State/Province

South Carolina

ZIP/Postal Code

29651

Country

United States

Facility Name

Furiex Research Site

City

Mount Pleasant

State/Province

South Carolina

ZIP/Postal Code

29464

Country

United States

Facility Name

Furiex Research Site

City

Rapid City

State/Province

South Dakota

ZIP/Postal Code

57702

Country

United States

Facility Name

Furiex Research Site

City

Bristol

State/Province

Tennessee

ZIP/Postal Code

37620

Country

United States

Facility Name

Furiex Research Site

City

Chattanooga

State/Province

Tennessee

ZIP/Postal Code

37404

Country

United States

Facility Name

Furiex Research Site

City

Chattanooga

State/Province

Tennessee

ZIP/Postal Code

37421

Country

United States

Facility Name

Furiex Research Site

City

Germantown

State/Province

Tennessee

ZIP/Postal Code

38138

Country

United States

Facility Name

Furiex Research Site

City

Jackson

State/Province

Tennessee

ZIP/Postal Code

38301

Country

United States

Facility Name

Furiex Research Site

City

Johnson City

State/Province

Tennessee

ZIP/Postal Code

37604

Country

United States

Facility Name

Furiex Research Site

City

Kingsport

State/Province

Tennessee

ZIP/Postal Code

37660

Country

United States

Facility Name

Furiex Research Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37203

Country

United States

Facility Name

Furiex Research Site

City

Nashville

State/Province

Tennessee

ZIP/Postal Code

37205

Country

United States

Facility Name

Furiex Research Site

City

Austin

State/Province

Texas

ZIP/Postal Code

78705

Country

United States

Facility Name

Furiex Research Site

City

Bedford

State/Province

Texas

ZIP/Postal Code

76022

Country

United States

Facility Name

Furiex Research Site

City

Colleyville

State/Province

Texas

ZIP/Postal Code

76034

Country

United States

Facility Name

Furiex Research Site

City

El Paso

State/Province

Texas

ZIP/Postal Code

79902

Country

United States

Facility Name

Furiex Research Site

City

Fort Worth

State/Province

Texas

ZIP/Postal Code

76107

Country

United States

Facility Name

Furiex Research Site

City

Fort Worth

State/Province

Texas

ZIP/Postal Code

76108

Country

United States

Facility Name

Furiex Research Site

City

Grand Prairie

State/Province

Texas

ZIP/Postal Code

75052

Country

United States

Facility Name

Furiex Research Site

City

Grapevine

State/Province

Texas

ZIP/Postal Code

76051

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77005

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77022

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77030

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77034

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77074

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77081

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77090

Country

United States

Facility Name

Furiex Research Site

City

Houston

State/Province

Texas

ZIP/Postal Code

77505

Country

United States

Facility Name

Furiex Research Site

City

Hurst

State/Province

Texas

ZIP/Postal Code

76054

Country

United States

Facility Name

Furiex Research Site

City

Irving

State/Province

Texas

ZIP/Postal Code

75061

Country

United States

Facility Name

Furiex Research Site

City

Lake Jackson

State/Province

Texas

ZIP/Postal Code

77566

Country

United States

Facility Name

Furiex Research Site

City

Marshall

State/Province

Texas

ZIP/Postal Code

75670

Country

United States

Facility Name

Furiex Research Site

City

North Richland Hills

State/Province

Texas

ZIP/Postal Code

76180

Country

United States

Facility Name

Furiex Research Site

City

Odessa

State/Province

Texas

ZIP/Postal Code

79761

Country

United States

Facility Name

Furiex Research Site

City

Plano

State/Province

Texas

ZIP/Postal Code

75074

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78209

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78212

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78215

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78229

Country

United States

Facility Name

