Evaluation of the Effectiveness of a Protocol for the Management of Female Functional Urinary Signs (PharmaCyst')
Cystitis Acute
About this trial
This is an interventional other trial for Cystitis Acute
Eligibility Criteria
Inclusion Criteria:
- Female
- Age ≥ 18 and <65 years
Patient with less than 3 days of simple urinary tract infection symptoms:
- Burning, pain on urination
- Dysuria
- Pollakiuria
- Urinary urgency
- Patient affiliated or beneficiary of a social insurance
- Patient having signed an informed consent.
Exclusion Criteria:
- More than 3 cystitis in the last 12 months;
- Last cystitis less than 15 days old;
- Presence of fever;
- Presence of back pain;
- Presence of a functional or organic anomaly of the urinary tract (bladder residue, vesico-ureteral reflux, lithiasis, tumor);
- Pruritus or vaginal discharge;
- Vomiting, diarrhea, diffuse abdominal pain;
- Risk factors for C3G-resistant enterobacteria infection (grade B):
- Exposure to an antibiotic (amoxicillin-clavulanic acid, C2G, C3G, fluoroquinolones) within the previous 3 months;
- A nosocomial or healthcare-associated infection;
- A history of colonization or infection with C3G-resistant enterobacteria within the last 3 months;
- A trip to a foreign country within the last 3 months in known geographical areas at risk (in particular the Indian subcontinent, South-East Asia, the Middle East and North Africa, the Mediterranean basin);
- Hospitalization within 3 months;
- Hospitalization within 6 months for UTI;
- Known severe renal insufficiency (creatinine clearance < 30 mL/min);
- Severe immunosuppression or immunosuppressive treatments;
- Contraindications to drugs planned for experimental management (pivmecillinam and fosfomycin) or combination of drugs not recommended;
- Pregnant women (confirmed or suspected pregnancy), breastfeeding women or women in labour;
- Person deprived of liberty by judicial or administrative decision;
- Person under forced psychiatric care;
- Person admitted to a health or social institution for purposes other than research;
- Person subject to a legal protection measure; A- person who is unable to give consent.
Sites / Locations
- Pharmacie du Pays De RetzRecruiting
- Pharmacie du Clocher
- Pharmacie de Brûlon
- Pharmacie du Centre
- Pharmacie Degueille
- Pharmacie Nicolleau-Dilé
- Pharmacie des HallesRecruiting
- Pharmacie Principale Harel
- Pharmacie de la PlaceRecruiting
- Pharmacie de Gazonfier
- Pharmacie de la Pointe
- Pharmacie du Centre
- Pharmacie Leeuws-Guilloton
- Pharmacie de la Presqu'île
- Pharmacie du Louet
- Pharmacie Flotté
- Pharmacie des Arcades
- Pharmacie de la Place
- Pharmacie DerocheRecruiting
- Pharmacie des Glycines
- Pharmacie LlacunaRecruiting
- Pharmacie du Chemin Vert
- Pharmacie des Rives du Loir
- Pharmacie de la Source
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Management with the protocol
Standard care
Patients who participate in the study in the experimental arm benefit from an adapted management, which falls under the application of the national cooperation protocol. This management may lead to the dispensing of an antibiotic by the pharmacist himself.
Patients participating in the study in the control arm will benefit from a management comparable to the current one. In addition to a reminder of the hygienic and dietary rules by the pharmacist, the patient may be offered a drug indicated for improving urinary comfort. The pharmacist should also remind the patient that she can consult a doctor, especially in case of non relief or aggravation of symptoms.