Back to resultsEvaluating Patients With Abnormal Levels of Gastric Acid
Primary Purpose
Achlorhydria, Gastrinoma, Zollinger Ellison Syndrome
Status
Completed
Phase
Locations
United States
Study Type
Observational
Intervention
Sponsored by
About this trial
This is an observational trial for Achlorhydria focused on measuring Stomach, Hypersecretion, Hyposecretion, Gastrinoma, Zollinger-Ellison Syndrome
Eligibility Criteria
Eligibility criteria not identified in the protocol.
Sites / Locations
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
NCT ID
NCT00001240
First Posted
November 3, 1999
Last Updated
March 4, 2008
Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
1. Study Identification
Unique Protocol Identification Number
NCT00001240
Brief Title
Evaluating Patients With Abnormal Levels of Gastric Acid
Official Title
Diagnostic Evaluation of Patients With Suspected Abnormalities of Gastric Secretion
Study Type
Observational
2. Study Status
Record Verification Date
January 2004
Overall Recruitment Status
Completed
Study Start Date
January 1989 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
January 2004 (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
4. Oversight
5. Study Description
Brief Summary
This study is used by the Digestive Diseases Branch to evaluate patients with suspected abnormalities in the secretion of gastric acid. The level of gastric acid is measured by analyzing the gastric juices of each individual patient. The gastric acid sample is obtained by a procedure known as nasogastric suctioning, where a thin plastic tube is passed from the nose to the stomach.
Depending on the patient's present condition further diagnostic testing may be required to achieve a diagnosis.
Detailed Description
This study is an omnibus protocol used by the Digestive Diseases Branch to evaluate patients with suspected abnormalities of gastric acid secretion. Gastric acid secretion is measured by means of analysis of gastric juices obtained by nasogastric suction. Other clinically indicated diagnostic procedures are performed depending on the patient's clinical state in order to reach a diagnosis.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Achlorhydria, Gastrinoma, Zollinger Ellison Syndrome
Keywords
Stomach, Hypersecretion, Hyposecretion, Gastrinoma, Zollinger-Ellison Syndrome
7. Study Design
10. Eligibility
Sex
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Eligibility criteria not identified in the protocol.
Facility Information:
Facility Name
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
City
Bethesda
State/Province
Maryland
ZIP/Postal Code
20892
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
3972233
Citation
McArthur KE, Collen MJ, Maton PN, Cherner JA, Howard JM, Ciarleglio CA, Cornelius MJ, Jensen RT, Gardner JD. Omeprazole: effective, convenient therapy for Zollinger-Ellison syndrome. Gastroenterology. 1985 Apr;88(4):939-44. doi: 10.1016/s0016-5085(85)80011-1.
Results Reference
background
PubMed Identifier
2857672
Citation
Howard JM, Chremos AN, Collen MJ, McArthur KE, Cherner JA, Maton PN, Ciarleglio CA, Cornelius MJ, Gardner JD, Jensen RT. Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome. Gastroenterology. 1985 Apr;88(4):1026-33. doi: 10.1016/s0016-5085(85)80024-x.
Results Reference
background
PubMed Identifier
2877575
Citation
Vinayek R, Howard JM, Maton PN, Wank SA, Slaff JI, Gardner JD, Jensen RT. Famotidine in the therapy of gastric hypersecretory states. Am J Med. 1986 Oct 24;81(4B):49-59. doi: 10.1016/0002-9343(86)90600-5.
Results Reference
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Evaluating Patients With Abnormal Levels of Gastric Acid
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