Enhanced Recovery After Surgery Program for Gastric Cancer: a Multi-center Study (ERASG1)
Gastric Cancer
About this trial
This is an interventional treatment trial for Gastric Cancer focused on measuring enhanced recovery after surgery, gastric cancer
Eligibility Criteria
Inclusion Criteria:
- Requirements of informed consent and assent of participant, parent or legal guardian as applicable
- Patients with gastric cancer scheduled for radical gastrectomy and between the age of 18 and 75 years old without considering sex
- ASA physical status I-III
- Participants can follow the drug doses and visit plan
Exclusion Criteria:
- Patients certified by a doctor that doesn't fit to participate in this study.
- Patients with ischemic heart disease, cerebrovascular disease and peripheral vascular disease, or their cardiac function > II (NYHA) patients, patients received CABG recently, and patients with severe hypertension (systolic pressure≥180mmHg or diastolic pressure≥110mmHg).
- Patients with gastric cancer with distant metastasis.
- Patients with severe infection, respiratory dysfunction, coagulation disorders, severe liver and renal dysfunction (Child - Pugh≥ 10; creatinine clearance < 25 ml/min).
- Patients allergic to common drugs, such as opioids, non-steroidal drugs, cephalosporins, etc.
- Patients with operations of gastrointestinal cancer and complicated abdominal operations.
- Patients complicated by gastric cancer with complications such as hemorrhage, perforation, obstruction.
- Patients with dyscrasia and severe malnutrition (albumin≤30g/L, weight loss in half a year>10%, SGA classification C, BMI<18, Hb<70g/L).
- Patients with metabolic complications caused by diabetes.
- Patients can't finish enhanced recovery after surgery programs and have contraindications of enhanced recovery after surgery.
- Pregnancy and lactation women, or have a pregnancy plan within a month after the test of the subjects (also including male participants).
- Patients participated other subjects 3 months before this subject.
- Sponsors or researchers directly involved in the testing or their family members.
Sites / Locations
- The First People's Hospital of ChangzhouRecruiting
- Changzhou Second People's Hospital Affiliated to Nanjing Medical UniversityRecruiting
- The First People's Hospital of Lianyungang CityRecruiting
- The Second People's Hospital of Lianyungang CityRecruiting
- Jiangsu Cancer HospitalRecruiting
- Nanjing First HospitalRecruiting
- Jinling Hospital, Medical School of Nanjing UniversityRecruiting
- Zhongda Hospital, Southeast UniversityRecruiting
- the Second Affiliated Hospital of Nanjing Medical UniversityRecruiting
- the First Affiliated Hospital of Nanjing Medical UniversityRecruiting
- Suqian People's Hospital, Nanjing Drum Tower HospitalRecruiting
- Suzhou Municipal HospitalRecruiting
- The Second Affiliated Hospital of Soochow UniversityRecruiting
- The First Affiliated Hospital of Soochow UniversityRecruiting
- The First People's Hospital of TaicangRecruiting
- Zhangjiagang First People's HospitalRecruiting
- the Taizhou People's HospitalRecruiting
- The 101 Hospital of the Chinese People's Liberation ArmyRecruiting
- Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi CityRecruiting
- Xuzhou Central HospitalRecruiting
- Northern Jiangsu People's HospitalRecruiting
- Affiliated Hospital of Jiangsu UniversityRecruiting
- Affiliated People's Hospital of Jiangsu UniversityRecruiting
Arms of the Study
Arm 1
Experimental
enhanced recovery after surgery
enhanced recovery after surgery includes: Multimodal analgesia Early oral intake A: Drink water after anesthetic awareness. B: Recover semi-liquid diet Management of nasogastric tube and catheter A: Not indwell nasogastric tube conventionally B: Remove catheter early Early activity Perioperative controlled infusion A: Load carbohydrate preoperatively B: No preoperative bowel preparation C: Fast six hours before surgery, no drink two hours before surgery D: Intraoperative liquid management: 3-6ml/kg/h, determined by anesthetists E: Stop intravenous infusion upon 2000-2500ml water and semiliquid diet being taken