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Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game

Primary Purpose

Neurodevelopmental Disorders

Status
Active
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Game
Sponsored by
Yale University
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Neurodevelopmental Disorders

Eligibility Criteria

undefined - undefined (Child, Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Able to participate in an eye-tracking experiment
  • Able to participate in an EEG experiment

Exclusion Criteria:

  • Sensory or physical impairment that would preclude completion of protocol
  • Participants taking prescription medications that may affect cognitive processes
  • Participants reporting significant head trauma or history of seizures

Sites / Locations

  • Yale Child Study Center

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Game

Arm Description

Participants will play a video game directing their gaze to on-screen targets.

Outcomes

Primary Outcome Measures

EEG brain response to targets

Secondary Outcome Measures

Visual attention to targets as measured by eye-tracking
Social Responsiveness Scale, Second Edition
Autism Diagnostic Observation Schedule
Differential Abilities Scale
Vineland Adaptive Behavior Scales, Second Edition
Social Anxiety Scale for Children, Revised

Full Information

First Posted
April 5, 2014
Last Updated
April 6, 2023
Sponsor
Yale University
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1. Study Identification

Unique Protocol Identification Number
NCT02118649
Brief Title
Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game
Study Type
Interventional

2. Study Status

Record Verification Date
April 2023
Overall Recruitment Status
Active, not recruiting
Study Start Date
April 2014 (undefined)
Primary Completion Date
April 2024 (Anticipated)
Study Completion Date
April 2024 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Yale University

4. Oversight

Data Monitoring Committee
No

5. Study Description

Brief Summary
Participants will play a computer game that is controlled by their gaze patterns and designed to direct attention their attention to specific on-screen targets. Visual attention to targets will be rewarded. Both visual behavior and brain response will be recorded during game play. It is hypothesized that that, over the course of the game, relative to baseline, participants will show (a) increased looking to targets, (b) decreased response time to targets, and (c) enhanced, more efficient neural response to visual cues. It is hypothesized that clinical variability will associate with visual attention and brain response.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Neurodevelopmental Disorders

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
100 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Game
Arm Type
Experimental
Arm Description
Participants will play a video game directing their gaze to on-screen targets.
Intervention Type
Behavioral
Intervention Name(s)
Game
Primary Outcome Measure Information:
Title
EEG brain response to targets
Time Frame
Measures will be recorded for the duration of their visit, an expected average of 3 hours.
Secondary Outcome Measure Information:
Title
Visual attention to targets as measured by eye-tracking
Time Frame
Measures will be recorded for the duration of their visit, an expected average of 3 hours.
Title
Social Responsiveness Scale, Second Edition
Time Frame
Measures will be collected during visit, an expected average of 3 hours.
Title
Autism Diagnostic Observation Schedule
Time Frame
Measures will be collected during visit, an expected average of 3 hours.
Title
Differential Abilities Scale
Time Frame
Measures will be collected during visit, an expected average of 3 hours.
Title
Vineland Adaptive Behavior Scales, Second Edition
Time Frame
Measures will be collected during visit, an expected average of 3 hours.
Title
Social Anxiety Scale for Children, Revised
Time Frame
Measures will be collected during visit, an expected average of 3 hours.

10. Eligibility

Sex
All
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria: Able to participate in an eye-tracking experiment Able to participate in an EEG experiment Exclusion Criteria: Sensory or physical impairment that would preclude completion of protocol Participants taking prescription medications that may affect cognitive processes Participants reporting significant head trauma or history of seizures
Facility Information:
Facility Name
Yale Child Study Center
City
New Haven
State/Province
Connecticut
ZIP/Postal Code
06520
Country
United States

12. IPD Sharing Statement

Citations:
PubMed Identifier
5970485
Citation
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Citation
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PubMed Identifier
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Citation
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PubMed Identifier
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Citation
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PubMed Identifier
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Citation
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Results Reference
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PubMed Identifier
11261466
Citation
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PubMed Identifier
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Citation
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PubMed Identifier
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Citation
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Citation
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Citation
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Results Reference
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Citation
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Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game

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