Evaluation of New Test Method to Measure Kidney Function
Kidney Disease
About this trial
This is an observational trial for Kidney Disease focused on measuring Renal Function, Iothalamate
Eligibility Criteria
INCLUSION CRITERIA: Both male and female subjects will be recruited without regard to race or ethnic origin. Suspected renal dysfunction based upon: Acute renal failure with elevated serum creatinine (at least 50% increase within 24 hours preceding enrollment) without stabilization or recovery, despite optimization of hemodynamic fluid status and correction of any known pharmacologic, pre-renal, or post-renal etiologic factors, or Congestive heart failure by clinical criteria (rales, S3, pedal edema on clinical exam), or Edema or ascites (by clinical exam), or Sepsis or septic physiology (shock or hyperdynamic circulation, suspected sepsis), or Chronic Renal Failure (creatinine greater than 1.3). Patients older than 18 years old who provide their own informed consent. Patients younger than 18 but at least 6 years old whose parent or legal guardian can provide informed consent. EXCLUSION CRITERIA: Inability to cooperate with the study. Known allergy to iothalamate or other iodine containing compounds. Urinary tract obstruction. Pregnant women or lactating mothers. Patients in whom vascular access cannot be secured.
Sites / Locations
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)