Evaluation of Effectiveness and Safety of Paliperidone ER (Extended-release) Compared With Quetiapine in Patients With Schizophrenia
Schizophrenia
About this trial
This is an interventional treatment trial for Schizophrenia focused on measuring Schizophrenia, Antipsychotic, paliperidone, quetiapine, Seroquel, placebo
Eligibility Criteria
Inclusion Criteria: Diagnostic and Statistical Manual - Fourth Edition (DSM-IV) diagnosis of schizophrenia (paranoid, disorganized or undifferentiated type) score of >=4 on at least two of a subset of selected PANSS items and a total score on these five items of >=17 score of >=5 on the CGI-S (clinical global impression - severity) body weight of at least 60kg and willing to be hospitalized for 9 days initially Exclusion Criteria: A primary active mental illness diagnosis other than schizophrenia subjects whose psychotic symptoms can be explained by substance intake or medical illness pregnancy, breast-feeding, or planning to become pregnant a history of treatment resistance (defined by failure to respond to 2 adequate trials of different antipsychotic medications or clozapine given at adequate dose for sufficient time) unstable or significant medical illness that would increase risk of taking study medication or would confuse the interpretation of the study