Emotion Assessment to Study Consciousness in Awakening Patients (EmotiCones)
Persistent Vegetative State
About this trial
This is an interventional diagnostic trial for Persistent Vegetative State focused on measuring Persistent Vegetative State, minimally conscious state, Emotions, Awareness, electrodermal activity, Electroencephalography
Eligibility Criteria
Inclusion Criteria:
For Patients :
- age between 18 and 80
- acquired brain lesion (brain injury, stroke, anoxia) with a delay since the insult superior to 1 month
- level of consciousness assessed with the coma recovery scale revised (CRS-R)
- patient with health insurance
- informed consent signed by the patients or his representative
For Healthy participants:
- age between 18 and 80
- participant able to understand instructions and normal hearing
- patient with health insurance
- informed consent signed
Exclusion Criteria:
For Patients :
- non controlled epilepsy
- dysautonomic crisis
- unstable medical state
- pregnancy or breath feeding for women
- Persons under guardianship, curatorship
For Healthy participants:
- neurological disorder
- pregnancy or breath feeding for women
- Persons under guardianship, curatorship or any other administrative or judicial measure of deprivation of rights or liberty
Sites / Locations
- Hospices Civils de LyonRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Experimental
Experimental
Experimental
Vegetative State
Minimally Conscious State
Acquired Brain damaged patients without DOC
Healthy subjects
For patients in vegetative state (n=15), three experiments will be performed during 2 days in order to assess emotions and consciousness with physiological variables and electroencephalography.
For patients in minimally conscious state (n = 15), three experiments will be performed during 2 days in order to assess emotions and consciousness with physiological variables and electroencephalography.
Acquired Brain damaged patients without disorder of consciousness (patients without DOC) For patients with acquired brain damage without disorder of consciousness (n=15), three experiments will be performed during 2 days in order to assess emotions and consciousness with physiological variables and electroencephalography
For healthy subjects (n=15), three experiments will be performed during 2 days in order to assess emotions and consciousness with physiological variables and electroencephalography.