Endoscopic Ultrasound Determines Disease Activity in Crohn's Disease And Ulcerative Colitis (EUSIBD)
Crohn Disease, Ulcerative Colitis
About this trial
This is an interventional diagnostic trial for Crohn Disease focused on measuring crohn's disease, ulcerative colitis, endoscopic ultrasound, inflammatory bowel disease
Eligibility Criteria
Inclusion Criteria:
- Adults patients ≥ 18 years of age with CD with at least colonic involvement, UC, or non-IBD controls who have been referred for colonoscopy for clinical reasons. The clinical reasons may include colorectal cancer screening, surveillance, diagnostic for CD or UC flare, or gastrointestinal symptoms.
Exclusion Criteria:
- Pregnant patients.
- Patients with known current colorectal cancer, infectious colitis, diverticulitis, or microscopic colitis.
- Patients who have undergone surgery involving the cecum or rectum.
Sites / Locations
- Carilion ClinicRecruiting
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Experimental
Experimental
Crohn's Disease
Ulcerative Colitis
Non-IBD Controls
20 patients with Crohn's disease with at least colonic involvement will undergo endoscopic ultrasound assessment of the thickness of wall layers (mucosa, submucosa, muscularis propria, total wall) at the rectum and cecum region during their standard-of-care colonoscopy.
20 patients with ulcerative colitis will undergo endoscopic ultrasound assessment of the thickness of wall layers (mucosa, submucosa, muscularis propria, total wall) at the rectum and cecum region during their standard-of-care colonoscopy.
20 patients without inflammatory bowel disease (controls) will undergo endoscopic ultrasound assessment of the thickness of wall layers (mucosa, submucosa, muscularis propria, total wall) at the rectum and cecum region during their standard-of-care colonoscopy.