Furiex Research Site

City

San Antonio

State/Province

Texas

ZIP/Postal Code

78258

Country

United States

Facility Name

Furiex Research Site

City

Sugar Land

State/Province

Texas

ZIP/Postal Code

77478

Country

United States

Facility Name

Furiex Research Site

City

Sugar Land

State/Province

Texas

ZIP/Postal Code

77479

Country

United States

Facility Name

Furiex Research Site

City

Webster

State/Province

Texas

ZIP/Postal Code

77598

Country

United States

Facility Name

Furiex Research Site

City

Logan

State/Province

Utah

ZIP/Postal Code

84341

Country

United States

Facility Name

Furiex Research Site

City

Ogden

State/Province

Utah

ZIP/Postal Code

84405

Country

United States

Facility Name

Furiex Research Site

City

Salt Lake City

State/Province

Utah

ZIP/Postal Code

84109

Country

United States

Facility Name

Furiex Research Site

City

Salt Lake City

State/Province

Utah

ZIP/Postal Code

84121

Country

United States

Facility Name

Furiex Research Site

City

South Jordan

State/Province

Utah

ZIP/Postal Code

84095

Country

United States

Facility Name

Furiex Research Site

City

West Jordan

State/Province

Utah

ZIP/Postal Code

84088

Country

United States

Facility Name

Furiex Research Site

City

West Valley City

State/Province

Utah

ZIP/Postal Code

84120

Country

United States

Facility Name

Furiex Research Site

City

Alexandria

State/Province

Virginia

ZIP/Postal Code

22304

Country

United States

Facility Name

Furiex Research Site

City

Chesapeake

State/Province

Virginia

ZIP/Postal Code

23320

Country

United States

Facility Name

Furiex Research Site

City

Christiansburg

State/Province

Virginia

ZIP/Postal Code

24073

Country

United States

Facility Name

Furiex Research Site

City

Danville

State/Province

Virginia

ZIP/Postal Code

24541

Country

United States

Facility Name

Furiex Research Site

City

Fairfax

State/Province

Virginia

ZIP/Postal Code

22031

Country

United States

Facility Name

Furiex Research Site

City

Virginia Beach

State/Province

Virginia

ZIP/Postal Code

23455

Country

United States

Facility Name

Furiex Research Site

City

Mill Creek

State/Province

Washington

ZIP/Postal Code

98012-6316

Country

United States

Facility Name

Furiex Research Site

City

Madison

State/Province

Wisconsin

ZIP/Postal Code

53715

Country

United States

Facility Name

Furiex Research Site

City

Milwaukee

State/Province

Wisconsin

ZIP/Postal Code

53226

Country

United States

12. IPD Sharing Statement

Citations:

PubMed Identifier

28167156

Citation

Fant RV, Henningfield JE, Cash BD, Dove LS, Covington PS. Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea. Clin Gastroenterol Hepatol. 2017 Jul;15(7):1021-1029.e6. doi: 10.1016/j.cgh.2017.01.026. Epub 2017 Feb 3.

Results Reference

derived

PubMed Identifier

24813429

Citation

Andrae DA, Covington PS, Patrick DL. Item-level assessment of the irritable bowel syndrome quality of life questionnaire in patients with diarrheal irritable bowel syndrome. Clin Ther. 2014 May;36(5):663-79. doi: 10.1016/j.clinthera.2014.04.009. Epub 2014 May 9.

Results Reference

derived

PubMed Identifier

23583433

Citation

Dove LS, Lembo A, Randall CW, Fogel R, Andrae D, Davenport JM, McIntyre G, Almenoff JS, Covington PS. Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study. Gastroenterology. 2013 Aug;145(2):329-38.e1. doi: 10.1053/j.gastro.2013.04.006. Epub 2013 Apr 9.

Results Reference

derived

Learn more about this trial

Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea

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Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea

Irritable Bowel Syndrome

About this trial

Eligibility Criteria

Sites / Locations

Arms of the Study

Arm 1

Arm 2

Arm 3

Arm 4

Arm 5

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

1. Study Identification

2. Study Status

3. Sponsor/Collaborators

4. Oversight

5. Study Description

6. Conditions and Keywords

7. Study Design

8. Arms, Groups, and Interventions

10. Eligibility

12. IPD Sharing Statement

Learn more about this trial