Evaluation of Intensive Language Therapy (EILT)
Parkinson's Disease
About this trial
This is an interventional treatment trial for Parkinson's Disease focused on measuring Parkinson's Disease, Word Retrieval, Apraxia Symptoms, Dysarthria
Eligibility Criteria
Inclusion Criteria for all groups:
- The patient is able to cooperate
- The patient has the mental competence to provide informed consent to participate in the study
- The patient speaks and understands German
Specific Inclusion Criteria for the DBS Group
- Fulfilling the above stated inclusion criteria as stated in a, b and c above
- The patient is responsive to Levodopa (L-DOPA)
- Having received or being scheduled for DBS
Exclusion Criteria:
- Severe psychiatric disease difficult to treat (compulsive disorder, depression, mania, psychosis, anxiety as outlined in International Classification of Diseases (ICD-10) (WHO 2015, current version).
- Patient with dementia (DMS-V, Mini-Mental-Status-Test (MMS) <24, Montreal Cognitive Assessment (MoCa) <21)
- Secondary Parkinsonism
- Age ≤18 years
- Pregnancy (early onset)
- Presence of a known disease other than PD that shortens the life expectancy
- Mental incompetence to provide informed consent to participate in the study
- Previous intracranial surgery
- Epilepsy
- Contraindications for DBS seen in MRI-scan (malignant tumour, severe microvascular disease)
- Insufficient skills of German language for participating in neuropsychological evaluations
- Sensory problems, severe enough to significantly interfere with neuropsychological assessment
- Alcohol and/or drug addiction
Sites / Locations
- University Hospital Basel
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Active Comparator
No Intervention
No Intervention
Specific SL-therapy for PD (with and without DBS)
rBMT for PD (with and without DBS)
PD (with and without DBS); no therapy
Healthy Controls; no therapy
Rhythmic specific, intensive and high-frequency SL-therapy. Approx. 45 Min. per session, 3 times per week for 4 weeks
Rhythmic Balance-Movement Training (rBMT); approx. 30-45 Minutes per session, 3 times per week for 4 weeks
No further recruiting necessary, as data is already at hand via previous research projects.
No further recruiting necessary, as data is already at hand via previous research projects.