Evaluation of the Efficacy of Different Strategies to Treat Anemia in Mexican Children
Primary Purpose
Anemia
Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Iron
Multiple micronutrients supplement
micronutrient fortified porridge powder
Iron and ascorbic acid fortified water
Iron plus folic acid supplement
Sponsored by

About this trial
This is an interventional treatment trial for Anemia focused on measuring Anemia, Iron, Children, Micronutrients
Eligibility Criteria
Inclusion Criteria:
- Hemoglobin less than 11.7g/dL and above 7.0g/dL
Exclusion Criteria:
- Breastfeeding
- Chronic gastroenteritis
- Any other severe illness
Sites / Locations
Arms of the Study
Arm 1
Arm Type
Experimental
Arm Label
Anemic children
Arm Description
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
NCT ID
NCT00822380
First Posted
January 13, 2009
Last Updated
January 13, 2009
Sponsor
Universidad Autonoma de Queretaro
Collaborators
Procter and Gamble
1. Study Identification
Unique Protocol Identification Number
NCT00822380
Brief Title
Evaluation of the Efficacy of Different Strategies to Treat Anemia in Mexican Children
Official Title
Evaluation of the Efficacy of Different Strategies to Treat Anemia in Mexican Children: A Randomized Clinical Trial
Study Type
Interventional
2. Study Status
Record Verification Date
January 2009
Overall Recruitment Status
Completed
Study Start Date
March 2003 (undefined)
Primary Completion Date
November 2003 (Actual)
Study Completion Date
November 2004 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
Universidad Autonoma de Queretaro
Collaborators
Procter and Gamble
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Anemia continues to be a major public health problem in many regions of the world and it is still not clear which strategy is more effective in children population in terms of adherence and efficacy. The objective was to evaluate the efficacy and acceptance of several strategies that have been recently recommended to treat anemia on anemic children (6 to 43 mo):Iron supplement, iron+folic acid supplement, a multiple micronutrients supplement a micronutrient fortified complementary food in the form of porridge powder or zinc+iron+ascorbic acid fortified water.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Anemia
Keywords
Anemia, Iron, Children, Micronutrients
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Participant
Allocation
Randomized
Enrollment
680 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Anemic children
Arm Type
Experimental
Intervention Type
Dietary Supplement
Intervention Name(s)
Iron
Intervention Description
Daily 20mg of ferrous sulfate in liquid solution during 4 months
Intervention Type
Dietary Supplement
Intervention Name(s)
Multiple micronutrients supplement
Intervention Description
Daily supplement with 10mg of iron plus several micronutrients following a formula designed to treat anemia in indigenous population in Mexico. During 4 months.
Intervention Type
Dietary Supplement
Intervention Name(s)
micronutrient fortified porridge powder
Intervention Description
Daily powdered complementary food designed for a national program in Mexico with 10mg of iron plus several micronutrients during 4 months
Intervention Type
Dietary Supplement
Intervention Name(s)
Iron and ascorbic acid fortified water
Intervention Description
A drink water product fortified with 6.7 mg ofiron, zinc and ascorbic acid. This product was asked to be used for drinking and for cooking for the child during 4 months.
Intervention Type
Dietary Supplement
Intervention Name(s)
Iron plus folic acid supplement
Intervention Description
Daily liquid solution following the daily iron (12.5mg)and folic acid recommendation of UNICEF to treat anemia during 4 months
10. Eligibility
Sex
All
Minimum Age & Unit of Time
6 Months
Maximum Age & Unit of Time
42 Months
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Hemoglobin less than 11.7g/dL and above 7.0g/dL
Exclusion Criteria:
Breastfeeding
Chronic gastroenteritis
Any other severe illness
12. IPD Sharing Statement
Citations:
PubMed Identifier
20863398
Citation
Rosado JL, Gonzalez KE, Caamano Mdel C, Garcia OP, Preciado R, Odio M. Efficacy of different strategies to treat anemia in children: a randomized clinical trial. Nutr J. 2010 Sep 23;9:40. doi: 10.1186/1475-2891-9-40.
Results Reference
derived
Learn more about this trial
Evaluation of the Efficacy of Different Strategies to Treat Anemia in Mexican Children
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