Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism
Autism, Pervasive Developmental Disorder
About this trial
This is an interventional treatment trial for Autism
Eligibility Criteria
Inclusion Criteria: Ages 3-8 years Diagnosis of autism spectrum disorder Serum copper/zinc ratio greater than 2.0 or as determined in phase 1 of the study Exclusion Criteria: Known chromosomal disorder or neurological disorders other than autism
Sites / Locations
- Penn State Children's Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Oral zinc and vitamin C supplementation
Oral Placebo
Participant will receive oral zinc and vitamin C supplementation based on the child's weight. Blood levels of zinc, copper, liver and renal function as well as blood counts will be measured. Copper to zinc ratio will be calculated at 6 and 16 weeks
Participant will receive placebo liquid with volume based on child's weight to match the amount given to participants in the experimental group.