Establishing the Physiology of Syringomyelia
Arnold Chiari Deformity, Hydrocephalus, Syringomyelia
About this trial
This is an observational trial for Arnold Chiari Deformity focused on measuring Syringomyelia, Chiari Malformation, Magnetic Resonance Imaging, Intraoperative Ultrasonography, Hydrocephalus, Spinal Cord, Ventriculostomy, Lumbar Puncture, Pressure Measurement
Eligibility Criteria
INCLUSION CRITERIA: To be eligible to participate in this research study, the subject must: Be 18 years of age or older. Have syringomyelia. Have a lesion that narrows the space for spinal fluid at the base of the skull or neck. Prior surgery for syringomyelia does not result in exclusion from the study if there is radiographic evidence of a syrinx and there is evidence of neurological deterioration related to the syrinx. Be able to give informed consent. EXCLUSION CRITERIA: The subject will not be eligible to participate in this research study if the subject: Is pregnant (because X-rays might injure a fetus). Cannot have an MRI scan as determined by the radiologist. Has a problem with bleeding that cannot be corrected. Is unable to understand the risks of the testing and surgical therapy. Has a blood test for HIV (the virus that causes AIDS) that is positive, because a positive HIV test would increase the risk of infection from research testing.
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike