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Evaluation of the Results of Closed Kinetic Chain Exercises in Patellofemoral Pain Syndrome

Primary Purpose

Exercise Training

Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Non-selective closed kinetic chain exercises (NSKCE) and selective closed kinetic chain exercises (SCKCE)
Sponsored by
Taksim Egitim ve Arastirma Hastanesi
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Exercise Training focused on measuring Elastography, exercises, non-selective, pain, patellofemoral

Eligibility Criteria

17 Years - 60 Years (Child, Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria:

  • Having peripatellar/retropatellar pain while sitting,going up and down the stairs
  • Walking for a long time, crouching down, running, and kneeling down
  • Having a VAS score of ≥3 during the evaluation and not developing these symptoms on a traumatic basis

Exclusion Criteria:

  • Tendinitis
  • Osgood-Schlatter Syndrome
  • Traumatic hip or knee injuries
  • Osteoarthritis
  • Plica syndrome
  • Sinding-Larsen-Johansson syndrome
  • Ligamentous instability
  • Spinal pain
  • Chondral lesion
  • Patellar tendon pathology
  • Distraction apophysitis of knee circumference

Sites / Locations

    Arms of the Study

    Arm 1

    Arm 2

    Arm 3

    Arm Type

    Experimental

    Experimental

    Other

    Arm Label

    Diseased side of the patellofemoral pain syndrome (PFPS) group (40 knees)

    Healthy side of the patellofemoral pain syndrome (PFPS) group (40 knees)

    Both side of the healthy control group (80 knees)

    Arm Description

    Non-selective close kinetic chain exercises and selective close kinetic chain exercises were applied for 6 weeks in diseased side of the PFPS group. Thigh circumference measurement was performed 5-10 cm above the upper pole of the patella. In addition, evaluation was made with visual analog score (VAS) and Lysholm Knee score (LKS). Vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of the participants were measured with Shear Wave Elastography 1 day before the therapy and 6 weeks after therapy in hospital.

    Non-selective close kinetic chain exercises and selective close kinetic chain exercises were applied for 6 weeks in healthy side of the PFPS group. Thigh circumference measurement was performed 5-10 cm above the upper pole of the patella. In addition, evaluation was made with visual analog score (VAS) and Lysholm Knee score (LKS). Vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of the participants were measured with Shear Wave Elastography 1 day before the therapy and 6 weeks after therapy in hospital.

    Non-selective close kinetic chain exercises and selective close kinetic chain exercises were applied for 6 weeks in side of the both side of the healthy control group. Thigh circumference measurement was performed 5-10 cm above the upper pole of the patella. In addition, evaluation was made with visual analog score (VAS) and Lysholm Knee score (LKS). Vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of the participants were measured with Shear Wave Elastography 1 day before the therapy and 6 weeks after therapy in hospital.

    Outcomes

    Primary Outcome Measures

    Shear Wave Elastography
    Measurement of muscle strength before exercises
    Shear Wave Elastography
    Measurement of muscle strength after exercises

    Secondary Outcome Measures

    Full Information

    First Posted
    June 7, 2022
    Last Updated
    June 16, 2022
    Sponsor
    Taksim Egitim ve Arastirma Hastanesi
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    1. Study Identification

    Unique Protocol Identification Number
    NCT05427357
    Brief Title
    Evaluation of the Results of Closed Kinetic Chain Exercises in Patellofemoral Pain Syndrome
    Official Title
    Evaluation of The Results of Closed Kinetic Chain Exercises Applied in The Conservative Treatment of Patellofemoral Pain Syndrome by Means of Shear Wave Elastography: A Randomized Controlled Trial
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    June 2022
    Overall Recruitment Status
    Completed
    Study Start Date
    December 2016 (Actual)
    Primary Completion Date
    December 2016 (Actual)
    Study Completion Date
    February 2018 (Actual)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Sponsor
    Name of the Sponsor
    Taksim Egitim ve Arastirma Hastanesi

    4. Oversight

    Studies a U.S. FDA-regulated Drug Product
    No
    Studies a U.S. FDA-regulated Device Product
    No

