Endobronchial Ultrasound vs Mediastinoscopy in NSCLC
Non-small Cell Lung Cancer
About this trial
This is an interventional diagnostic trial for Non-small Cell Lung Cancer focused on measuring Non-small cell lung cancer, NSCLC, EBUS, Endobronchial ultrasound, mediastinoscopy
Eligibility Criteria
Inclusion Criteria:
A) Age 18 years or older B) Patients with confirmed or suspected non-small cell lung cancer who require a mediastinoscopy as part of their staging investigations of the mediastinum to determine suitability for lung cancer resection will be considered for the trial.
C) Patients with undiagnosed enlarged lymph nodes in the mediastinum suspicious for lung cancer in which a tissue diagnosis is required.
Exclusion Criteria:
A) Patients who are deemed on clinical grounds not to be medically fit for a bronchoscopy or a mediastinoscopy or who are not suitable for definitive surgical resection by thoracotomy will be excluded.
B) Patients who have verified stage IV disease or who are not appropriate for lung cancer resection by virtue of direct invasion of mediastinal structures or large parts of the chest wall.
C) Known small cell lung cancer. D) Patients where there is a high clinical suspicion of lymphoma. E) Inability to give informed consent.
Sites / Locations
- University Health Network (Toronto General Hospital)
Arms of the Study
Arm 1
Experimental
Endobronchial ultrasound