    5. Study Description

    Brief Summary
    Non-selective closed kinetic chain exercises and or selective closed kinetic chain exercises has been shown to increase Vastus medialis obliquus muscle power in patellofemoral pain syndrome. However, the superiority of the exercises to each other has not been shown. This study aimed to evaluating the effects of different exercises on the stiffness of the Vastus medialis obliquus and vastus lateralis muscles, pain management, functional scores, and thigh circumferences.
    Detailed Description
    This randomized-controlled clinical trial included 40 patients (20 male and 20 female) who were admitted to hospital and who were clinically diagnosed with single-sided patellofemoral pain syndrome (PFPS) and 40 healthy controls (20 male and 20 female). Each group were randomized into subgroups according to diseased side of the PFPS group (40 knees), healthy side of the PFPS group (40 knees) and both side of the healthy control group (80 knees). Randomization was applied with random-number generator (Research Randomizer. Version 4.0). Only one of the authors was aware of randomization. Examiner and patient were blind to the relevant group. Non-selective closed kinetic chain and selective closed kinetic chain exercises were applied for 6 weeks in all groups. Thigh circumference measurement was performed 5-10 cm above the upper pole of the patella. In addition, evaluation was made with visual analog score (VAS) and Lysholm Knee Score (LKS) score. Vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of the participants were measured with Shear Wave Elastography 1 day before the therapy and 6 weeks after therapy. Written informed consent was taken from each patient.This study is in line with the Declaration of Helsinki. Approval was obtained by the Local Ethics Committee (17/07/2016-258642).

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Exercise Training
    Keywords
    Elastography, exercises, non-selective, pain, patellofemoral

    7. Study Design

    Primary Purpose
    Treatment
    Study Phase
    Not Applicable
    Interventional Study Model
    Factorial Assignment
    Masking
    Participant
    Allocation
    Randomized
    Enrollment
    80 (Actual)

    8. Arms, Groups, and Interventions

    Arm Title
    Diseased side of the patellofemoral pain syndrome (PFPS) group (40 knees)
    Arm Type
    Experimental
    Arm Description
    Non-selective close kinetic chain exercises and selective close kinetic chain exercises were applied for 6 weeks in diseased side of the PFPS group. Thigh circumference measurement was performed 5-10 cm above the upper pole of the patella. In addition, evaluation was made with visual analog score (VAS) and Lysholm Knee score (LKS). Vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of the participants were measured with Shear Wave Elastography 1 day before the therapy and 6 weeks after therapy in hospital.
    Arm Title
    Healthy side of the patellofemoral pain syndrome (PFPS) group (40 knees)
    Arm Type
    Experimental
    Arm Description
    Non-selective close kinetic chain exercises and selective close kinetic chain exercises were applied for 6 weeks in healthy side of the PFPS group. Thigh circumference measurement was performed 5-10 cm above the upper pole of the patella. In addition, evaluation was made with visual analog score (VAS) and Lysholm Knee score (LKS). Vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of the participants were measured with Shear Wave Elastography 1 day before the therapy and 6 weeks after therapy in hospital.
    Arm Title
    Both side of the healthy control group (80 knees)
    Arm Type
    Other
    Arm Description
    Non-selective close kinetic chain exercises and selective close kinetic chain exercises were applied for 6 weeks in side of the both side of the healthy control group. Thigh circumference measurement was performed 5-10 cm above the upper pole of the patella. In addition, evaluation was made with visual analog score (VAS) and Lysholm Knee score (LKS). Vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of the participants were measured with Shear Wave Elastography 1 day before the therapy and 6 weeks after therapy in hospital.
    Intervention Type
    Other
    Intervention Name(s)
    Non-selective closed kinetic chain exercises (NSKCE) and selective closed kinetic chain exercises (SCKCE)
    Intervention Description
    Non-selective closed kinetic chain double-leg semi-squat exercise In this exercise, the standing patient leans his or her back against the wall and slides down the wall until the knees are about 45 degrees flexed. Daily program was determined as 5 sessions and 10 repeats. The knee stayed at flexion position for 10 seconds in each repeat, which aimed the contraction of quadriceps muscle. There is a relaxation period for 5 seconds between each repeat. Selective closed kinetic chain double-leg semi-squat exercise with hip adduction In this exercise, the standing patient leans his or her back against the wall, forces the knees for adduction by squeezing the pillow placed between the knees and slides down the wall until the knees are about 45 degrees flexed. Daily program was determined as 5 sessions and 10 repeats.
    Primary Outcome Measure Information:
    Title
    Shear Wave Elastography
    Description
    Measurement of muscle strength before exercises
    Time Frame
    1 day before exercise program
    Title
    Shear Wave Elastography
    Description
    Measurement of muscle strength after exercises
    Time Frame
    6 weeks after exercise program

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    17 Years
    Maximum Age & Unit of Time
    60 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: Having peripatellar/retropatellar pain while sitting,going up and down the stairs Walking for a long time, crouching down, running, and kneeling down Having a VAS score of ≥3 during the evaluation and not developing these symptoms on a traumatic basis Exclusion Criteria: Tendinitis Osgood-Schlatter Syndrome Traumatic hip or knee injuries Osteoarthritis Plica syndrome Sinding-Larsen-Johansson syndrome Ligamentous instability Spinal pain Chondral lesion Patellar tendon pathology Distraction apophysitis of knee circumference

    12. IPD Sharing Statement

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    Evaluation of the Results of Closed Kinetic Chain Exercises in Patellofemoral Pain Syndrome

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